Academic Journal

EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY - A COHORT STUDY OF 118 CASES.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY - A COHORT STUDY OF 118 CASES.
Συγγραφείς: Zaafouri H; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis., Cherif M; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis., Khedhiri N; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis., Mesbahi M; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis., Zebda H; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis., Jouini R; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, Cytopathology - Tunis., Bellali H; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, Epidemiology and Public Health - Tunis., Ben Maamer A; University Tunis El Manar, Faculty of Medicine of Tunis, Habib Thameur Hospital, General Surgery - Tunis.
Πηγή: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2023 Jan 09; Vol. 35, pp. e1706. Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2023).
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Colégio Brasileiro de Cirurgia Digestiva Country of Publication: Brazil NLM ID: 9100283 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6326 (Electronic) Linking ISSN: 01026720 NLM ISO Abbreviation: Arq Bras Cir Dig Subsets: MEDLINE
Imprint Name(s): Publication: São Paulo, Brasil : Colégio Brasileiro de Cirurgia Digestiva
Original Publication: São Paulo, Brasil : Disciplina de Cirurgia do Aparelho Digestivo do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Ιατρικοί όροι (MeSH): Colectomy*/adverse effects , Colonic Neoplasms*/complications , Colonic Neoplasms*/surgery , Colonic Neoplasms*/pathology, Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Humans ; Cohort Studies ; Retrospective Studies ; Risk Factors ; Morbidity
Περίληψη: Background: Occlusion is the most common complication of colon cancer. Surgical treatment is associated with the highest morbidity and mortality rate (10-27%) and has the worst prognosis. It is necessary for immediate management, avoiding colic perforation and peritonitis. The increase in mortality in emergency colon cancer surgery is multifactorial.
Aims: The aim of this study was to identify the risk factors for early postoperative mortality that highlights the therapeutic strategy in the management of obstructive colon cancer.
Methods: A retrospective study was performed on patients admitted from 2008 to 2020 at the Department of General Surgery due to obstructive colon cancer and operated on as an emergency (within 24 h of admission).
Results: In all, 118 patients with colon cancer were operated, and the early postoperative mortality was 10.2%. The univariate analysis highlighted that the American Society of Anesthesiology score III or IV, perforation tumor, one postoperative complication, and two simultaneous postoperative complications were considered significant risk factors for early postoperative mortality after emergent surgery. Multivariate analysis showed that only tumor perforation and the occurrence of two postoperative complications were significant risk factors.
Conclusion: This study showed that postoperative complication is the leading cause of early postoperative mortality after emergency surgery for obstructive colon cancer. Optimizing the postoperative management of these higher risk patients is still necessary and may reduce the mortality rate.
References: Br J Surg. 2019 Mar;106(4):477-483. (PMID: 30259967)
Br J Surg. 2005 Jan;92(1):94-100. (PMID: 15521083)
Colorectal Dis. 2009 Sep;11(7):733-9. (PMID: 18624817)
Ann Surg. 2004 Jul;240(1):76-81. (PMID: 15213621)
Arch Surg. 2005 Mar;140(3):278-83, discussion 284. (PMID: 15781793)
Br J Surg. 2008 Aug;95(8):1012-9. (PMID: 18563787)
Dis Colon Rectum. 2019 Aug;62(8):941-951. (PMID: 31283592)
Colorectal Dis. 2013 Sep;15(9):1100-6. (PMID: 23634749)
BMC Gastroenterol. 2014 Apr 15;14:76. (PMID: 24735084)
Entry Date(s): Date Created: 20230111 Date Completed: 20230113 Latest Revision: 20230120
Update Code: 20260130
PubMed Central ID: PMC9831636
DOI: 10.1590/0102-672020220002e1706
PMID: 36629687
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:2317-6326
DOI:10.1590/0102-672020220002e1706