Academic Journal

[The effect of cerebrolysin on cognitive functions in childhood autism and in Asperger syndrome].

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: [The effect of cerebrolysin on cognitive functions in childhood autism and in Asperger syndrome].
Μεταγλωττισμένος Τίτλος: Vliianie tserebrolizina na kognitivnye funktsii pri detskom autizme i sindrome Aspergera.
Συγγραφείς: Krasnoperova MG, Bashina VM, Skvortsov IA, Simashkova NV
Πηγή: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2003; Vol. 103 (6), pp. 15-8.
Τύπος έκδοσης: Journal Article
Γλώσσα: Russian
Στοιχεία περιοδικού: Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 9712194 Publication Model: Print Cited Medium: Print ISSN: 1997-7298 (Print) Linking ISSN: 19977298 NLM ISO Abbreviation: Zh Nevrol Psikhiatr Im S S Korsakova Subsets: MEDLINE
Imprint Name(s): Publication: <1995->: Moskva : Media Sfera
Original Publication: Moskva : "Meditsina"
Ιατρικοί όροι (MeSH): Amino Acids/*therapeutic use , Asperger Syndrome/*drug therapy , Autistic Disorder/*drug therapy , Cognition/*drug effects , Nootropic Agents/*therapeutic use, Asperger Syndrome/physiopathology ; Autistic Disorder/physiopathology ; Cognition/physiology ; Child ; Child, Preschool ; Female ; Humans ; Male ; Treatment Outcome
Περίληψη: Nineteen children with childhood autism and 8 with Asperger's syndrome aged 2-8 year, were treated with cerebrolysin (CL) in inpatient clinic. All the patients received 10 microinjections (intramuscularly and perinervously) of 0.1 ml CL daily during 5 days. Clinical study was combined with device estimation of cognitive functions and communicative skills. CL therapy resulted in improvement of cognitive functions (expressive and receptive speech, fine motoring, playing). Positive effects were revealed in all the patients with Asperger's syndrome and in 89% of the patients with childhood autism. Any negative effects were not found. With regard to cognitive functions development, therapeutic efficacy proved to be more pronounced in the patients with Asperger's syndrome as compared to childhood autistic group (p < 0.005).
Substance Nomenclature: 0 (Amino Acids)
0 (Nootropic Agents)
37KZM6S21G (cerebrolysin)
Entry Date(s): Date Created: 20030723 Date Completed: 20031015 Latest Revision: 20161124
Update Code: 20260130
PMID: 12872620
Βάση Δεδομένων: MEDLINE