Academic Journal
DNA nanostructure decoration: a how-to tutorial.
| Τίτλος: | DNA nanostructure decoration: a how-to tutorial. |
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| Συγγραφείς: | Piantanida L; Faculty of Applied Science, School of Engineering, University of British Columbia, Kelowna, B.C., V1V 1V7, Canada., Liddle JA; National Institute of Standards and Technology, Gaithersburg, MD, 20878, United States of America., Hughes WL; Faculty of Applied Science, School of Engineering, University of British Columbia, Kelowna, B.C., V1V 1V7, Canada., Majikes JM; National Institute of Standards and Technology, Gaithersburg, MD, 20878, United States of America. |
| Πηγή: | Nanotechnology [Nanotechnology] 2024 Apr 23; Vol. 35 (27). Date of Electronic Publication: 2024 Apr 23. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: IOP Pub Country of Publication: England NLM ID: 101241272 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6528 (Electronic) Linking ISSN: 09574484 NLM ISO Abbreviation: Nanotechnology Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Bristol, UK : IOP Pub., c1990- |
| Ιατρικοί όροι (MeSH): | DNA*/chemistry , Nanostructures*/chemistry , Nanotechnology*/methods, Quantum Dots/chemistry ; Metal Nanoparticles/chemistry |
| Περίληψη: | DNA Nanotechnology is being applied to multiple research fields. The functionality of DNA nanostructures is significantly enhanced by decorating them with nanoscale moieties including: proteins, metallic nanoparticles, quantum dots, and chromophores. Decoration is a complex process and developing protocols for reliable attachment routinely requires extensive trial and error. Additionally, the granular nature of scientific communication makes it difficult to discern general principles in DNA nanostructure decoration. This tutorial is a guidebook designed to minimize experimental bottlenecks and avoid dead-ends for those wishing to decorate DNA nanostructures. We supplement the reference material on available technical tools and procedures with a conceptual framework required to make efficient and effective decisions in the lab. Together these resources should aid both the novice and the expert to develop and execute a rapid, reliable decoration protocols. (Creative Commons Attribution license.) |
| Contributed Indexing: | Keywords: DNA nanotechnology; DNA origami; tutorial |
| Substance Nomenclature: | 9007-49-2 (DNA) |
| Entry Date(s): | Date Created: 20240219 Date Completed: 20240423 Latest Revision: 20240509 |
| Update Code: | 20260130 |
| DOI: | 10.1088/1361-6528/ad2ac5 |
| PMID: | 38373400 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1361-6528 |
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| DOI: | 10.1088/1361-6528/ad2ac5 |