Academic Journal
Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies.
| Τίτλος: | Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies. |
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| Συγγραφείς: | Kochanek PM; Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA., Tasker RC; Department of Neurology and Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Bell MJ; Critical Care Medicine, Children's National Medical Center, Washington, DC., Adelson PD; Pediatric Neurosurgery, BARROW Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ., Carney N; Pacific Northwest Evidence-based Practice Center, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR., Vavilala MS; Harborview Injury Prevention and Research Center (HIPRC), University of Washington, Seattle, WA., Selden NR; Department of Neurological Surgery, Oregon Health & Science University, Portland, OR., Bratton SL; University of Utah, Salt Lake City, UT., Grant GA; Department of Neurosurgery, Stanford University, Stanford, CA., Kissoon N; Department of Pediatrics, British Columbia's Children's Hospital, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada., Reuter-Rice KE; School of Nursing/School of Medicine, Department of Pediatrics, Division of Pediatric Critical Care Medicine, Duke University, Durham, NC., Wainwright MS; Division of Pediatric Neurology, University of Washington, Seattle Children's Hospital, Seattle, WA. |
| Πηγή: | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies [Pediatr Crit Care Med] 2019 Mar; Vol. 20 (3), pp. 269-279. |
| Τύπος έκδοσης: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100954653 Publication Model: Print Cited Medium: Internet ISSN: 1529-7535 (Print) Linking ISSN: 15297535 NLM ISO Abbreviation: Pediatr Crit Care Med Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Baltimore, MD : Lippincott Williams & Wilkins, c2000- |
| Ιατρικοί όροι (MeSH): | Practice Guidelines as Topic*, Brain Injuries, Traumatic/*therapy , Clinical Protocols/*standards, Barbiturates/administration & dosage ; Brain/physiopathology ; Brain Injuries, Traumatic/complications ; Cerebrovascular Circulation/physiology ; Decompressive Craniectomy/methods ; Hypothermia, Induced/methods ; Intracranial Hypertension/etiology ; Intracranial Hypertension/therapy ; Respiration, Artificial/methods ; Adolescent ; Algorithms ; Child ; Child, Preschool ; Consensus ; Glasgow Coma Scale ; Humans ; Infant |
| Περίληψη: | Objectives: To produce a treatment algorithm for the ICU management of infants, children, and adolescents with severe traumatic brain injury. Data Sources: Studies included in the 2019 Guidelines for the Management of Pediatric Severe Traumatic Brain Injury (Glasgow Coma Scale score ≤ 8), consensus when evidence was insufficient to formulate a fully evidence-based approach, and selected protocols from included studies. Data Synthesis: Baseline care germane to all pediatric patients with severe traumatic brain injury along with two tiers of therapy were formulated. An approach to emergent management of the crisis scenario of cerebral herniation was also included. The first tier of therapy focuses on three therapeutic targets, namely preventing and/or treating intracranial hypertension, optimizing cerebral perfusion pressure, and optimizing partial pressure of brain tissue oxygen (when monitored). The second tier of therapy focuses on decompressive craniectomy surgery, barbiturate infusion, late application of hypothermia, induced hyperventilation, and hyperosmolar therapies. Conclusions: This article provides an algorithm of clinical practice for the bedside practitioner based on the available evidence, treatment protocols described in the articles included in the 2019 guidelines, and consensus that reflects a logical approach to mitigate intracranial hypertension, optimize cerebral perfusion, and improve outcomes in the setting of pediatric severe traumatic brain injury. |
| Substance Nomenclature: | 0 (Barbiturates) WQ92Y2793G (barbituric acid) |
| Entry Date(s): | Date Created: 20190305 Date Completed: 20200504 Latest Revision: 20220409 |
| Update Code: | 20260130 |
| DOI: | 10.1097/PCC.0000000000001737 |
| PMID: | 30830015 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1529-7535 |
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| DOI: | 10.1097/PCC.0000000000001737 |