Academic Journal
Dentin permeability and tubule occlusion of dentin treated with NaF and TiF4 varnishes compared to Elmex Opti-namel and Biomin F toothpastes under simulated pulp pressure.
| Τίτλος: | Dentin permeability and tubule occlusion of dentin treated with NaF and TiF |
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| Συγγραφείς: | Mosquim V; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil; Dental Physical Sciences Unit, Centre for Oral Bioengineering, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Gillam DG; Dental Physical Sciences Unit, Centre for Oral Bioengineering, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Magalhães AC; Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil., Wang L; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil. Electronic address: wang.linda@usp.br. |
| Πηγή: | Journal of dentistry [J Dent] 2025 Aug; Vol. 159, pp. 105812. Date of Electronic Publication: 2025 May 09. |
| Τύπος έκδοσης: | Journal Article; Comparative Study; Research Support, Non-U.S. Gov't |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE |
| Imprint Name(s): | Publication: Kidlington : Elsevier Original Publication: Bristol, Eng., Wright. |
| Ιατρικοί όροι (MeSH): | Dentin Permeability*/drug effects , Fluorides*/pharmacology , Sodium Fluoride*/pharmacology , Toothpastes*/pharmacology , Toothpastes*/chemistry , Dentin*/drug effects , Dentin*/ultrastructure , Fluorides, Topical*/pharmacology , Titanium*/pharmacology , Dental Pulp*/physiology , Dental Pulp*/drug effects, Chitosan/pharmacology ; Tooth Erosion/drug therapy ; Tooth Erosion/pathology ; Tin Fluorides/pharmacology ; Dentin Desensitizing Agents/pharmacology ; Silicates/pharmacology ; Humans ; Microscopy, Confocal ; Smear Layer ; Pressure ; Chemical Precipitation ; Citric Acid ; Tin Compounds |
| Περίληψη: | Objectives: To investigate if a NaF varnish, a TiF Methods: Permeability (n = 13/group) was measured under four conditions: with (LpMin) and without smear layer (LpMax), after treatment (LpTreat), and after erosion (LpEro, 1 min, 6 % citric acid). Specimens were analyzed using laser scanning confocal microscopy (LSCM), and the number of generated particles was quantified. Data were analyzed using mixed factorial ANOVA, 2-way ANOVA and Tukey's post-hoc tests (α=0.05). Results: Smear layer removal increased the permeability of all groups in nearly 80 %. Biomin F showed significantly lower LpTreat than TiF Conclusions: Only Biomin F reduced dentin permeability under simulated pulp pressure and maintained an effect after erosion. All products formed particles in the tubules and on the surface. Yet, erosion reduced the deposits for NaF varnish, but kept constant for TiF Clinical Significance: Despite its lower fluoride concentration, Biomin F toothpaste effectively reduced dentin permeability under simulated pulp pressure and after an erosive challenge in vitro, suggesting its potential for managing erosion-related dentin hypersensitivity. (Copyright © 2025 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Victor Mosquim reports financial support was provided by State of Sao Paulo Research Foundation. Linda Wang reports financial support was provided by State of Sao Paulo Research Foundation and National Council for Scientific and Technological Development. David Geoffrey Gillam has patent Bioactive glass composition licensed to Queen Mary and Westfield College, London (GB). Ana Carolina Magalhaes has patent Compósito dentário contendo tetrafluoreto de titânio na forma de verniz issued to University of São Paulo. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. DGG has patents on fluorine-containing bioactive glasses such as the one used in the Biomin F toothpaste used in this study. ACM has a patent on the TiF(4) varnish used in this study. |
| Contributed Indexing: | Keywords: Dentin sensitivity; Fluorapatite; Fluorides; Stannous chloride; Tin fluorides; Titanium tetrafluoride; Tooth erosion |
| Substance Nomenclature: | Q80VPU408O (Fluorides) 8ZYQ1474W7 (Sodium Fluoride) 0 (Toothpastes) 0 (Fluorides, Topical) T08RW8YRG1 (titanium tetrafluoride) D1JT611TNE (Titanium) 9012-76-4 (Chitosan) 0 (Tin Fluorides) 2968PHW8QP (Citric Acid) 0 (Dentin Desensitizing Agents) 1BQV3749L5 (stannous chloride) 0 (Silicates) 0 (Tin Compounds) |
| Entry Date(s): | Date Created: 20250511 Date Completed: 20250613 Latest Revision: 20260610 |
| Update Code: | 20260610 |
| DOI: | 10.1016/j.jdent.2025.105812 |
| PMID: | 40349908 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1879-176X |
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| DOI: | 10.1016/j.jdent.2025.105812 |