Academic Journal
Peritrophic matrix: an important determinant of vector competence in hematophagous arthropods.
| Τίτλος: | Peritrophic matrix: an important determinant of vector competence in hematophagous arthropods. |
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| Συγγραφείς: | Hodžić A; Centre for Microbiology and Environmental Systems Science (CMESS), Department of Microbiology and Ecosystem Science, Division of Microbial Ecology (DoME), University of Vienna, 1030 Vienna, Austria. Electronic address: adnan.hodzic@univie.ac.at., Duscher GG; AGES Research Services, Austrian Agency for Health and Food Safety, 2340 Mödling, Austria., Alić A; Department of Clinical Sciences of Veterinary Medicine, Faculty of Veterinary Medicine, University of Sarajevo, 71000 Sarajevo, Bosnia and Herzegovina., Beck R; Department for Bacteriology and Parasitology, Croatian Veterinary Institute, 10000 Zagreb, Croatia., Berry D; Centre for Microbiology and Environmental Systems Science (CMESS), Department of Microbiology and Ecosystem Science, Division of Microbial Ecology (DoME), University of Vienna, 1030 Vienna, Austria; Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna, 1030 Vienna, Austria. |
| Πηγή: | Trends in parasitology [Trends Parasitol] 2025 May; Vol. 41 (5), pp. 374-386. Date of Electronic Publication: 2025 Mar 27. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Science Country of Publication: England NLM ID: 100966034 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-5007 (Electronic) Linking ISSN: 14714922 NLM ISO Abbreviation: Trends Parasitol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Oxford, UK : Elsevier Science, c2001- |
| Ιατρικοί όροι (MeSH): | Arthropod Vectors*/immunology , Arthropod Vectors*/physiology , Arthropods*/immunology , Arthropods*/physiology , Arthropods*/parasitology, Animals ; Immunity, Innate |
| Περίληψη: | The peritrophic matrix (PM) is a non-cellular, glycan-rich structure that lines the gut epithelium of most invertebrates, including arthropod vectors that transmit diseases of public health and veterinary concern. This semipermeable barrier, functionally analogous to the vertebrate mucosal layer, separates the gut lumen from epithelial cells and provides protection against invading pathogens and their toxins. Beyond its mechanical protective role in the gut, the PM plays a crucial part in arthropod innate immunity. Here, we summarize the most recent advances in understanding the molecular mechanisms of vector-pathogen interactions in blood-feeding arthropods and discuss the significance of the PM in modulating vector competence. This knowledge could contribute to the development of novel strategies to control vector-borne infections. (Copyright © 2025 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
| Competing Interests: | Declaration of interests The authors declare that they have no conflicts of interest. |
| Contributed Indexing: | Keywords: blood-feeding arthropods; interactions; pathogen; peritrophic matrix; vector competence |
| Entry Date(s): | Date Created: 20250327 Date Completed: 20250509 Latest Revision: 20250509 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.pt.2025.03.005 |
| PMID: | 40148178 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1471-5007 |
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| DOI: | 10.1016/j.pt.2025.03.005 |