Bibliographic Details
| Title: |
A Novel Surface Texturing Technique for Biocompatible Materials and Its Influence on Cell Culture Behavior. |
| Authors: |
Kumar, Santosh1 (AUTHOR) santosh90 m@gmail.com, Jayswal, Suresh Chand1 (AUTHOR) |
| Source: |
Journal of Advanced Manufacturing Systems. May2026, p1-24. 24p. |
| Subject Terms: |
Biomedical materials, Titanium-aluminum-vanadium alloys, Electric metal-cutting, Microstructure, Antibacterial agents, Cell culture, Response surfaces (Statistics), Surface texture |
| Abstract: |
In this study, the surface morphology and array formation and their biocompatibility of Ti-6Al–4V alloy were analyzed. Several surface texturing techniques have been developed to modify surface characteristics with the aim of minimizing bacterial adhesion and colonization. The Wire Electrical Discharge Machining (WEDM) process was employed to fabricate square array micro pillar and cylindrical surfaces on Ti–6Al–4V alloy, given its extensive use in biomedical applications. Pillars and a cylindrical array help to regulate the surface cell interaction. The study aimed to optimize machining parameters of Ti–6Al–4V alloy by minimizing kerf width and overcut to enhance surface quality. Response Surface Methodology (RSM) with a Box–Behnken design was employed for experiments and process optimization. The optimized machining parameters obtained through multi-objective optimization were TON 13.51 μs, wire feed 6 m/min, and wire tension 7.35 gf, resulting in a minimum kerf width of 319.60 μm and overcut of 34.80 μm, with experimental values of 310.35 and 33.54 μm, showing less than 5% deviation. The fabricated microstructures exhibited well-defined geometries, with square micropillars ranging from 145 μm to 170 μm and cylindrical features of approximately 231 ± 10μm. Surface morphology analysis revealed the presence of recast layers, debris, micro-cracks, and edge rounding due to re-solidified material, while XRD results confirmed the retention of crystalline phases along with the formation of TiO2 on the machined surfaces. Antibacterial evaluation showed a significant reduction in bacterial adhesion, where untreated surfaces exhibited 1100 CFU, WEDM-treated planar surfaces showed 680 CFU, and square micro-array surfaces demonstrated only 97 CFU, corresponding to an approximate 88% reduction, while cylindrical structures showed about 61% reduction in bacterial growth. [ABSTRACT FROM AUTHOR] |
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| Database: |
Business Source Index |