Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
Συγγραφείς:	Assele DD; Department of nursing, Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia., Lendado TA; Wolaita Zone Health Department, Wolaita Sodo, Ethiopia., Awato MA; Wolaita Zone Health Department, Wolaita Sodo, Ethiopia., Workie SB; Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Faltamo WF; Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Πηγή:	PloS one [PLoS One] 2021 Aug 19; Vol. 16 (8), pp. e0254245. Date of Electronic Publication: 2021 Aug 19 (Print Publication: 2021).
Τύπος έκδοσης:	Journal Article
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Imprint Name(s):	Original Publication: San Francisco, CA : Public Library of Science
Ιατρικοί όροι (MeSH):	Hospitalization* , Hospitals, University, Craniocerebral Trauma/mortality, Craniocerebral Trauma/therapy ; Ethiopia/epidemiology ; Adolescent ; Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors
Περίληψη:	Introduction: Head injury is the leading cause of morbidity and mortality throughout the world, especially in resource-limited countries including Ethiopia. However, little is known about the mortality rate and its predictors among these patients in Ethiopia. Thus, the study aims to assess the incidence rate of mortality and its predictors among patients with head injury admitted at Hawassa University Comprehensive Specialized Hospital. Methods: Institutional based retrospective follow-up study was conducted among 1220 randomly selected head injury patients admitted from July 2017 to July 2019. Bivariable and multivariable Cox regression models were fitted to identify the predictors of mortality. Proportionality assumption was tested by a global test based on the Schoenfeld residuals test. Results: The incidence of the mortality rate was 2.26 (95%CI: 1.9-2.6) per 100-person day observation. The independent predictors of time to death were age above 65 years (AHR:3.49, 95%CI:1.63, 7.48), severe TBI (AHR: 8.8, 95%CI:5.13, 15.0), moderate TBI (AHR:3, 95%CI:1.73,5.31), hypotension (AHR:1.72, 95%CI: 1.11,2.66), hypoxia (AHR:1.92, 95%CI: 1.33,2.76), hyperthermia (AHR:1.8, 95%CI: 1.23,2.63) and hypoglycemic (AHR:1.94, 95%CI: 1.34, 2.81) positively associated with mortality, while underwent neurosurgery was negatively associated with mortality (AHR: 0.25, 95% CI: 0.11,0.53). Conclusion: The incidence of mortality rate among head injury patients was high. Older age, moderate and severe TBI, hypotension and hypoxia at admission, neurosurgical procedure, and the episode of hyperthermia and hypoglycemia during hospitalization were the independent predictors of mortality among head injury patients. Therefore, intervention to reduce earlier deaths should focus on the prevention of secondary brain insults.
Competing Interests:	No authors have competing interests.
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Entry Date(s):	Date Created: 20210819 Date Completed: 20211123 Latest Revision: 20211123
Update Code:	20260130
PubMed Central ID:	PMC8376017
DOI:	10.1371/journal.pone.0254245
PMID:	34411116
Βάση Δεδομένων:	MEDLINE

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ISSN:	1932-6203
DOI:	10.1371/journal.pone.0254245