Academic Journal
Impact of COVID-19 on fertility and assisted reproductive technology (ART): a systematic review.
| Τίτλος: | Impact of COVID-19 on fertility and assisted reproductive technology (ART): a systematic review. |
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| Συγγραφείς: | Săndulescu MS; Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; andreea_veliscu@yahoo.com., Văduva CC, Siminel MA, Dijmărescu AL, Vrabie SC, Camen IV, Tache DE, Neamţu SD, Nagy RD, Carp-Velişcu A, Manolea MM |
| Πηγή: | Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie [Rom J Morphol Embryol] 2022 Jul-Sep; Vol. 63 (3), pp. 503-510. |
| Τύπος έκδοσης: | Systematic Review; Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Editura Academiei Române Country of Publication: Romania NLM ID: 9112454 Publication Model: Print Cited Medium: Internet ISSN: 2066-8279 (Electronic) Linking ISSN: 12200522 NLM ISO Abbreviation: Rom J Morphol Embryol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Bucuresti, România : Editura Academiei Române, [1990- |
| Ιατρικοί όροι (MeSH): | COVID-19*/complications , Infertility*, Humans ; Male ; Female ; SARS-CoV-2 ; Pandemics ; COVID-19 Vaccines ; Peptidyl-Dipeptidase A ; Fertility |
| Περίληψη: | The appearance of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a major obstacle for the performing of current medical activities throughout the world. COVID-19 has affected humanity in many ways, thus causing a great medical, social, economic, and political instability. The aim of this study was to make an analysis of the scientific data obtained by so far to highlight the impact that COVID-19 has had on fertility and assisted reproductive technology (ART). Infection with SARS-CoV-2 alters the normal immune response by local and systemic damage to tissues and organs. After the virus enters the body, the first lesions are produced in the respiratory tract. Extrapulmonary lesions specific to COVID-19 include acute renal lesions/acute kidney damage, hepatocellular lesions, neurological diseases, myocardial dysfunction and arrhythmia, gastrointestinal diseases but also genital impairment. The possible impairment of the male reproductive system is because angiotensin-converting enzyme 2 (ACE2) receptors are in an increased number in the testes, seminiferous duct cells, spermatogonia, Leydig cells and Sertoli cells. Many published studies to date have pointed out that COVID-19 could also affect female fertility and disrupt the functions of the female reproductive system. The theory that this virus can also be transmitted sexually and can cause infertility or testicular damage is supported by the fact that the virus can be isolated in the semen of COVID-19 patients but only during the disease. Choosing the best method of treating infertility during the COVID-19 pandemic is multifactorial, but the risk of infection and compliance with specific ART hygiene protocols must always be considered. Currently, there is no scientific basis regarding the fact that the COVID-19 vaccination would influence fertility. |
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| Substance Nomenclature: | 0 (COVID-19 Vaccines) EC 3.4.15.1 (Peptidyl-Dipeptidase A) |
| Entry Date(s): | Date Created: 20230102 Date Completed: 20230103 Latest Revision: 20240912 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC9926143 |
| DOI: | 10.47162/RJME.63.3.04 |
| PMID: | 36588488 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2066-8279 |
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| DOI: | 10.47162/RJME.63.3.04 |