Academic Journal
A rare case of primary invasive urothelial carcinoma of the renal pelvis and calyx: a case report.
| Τίτλος: | A rare case of primary invasive urothelial carcinoma of the renal pelvis and calyx: a case report. |
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| Συγγραφείς: | Oluwafemi OOA; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria.; https://orcid.org/0000-0002-4044-3418., Kasiemobi EU; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria., Babatunde M; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria., Adedeji BK; Histopathology Department, Federal University of Health Sciences, PMB 145, Otukpo, Benue State, 972101, Nigeria., Olaoluwa OO; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria., Azeez IA; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria., Obumneme EO; Department of Anatomic Pathology and Forensic Medicine, Afe Babalola University, PMB 5454, Ado-Ekiti, Ekiti State, 3601102, Nigeria. |
| Πηγή: | Ecancermedicalscience [Ecancermedicalscience] 2025 Jun 20; Vol. 19, pp. 1928. Date of Electronic Publication: 2025 Jun 20 (Print Publication: 2025). |
| Τύπος έκδοσης: | Case Reports; Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: ecancer Country of Publication: England NLM ID: 101392236 Publication Model: eCollection Cited Medium: Print ISSN: 1754-6605 (Print) Linking ISSN: 17546605 NLM ISO Abbreviation: Ecancermedicalscience Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Publication: Bristol, UK : ecancer Original Publication: Bristol, UK : Cancer Intelligence |
| Περίληψη: | Upper urinary tract urothelial carcinomas (UTUCs) are rare malignant neoplasms, representing about 5% of all urothelial carcinomas (UCs). The incidence of primary UTUC in the renal pelvis and calyx is quite rare. UTUC is a high-grade tumour with a poor prognosis at presentation. Characteristically, UTUC presents with symptoms such as gross and microscopic hematuria or flank pain. Its mode of definitive diagnosis remains histopathology examination, despite using computed tomography urography (CTU) as the gold imaging standard. However, atypical clinical presentations and abnormal radiologic findings could lead to misdiagnosis of UTUC. We report a 59-year-old male who presented with recurrent left flank pain of 2 years duration, and an episode of hematuria. A CTU showed no classic radiologic feature of upper UCs; however, his abdominal magnetic resonance imaging was suggestive. He subsequently had a left radical nephroureterectomy. The post-operative histology report showed a primary invasive high-grade UC of the left renal pelvis and calyx. He was counseled on the findings and placed on surveillance. There are few reported cases of UTUC of the renal pelvis and renal calyx; given that it is a rare malignancy. This is quite concerning, especially with the missed imaging finding by CTU. (© the authors; licensee ecancermedicalscience.) |
| Competing Interests: | The authors have no conflicts of interest to declare. |
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| Contributed Indexing: | Keywords: misdiagnosis; upper urinary tract; urothelial carcinoma |
| Entry Date(s): | Date Created: 20250703 Latest Revision: 20250704 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12221256 |
| DOI: | 10.3332/ecancer.2025.1928 |
| PMID: | 40606945 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1754-6605 |
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| DOI: | 10.3332/ecancer.2025.1928 |