Academic Journal
Anti-diabetic and anti-urease potential of Osbeckia nutans Wall. leaves.
| Τίτλος: | Anti-diabetic and anti-urease potential of Osbeckia nutans Wall. leaves. |
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| Συγγραφείς: | Chelleng N; Natural Product Chemistry Section, CSIR-North East Institute of Science and Technology, Naharlagun, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Hazarika M; Natural Product Chemistry Section, CSIR-North East Institute of Science and Technology, Naharlagun, India., Sonia H; Natural Product Chemistry Section, CSIR-North East Institute of Science and Technology, Naharlagun, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Dihingia A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Biological Science & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, India., Manna P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Biological Science & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, India., Puzari M; Department of Life Sciences, Dibrugarh University, Dibrugarh, India., Chetia P; Department of Life Sciences, Dibrugarh University, Dibrugarh, India., Tamuly C; Natural Product Chemistry Section, CSIR-North East Institute of Science and Technology, Naharlagun, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India. |
| Πηγή: | Natural product research [Nat Prod Res] 2024 Nov; Vol. 38 (21), pp. 3870-3875. Date of Electronic Publication: 2023 Oct 06. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| Ιατρικοί όροι (MeSH): | Plant Leaves*/chemistry , Hypoglycemic Agents*/pharmacology , Hypoglycemic Agents*/chemistry , Urease*/metabolism , Plant Extracts*/pharmacology , Plant Extracts*/chemistry, alpha-Glucosidases/metabolism ; Flavonoids/pharmacology ; Flavonoids/chemistry ; Glycoside Hydrolase Inhibitors/pharmacology ; Glycoside Hydrolase Inhibitors/chemistry ; Quercetin/pharmacology ; Quercetin/chemistry ; Glucose Transporter Type 4/metabolism ; Helicobacter pylori/drug effects ; Asteraceae/chemistry ; Luteolin/pharmacology ; Luteolin/chemistry ; Glucose/metabolism ; Catechin/pharmacology ; Catechin/chemistry ; Animals |
| Περίληψη: | A study was conducted to investigate the anti-diabetic and anti-urease potential of Osbeckia nutans leaves (ONL). Six compounds, i.e. quercetin-3-O-glucoside, myricetin, shikimic acid, catechin, trans-ferulic acid and luteolin were identified from the butanol sub-fraction, BE2 and the ethyl acetate sub-fraction, EA5 of ONL. BE2 inhibited α-glucosidase and Jack bean urease with IC |
| Contributed Indexing: | Keywords: H. pylori urease; Osbeckia nutans; cellular glucose uptake; chemical constituents; molecular docking; α-glucosidase |
| Substance Nomenclature: | 0 (Hypoglycemic Agents) EC 3.5.1.5 (Urease) 0 (Plant Extracts) EC 3.2.1.20 (alpha-Glucosidases) 0 (Flavonoids) 0 (Glycoside Hydrolase Inhibitors) 9IKM0I5T1E (Quercetin) 76XC01FTOJ (myricetin) 0 (Glucose Transporter Type 4) KUX1ZNC9J2 (Luteolin) IY9XDZ35W2 (Glucose) 8R1V1STN48 (Catechin) |
| Entry Date(s): | Date Created: 20231006 Date Completed: 20241009 Latest Revision: 20241009 |
| Update Code: | 20260130 |
| DOI: | 10.1080/14786419.2023.2265039 |
| PMID: | 37799112 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1478-6427 |
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| DOI: | 10.1080/14786419.2023.2265039 |