Single Session of Calcium Hydroxylapatite, Incobotulinumtoxin A, and Hyaluronic Acid for Gluteal Aesthetic Improvement.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Single Session of Calcium Hydroxylapatite, Incobotulinumtoxin A, and Hyaluronic Acid for Gluteal Aesthetic Improvement.
Συγγραφείς: Di Sessa D; DSL Clinica, Private Practice, São Paulo, Brazil., Pecora CS; Clinica Dermatologie, Private Practice, São Paulo, Brazil., de Vasconcelos RCF; Department of Dermatology, Universidade de Santo Amaro, São Paulo, Brazil., Moreira GL; DSL Clinica Medica, Private Practice, São Paulo, Brazil.
Πηγή: Journal of cosmetic dermatology [J Cosmet Dermatol] 2025 May; Vol. 24 (5), pp. e70227.
Τύπος έκδοσης: Journal Article; Observational Study
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE
Imprint Name(s): Original Publication: Oxford, UK : Blackwell Science, c2002-
Ιατρικοί όροι (MeSH): Durapatite*/administration & dosage , Hyaluronic Acid*/administration & dosage , Botulinum Toxins, Type A*/administration & dosage , Dermal Fillers*/administration & dosage , Cellulite*/therapy , Cellulite*/diagnosis , Cosmetic Techniques*, Carboxymethylcellulose Sodium/administration & dosage ; Humans ; Female ; Middle Aged ; Retrospective Studies ; Adult ; Buttocks ; Treatment Outcome ; Esthetics ; Patient Satisfaction ; Skin Aging
Περίληψη: Background: While various techniques exist to treat the buttocks, few combine multiple products in a single session, offering both aesthetic and logistical benefits.
Aims: To evaluate the aesthetic improvement of the buttocks in patients treated with a combination of calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC), Incobotulinumtoxin A (IncoBoNT-A), and cohesive poly-densified matrix hyaluronic acid (CPM-HA V) in one session.
Patients/methods: This retrospective observational study involved women aged from 35 to 55 years who underwent the combined technique. Data were collected from the patient's charts, and photos were taken before treatment, and at 30 and 90 days post-procedure. Two independent physicians evaluated cellulite (5-point scale) and flaccidity (4-point scale) in all patients. Aesthetic improvements were assessed by patients and physicians using the GAIS (5-point) scale.
Results: Ten women aged 45.3 (±5.2) years participated. Initially, 80% presented moderate to severe flaccidity, and 30% and 90% presented moderate to very severe cellulite in relaxed and contracted buttocks, respectively. After 90 days, flaccidity improved in 9/10 patients, and cellulite in 4/10 and 9/10 patients in static and dynamic assessments, respectively. There was a moderate correlation between the assessments at baseline and after 90 days. The aesthetic appearance of the buttocks was rated as much improved or very much improved by 100% of the patients and 60% of the physicians after 90 days.
Conclusion: A single-session combined application of CaHA-CMC, IncoBoNT-A, and CPM-HA effectively improved flaccidity and cellulite, resulting in high patient satisfaction.
(© 2025 The Author(s). Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.)
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Grant Information: Merz Pharmaceuticals
Contributed Indexing: Keywords: aging; buttocks; calcium hydroxylapatite; hyaluronic acid; incobotulinum toxin A; sagging
Substance Nomenclature: 91D9GV0Z28 (Durapatite)
9004-61-9 (Hyaluronic Acid)
EC 3.4.24.69 (Botulinum Toxins, Type A)
EC 3.4.24.69 (incobotulinumtoxinA)
0 (Dermal Fillers)
K679OBS311 (Carboxymethylcellulose Sodium)
Entry Date(s): Date Created: 20250512 Date Completed: 20250512 Latest Revision: 20250528
Update Code: 20260130
PubMed Central ID: PMC12067859
DOI: 10.1111/jocd.70227
PMID: 40353559
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1473-2165
DOI:10.1111/jocd.70227