Academic Journal
Three-Dimensional Analysis of Bone Morphology of the Rheumatoid Arthritis Elbow.
| Τίτλος: | Three-Dimensional Analysis of Bone Morphology of the Rheumatoid Arthritis Elbow. |
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| Συγγραφείς: | Ikeda S; From the Department of Orthopaedic Surgery, Sakai City Medical Center, Osaka, Japan (Dr. Ikeda); the Department of Orthopaedic Surgery, The University of Osaka, Graduate School of Medicine, Osaka, Japan (Dr. Miyamura, Dr. Shiode, Dr. Murase, Dr. Oka); the Department of Orthopaedic Surgery, Daini Osaka Police Hospital, Osaka, Japan (Dr. Oura); the Department of Orthopaedic Surgery, Japan Community Health care Organization Osaka Hospital, Osaka, Japan (Dr. Miyoshi, Dr. Temporin., Dr. Shimada); the Department of Orthopaedic Surgery, National Hospital Organization Osaka Minami Medical Center, Osaka, Japan (Dr. Akita); the Department of Orthopaedic Surgery, Bellland General Hospital, Osaka, Japan (Dr. Murase); and the Department of Orthopaedic Biomaterial Science, The University of Osaka, Graduate School of Medicine, Osaka, Japan (Dr. Oka)., Miyamura S, Shiode R, Oura K, Miyoshi Y, Temporin K, Shimada K, Akita S, Murase T, Oka K |
| Πηγή: | Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews [J Am Acad Orthop Surg Glob Res Rev] 2025 Sep 22; Vol. 9 (9). Date of Electronic Publication: 2025 Sep 22 (Print Publication: 2025). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101724868 Publication Model: eCollection Cited Medium: Internet ISSN: 2474-7661 (Electronic) Linking ISSN: 24747661 NLM ISO Abbreviation: J Am Acad Orthop Surg Glob Res Rev Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Philadelphia, PA] : Wolters Kluwer Health, Inc., [2017]- |
| Ιατρικοί όροι (MeSH): | Arthritis, Rheumatoid*/diagnostic imaging , Arthritis, Rheumatoid*/pathology , Arthritis, Rheumatoid*/physiopathology , Elbow Joint*/diagnostic imaging , Elbow Joint*/pathology , Elbow Joint*/physiopathology , Humerus*/diagnostic imaging , Humerus*/pathology , Radius*/diagnostic imaging , Radius*/pathology , Imaging, Three-Dimensional*, Ulna/diagnostic imaging ; Ulna/pathology ; Humans ; Middle Aged ; Male ; Female ; Aged ; Tomography, X-Ray Computed ; Adult ; Range of Motion, Articular |
| Περίληψη: | Introduction: Accurate treatment of elbow rheumatoid arthritis (RA) requires understanding the joint destruction pattern. However, comprehensive bone-deformation patterns remain unclear. Thus, we aimed to quantitatively evaluate three-dimensional (3D) deformity in RA elbows compared with normal elbows. Methods: The authors created 3D CT models of the distal humerus, proximal ulna, and radial head for 26 elbows with RA (Larsen classification IV) and 26 normal elbows. These models were superimposed onto one reference bone, selected from normal elbows. The intermodel distance was measured at categorized anatomical regions of the individual bones, and the measurements were compared between the RA and normal elbows. Correlation between clinical outcomes, including range of motion and 3D deformities, were also assessed in the RA group. Results: RA elbows exhibited notable bone destruction in both the anterior-inferior region of the distal humerus (7.9 to 9.9 mm vs. 9.5 to 12.6 mm) and the trochlear notch (16.7 to 20.1 mm vs. 11.3 to 15.4 mm) compared with normal elbows, with all differences being statistically significant (P < 0.05). The radial head in RA elbow was shortened (2.24 ± 1.97 mm vs. -0.18 ± 0.59 mm; P < 0.05), with osteophyte formation, particularly on the lateral side (P < 0.05). Humeroulnar joint deformity correlated with flexion-extension limitation (R = 0.42 to 0.74), and the radial head correlated with forearm supination limitation (R = 0.57 to 0.58). Conclusion: Bone destruction was shown in the anterior-inferior region of the distal humerus and trochlear notch, and the radial head was shortened with osteophyte formation, resulting in a proximal shift of the forearm bones and impaired motion. This provides valuable insights into RA elbow pathology and contributes to advancements in treatment. (Copyright © 2025 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons.) |
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| Grant Information: | 22H03199 Japan Society for the Promotion of Science; 24K19578 Japan Society for the Promotion of Science; 23K08612 Japan Society for the Promotion of Science |
| Entry Date(s): | Date Created: 20250922 Date Completed: 20250922 Latest Revision: 20250925 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12456477 |
| DOI: | 10.5435/JAAOSGlobal-D-24-00384 |
| PMID: | 40981535 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2474-7661 |
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| DOI: | 10.5435/JAAOSGlobal-D-24-00384 |