Academic Journal
Toscana virus encephalitis with reversible self-limiting vasculopathy.
| Τίτλος: | Toscana virus encephalitis with reversible self-limiting vasculopathy. |
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| Συγγραφείς: | Noushad MA; Department of Neurology, University Hospitals Plymouth NHS Trust, Plymouth, UK., Muzumdar K; Department of Neurology, University Hospitals Plymouth NHS Trust, Plymouth, UK karan.muzumdar@nhs.net., Gouda M; Department of Neurology, University Hospitals Plymouth NHS Trust, Plymouth, UK., Kamat M; Deparment of Acute Medicine, University Hospitals Plymouth NHS Trust, Plymouth, UK., Handley J; Department of Neurology, University Hospitals Plymouth NHS Trust, Plymouth, UK. |
| Πηγή: | Practical neurology [Pract Neurol] 2026 May 14; Vol. 26 (3), pp. 276-278. Date of Electronic Publication: 2026 May 14. |
| Τύπος έκδοσης: | Journal Article; Case Reports |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101130961 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-7766 (Electronic) Linking ISSN: 14747758 NLM ISO Abbreviation: Pract Neurol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Feb. 2006- : London : BMJ Pub. Group Original Publication: 2001-2005 : Oxford, UK : Blackwell Science |
| Ιατρικοί όροι (MeSH): | Encephalitis, Viral*/complications , Encephalitis, Viral*/diagnosis , Phlebotomus Fever*/complications , Bunyaviridae Infections*/complications , Sandfly fever Naples virus*, Humans ; Male ; Aged |
| Περίληψη: | Toscana virus (named after Tuscany, Italy) is an arthropod borne virus transmitted by sandflies. It is common in the Mediterranean region, several southern European countries and some North African countries, but is rare in the UK. Most Toscana virus infections are asymptomatic, but severe infections can have neurological manifestations. Toscana virus encephalitis is an uncommon self-limiting encephalitis with a vasculopathy. We report an elderly man who developed Toscana virus encephalitis and vasculopathy causing multiple ischaemic strokes with evidence of reversible intravascular stenosis, after a brief holiday on a Mediterranean cruise. The diagnosis is confirmed by detecting the presence of the virus in the cerebrospinal fluid (CSF) using real-time reverse transcriptase - PCR (RT-PCR) tests, and by a rise in antibody titres in serum. The treatment of Toscana virus infections is mainly symptomatic. Toscana virus infection should be considered in returning travellers who develop a febrile illness with confusion. (© Author(s) (or their employer(s)) 2026. No commercial re-use. See rights and permissions. Published by BMJ Group.) |
| Competing Interests: | Competing interests: None declared. |
| Contributed Indexing: | Keywords: CEREBROVASCULAR; CLINICAL NEUROLOGY; INFECTIOUS DISEASES; NEUROVIROLOGY |
| Entry Date(s): | Date Created: 20250814 Date Completed: 20260514 Latest Revision: 20260514 |
| Update Code: | 20260515 |
| DOI: | 10.1136/pn-2024-004419 |
| PMID: | 40813068 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1474-7766 |
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| DOI: | 10.1136/pn-2024-004419 |