Academic Journal
Achieving Biomedically Desirable Nitric Oxide Release from Glucose Monitor Surfaces Via a Cu-Based Catalyst Coating.
| Title: | Achieving Biomedically Desirable Nitric Oxide Release from Glucose Monitor Surfaces Via a Cu-Based Catalyst Coating. |
|---|---|
| Authors: | Mohnike M; Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States., Melvin AC; Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States., Sharp JL; Sharp Analytics, LLC, Fort Collins, Colorado 80524, United States., Reynolds MM; Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States. |
| Source: | ACS applied bio materials [ACS Appl Bio Mater] 2024 Mar 18; Vol. 7 (3), pp. 1435-1440. Date of Electronic Publication: 2024 Mar 06. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: ACS Publications Country of Publication: United States NLM ID: 101729147 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-6422 (Electronic) Linking ISSN: 25766422 NLM ISO Abbreviation: ACS Appl Bio Mater Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Washington, DC : ACS Publications, [2018]- |
| MeSH Terms: | Nitric Oxide* , Metal-Organic Frameworks*, Reproducibility of Results ; Nitric Oxide Donors ; Glucose |
| Abstract: | We report the design of a blood-contacting glucose monitor with a nitric oxide (NO)-releasing metal-organic framework (MOF) embedded within the outer polymer layer of a glucose sensor to promote the release of NO from endogenous NO donors. The sensors were tested by using amperometry across a range of glucose concentrations to assess whether the presence of either the MOF or NO decreased the performance of the glucose monitor. Even though signal response was diminished, the sensors maintained a good regression fit (R2 = 0.9944) and a similar dynamic range and reproducibility in the presence of S-nitrosoglutathione. |
| Contributed Indexing: | Keywords: MOF-polymer composite; Metal−organic framework; S-nitrosogluathione; endogenous nitric oxide; glucose sensor |
| Substance Nomenclature: | 31C4KY9ESH (Nitric Oxide) 0 (Nitric Oxide Donors) 0 (Metal-Organic Frameworks) IY9XDZ35W2 (Glucose) |
| Entry Date(s): | Date Created: 20240306 Date Completed: 20240319 Latest Revision: 20240611 |
| Update Code: | 20260130 |
| DOI: | 10.1021/acsabm.4c00100 |
| PMID: | 38447089 |
| Database: | MEDLINE |
| ISSN: | 2576-6422 |
|---|---|
| DOI: | 10.1021/acsabm.4c00100 |