Academic Journal
Are gastric hyperplastic polyps an additional manifestation in celiac disease?: Results from a retrospective study.
| Τίτλος: | Are gastric hyperplastic polyps an additional manifestation in celiac disease?: Results from a retrospective study. |
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| Συγγραφείς: | Dore MP; Dipartimento di Medicina Clinica e Sperimentale, Clinica Medica, Viale San Pietro, Sassari, University of Sassari, Italy Baylor College of Medicine, Michael E. DeBakey, Houston, TX Dipartimento di Medicina, Sezione di Gastroenterologia, Piazza Lucio Severi, San Sisto (Perugia), University of Perugia, Italy., Pes GM, Rocchi C, Loria MF, Soro S, Bassotti G |
| Πηγή: | Medicine [Medicine (Baltimore)] 2017 Feb; Vol. 96 (5), pp. e5923. |
| Τύπος έκδοσης: | Journal Article; Observational Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins |
| Ιατρικοί όροι (MeSH): | Adenomatous Polyps/*epidemiology , Adenomatous Polyps/*pathology , Celiac Disease/*epidemiology , Stomach Neoplasms/*epidemiology , Stomach Neoplasms/*pathology, Gastrointestinal Agents/administration & dosage ; Helicobacter Infections/epidemiology ; Italy/epidemiology ; Adult ; Age Factors ; Aged ; Body Mass Index ; Endoscopy, Digestive System ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sex Factors |
| Περίληψη: | Gastric polyps are frequently reported in patients undergoing upper endoscopic procedures. In this retrospective study, the association between hyperplastic polyps and celiac disease in Northern Sardinia was estimated.Age, gender, body mass index, and medications taken in the 2 preceding months, including proton-pump inhibitors (PPIs), H2 receptor blockers (anti-H2), Helicobacter pylori status, endoscopic findings, and histology from charts of patients undergoing esophago-gastro-duodenoscopy were reviewed. Polyps were classified as hyperplastic, fundic gland, inflammatory, and adenomatous.3.7% (423/11379) patients had celiac disease. Prevalence of gastric polyps was 4.2% (3.8% among celiac vs 4.2% nonceliac patients). Inflammatory polyp was the most common histotype (55.8% and 56.2%) followed by fundic gland polyps (31.4% and 43.7%), hyperplastic (8.7% and 0%), and adenomas, in celiac and nonceliac patients, respectively. Fundic gland polyps were more common in PPI users (odds ratio: 4.06) than in nonusers (2.65, P = 0.001) among celiac and nonceliac patients. Age older than 50, female gender, esophago-gastro-duodenoscopy year, and PPI use were associated with the presence of polyps, whereas active H pylori infection was not.Gastric polyps were common in Sardinian patients undergoing esophago-gastro-duodenoscopy. However, the previously reported association between hyperplastic polyps and celiac disease was not confirmed in our study. |
| Competing Interests: | The authors have no funding and conflicts of interest to disclose. |
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| Substance Nomenclature: | 0 (Gastrointestinal Agents) |
| SCR Disease Name: | Polyposis, Gastric |
| Entry Date(s): | Date Created: 20170203 Date Completed: 20170227 Latest Revision: 20260127 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC5293433 |
| DOI: | 10.1097/MD.0000000000005923 |
| PMID: | 28151870 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1536-5964 |
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| DOI: | 10.1097/MD.0000000000005923 |