Day-to-Day Change in Pulsatility Index Describes Anterior Cerebral Circulation Disturbance and Functional Outcomes in Pediatric Traumatic Brain Injury.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Day-to-Day Change in Pulsatility Index Describes Anterior Cerebral Circulation Disturbance and Functional Outcomes in Pediatric Traumatic Brain Injury.
Συγγραφείς:	Jordan JD; Karin E. Reuter-Rice, PhD CPNP-AC FCCM FAAN, is Associate Professor, Department of Pediatrics, Schools of Nursing and Medicine, Duke University, Durham, NC., Reuter-Rice KE
Πηγή:	The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses [J Neurosci Nurs] 2020 Oct; Vol. 52 (5), pp. 224-229.
Τύπος έκδοσης:	Journal Article; Observational Study
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: American Association of Neuroscience Nurses Country of Publication: United States NLM ID: 8603596 Publication Model: Print Cited Medium: Internet ISSN: 1945-2810 (Electronic) Linking ISSN: 08880395 NLM ISO Abbreviation: J Neurosci Nurs Subsets: MEDLINE
Imprint Name(s):	Publication: Chicago, Ill. : American Association of Neuroscience Nurses Original Publication: [Park Ridge, IL] : The Association, [c1986-
Ιατρικοί όροι (MeSH):	Cerebrovascular Circulation* , Pediatrics* , Severity of Illness Index* , Ultrasonography, Doppler, Transcranial, Brain Injuries, Traumatic/complications , Glasgow Outcome Scale/*statistics & numerical data, Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Neuroscience Nursing ; Prospective Studies
Περίληψη:	Background: Traumatic brain injury (TBI) is a significant source of morbidity and mortality in children. Transcranial Doppler (TCD) ultrasound measures the cerebral arterial circulation allowing for the calculation of pulsatility indices (PIs) that provide an assessment of cerebral blood flow alterations. However, the use of PI in children with TBI is poorly understood and may be an important measure for the nursing care of children. Objectives: The purpose of this article is to define day-to-day PI change and to describe its relationship to injury characteristics and functional outcomes in children with TBI. Method: We performed a secondary analysis of a prospective observational parent study of 40 children aged 2 months to 15 years with mild or moderate-severe TBI who had serial TCDs. Sequential TCD PI measurements of day-to-day change revealed several consistencies among the TBI severity groups. Results: Day-to-day PI change was higher in children with a moderate-severe injury (40%) when compared with those with a mild injury (21%). Greater day-to-day PI change was seen in children whose Glasgow Outcome Scale-Extended Pediatrics scores worsened (25%) compared with those who had an improved (19%) or unchanged (23%) scores. Discussion: This study is the first to report day-to-day PI change in children with TBI and provides early insights into anterior cerebral artery circulation alterations of children with TBI. Although further research is needed, this study provides early evidence that TCD may be a valuable noninvasive neuromonitoring option in the management of children with TBI.
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Grant Information:	P30 NR014139 United States NR NINR NIH HHS
Entry Date(s):	Date Created: 20200902 Date Completed: 20210505 Latest Revision: 20211002
Update Code:	20260130
PubMed Central ID:	PMC7483877
DOI:	10.1097/JNN.0000000000000533
PMID:	32868697
Βάση Δεδομένων:	MEDLINE

Περιγραφή
ISSN:	1945-2810
DOI:	10.1097/JNN.0000000000000533