Academic Journal
Microcomputer programs for prediction and comparative evaluation of protein secondary structure from nucleotide sequence data: application to ribulose-1,5-bisphosphate carboxylase sequences.
| Τίτλος: | Microcomputer programs for prediction and comparative evaluation of protein secondary structure from nucleotide sequence data: application to ribulose-1,5-bisphosphate carboxylase sequences. |
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| Συγγραφείς: | Pongor S, Guttieri MJ, Cohen LM, Szalay AA |
| Πηγή: | DNA (Mary Ann Liebert, Inc.) [DNA] 1985 Aug; Vol. 4 (4), pp. 319-26. |
| Τύπος έκδοσης: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8302432 Publication Model: Print Cited Medium: Print ISSN: 0198-0238 (Print) Linking ISSN: 01980238 NLM ISO Abbreviation: DNA Subsets: MEDLINE |
| Imprint Name(s): | Publication: New York Ny : Mary Ann Liebert Original Publication: New York : M.A. Liebert, [c1981]-c1989. |
| Ιατρικοί όροι (MeSH): | Computers* , Ribulose-Bisphosphate Carboxylase*, Base Sequence ; Epitopes ; Genes ; Hydrogen Bonding ; Protein Conformation ; Solubility |
| Περίληψη: | Apple II PASCAL computer programs are described for routine evaluation of protein secondary structures predicted from DNA or amino acid sequence data. The programs predict protein secondary structure using the directional information algorithm of Garnier et al. (1978), and calculate hydrophobicity (Kyte and Doolittle, 1982), hydrophilicity (Hopp and Woods, 1981), hydrophobic moment (Eisenberg et al., 1984b), and secondary structure propensity profiles. The novel feature of these programs is the application of numeric and graphic methods, designed to facilitate detection and characterization of structural similarities/divergences using the aforementioned structural parameters. The use of the programs is demonstrated on a set of sequences from the large and small subunits of ribulose-1,5-bisphosphate carboxylase. |
| Substance Nomenclature: | 0 (Epitopes) EC 4.1.1.39 (Ribulose-Bisphosphate Carboxylase) |
| Entry Date(s): | Date Created: 19850801 Date Completed: 19851121 Latest Revision: 20061115 |
| Update Code: | 20260130 |
| DOI: | 10.1089/dna.1985.4.319 |
| PMID: | 2412771 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 0198-0238 |
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| DOI: | 10.1089/dna.1985.4.319 |