Academic Journal
Evaluating the efficacy of rTMS for the management of pain and psychological aspects in non-central nervous system cancer patients: a systematic review.
| Τίτλος: | Evaluating the efficacy of rTMS for the management of pain and psychological aspects in non-central nervous system cancer patients: a systematic review. |
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| Συγγραφείς: | Luisi J; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy. Electronic address: jenny.luisi@ieo.it., Capetti B; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Conti L; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Grasso R; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Pravettoni G; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. |
| Πηγή: | Neurophysiologie clinique = Clinical neurophysiology [Neurophysiol Clin] 2025 Nov; Vol. 55 (6), pp. 103110. Date of Electronic Publication: 2025 Oct 03. |
| Τύπος έκδοσης: | Journal Article; Systematic Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: France NLM ID: 8804532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1769-7131 (Electronic) Linking ISSN: 09877053 NLM ISO Abbreviation: Neurophysiol Clin Subsets: MEDLINE |
| Imprint Name(s): | Publication: Paris : Elsevier Original Publication: Amsterdam ; New York : Elsevier, c1988- |
| Ιατρικοί όροι (MeSH): | Cancer Pain*/therapy , Cancer Pain*/psychology , Neoplasms*/complications , Neoplasms*/psychology , Pain Management*/methods , Transcranial Magnetic Stimulation*/methods, Humans ; Quality of Life |
| Περίληψη: | Objectives: Non-invasive brain stimulation techniques-particularly repetitive transcranial magnetic stimulation (rTMS) have emerged as promising alternatives to traditional pharmacological treatments for pain management in non-central nervous system cancer patients. By modulating neural circuits involved in pain processing through mechanisms of neuroplasticity, these interventions may also improve cognitive functioning, psychological aspects, and quality of life (QoL). The present systematic review aims to investigate the use of rTMS for cancer-related pain and psychological aspects. Methods: A comprehensive search was conducted in three electronic scientific databases-PubMed, Scopus, and Embase. Six studies were identified and included, comprising pilot studies, randomized controlled trials, and one randomized clinical trial. PRISMA 2020 guidelines for systematic review were followed. Results: All these studies investigated the use of rTMS to manage pain and psychological aspects such as QoL in patients with different types of oncological conditions, including breast, non-small cell lung, and gynecological cancer, multiple myeloma, and cell glioma. The results suggest a multidimensional improvement in QoL, well-being, and emotional dimension. Notably, a significant reduction in pain intensity was observed following rTMS treatment across all studies. Conclusion: Although limited in number, current studies suggest that rTMS is a promising non-pharmacological intervention for managing cancer-related pain and enhancing psychological well-being. Further high-quality trials are needed to confirm these findings and establish standardized treatment protocols. (Copyright © 2025. Published by Elsevier Masson SAS.) |
| Competing Interests: | Declaration of competing interest All the authors declare that they have no financial or personal relationships that could have influenced the work of this manuscript. |
| Contributed Indexing: | Keywords: Cancer-related pain; Non-invasive brain stimulation; Psychological aspects; Quality of life; Repetitive transcranial magnetic stimulation (rTMS) |
| Entry Date(s): | Date Created: 20251004 Date Completed: 20251121 Latest Revision: 20251124 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.neucli.2025.103110 |
| PMID: | 41045667 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1769-7131 |
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| DOI: | 10.1016/j.neucli.2025.103110 |