Bibliographic Details
| Title: |
Universal Dental Adhesives Containing Zinc Oxide and Copper Nanoparticles Improve Interface on Caries‐Affected Dentin After 2 Years: In Vitro Study. |
| Authors: |
Gutiérrez, Mario Felipe1,2 (AUTHOR) mfgutierrez@uandes.cl, Aliaga‐Gálvez, Romina1 (AUTHOR), Ñaupari‐Villasante, Romina3 (AUTHOR), Fernández, Eduardo2,4 (AUTHOR), Loguercio, Alessandro D.3 (AUTHOR) aloguercio@hotmail.com |
| Source: |
Journal of Esthetic & Restorative Dentistry. May2026, Vol. 38 Issue 5, p970-980. 11p. |
| Subject Terms: |
*Copper analysis, *Metal analysis, *Dental bonding, *Materials testing, *In vitro studies, *Dental radiography, *Zinc oxide, *Research funding, *T-test (Statistics), *Data analysis, *Dentin, *Synthetic gums & resins, *Two-way analysis of variance, *Dental materials, *Dental cements, *Descriptive statistics, *Longitudinal method, *Experimental design, *Tensile strength, *X-rays, *Statistics, *Dental caries, *Comparative studies, *Data analysis software, *Nanoparticles, *Microbiological techniques |
| Abstract: |
Objective: To evaluate the effect of adding zinc oxide and copper nanoparticles (ZnO/CuNp) into universal adhesives (UAs) on resin–dentin microtensile bond strength (μTBS), nanoleakage (NL), and presence of ZnO/Cu within the hybrid layer on caries‐affected dentin, both at baseline (T0) and after 2 years of water storage (T2). Materials and Methods: ZnO/CuNp (0% [control]; 5/0.1 and 5/0.2 wt%) were added into Prime&Bond Active (PBA) and Ambar Universal (AMB). Ninety‐six extracted human third molars were used. After microbiological induction of caries‐affected dentin, UAs were applied in both etch‐and‐rinse and self‐etch modes, followed by composite build‐up. Specimens were sectioned to obtain resin–caries‐affected dentin bonded sticks for μTBS, NL, and chemical characterization of the hybrid layer for Cu and Zn detection at T0 and T2. Data were statistically analyzed (α = 0.05). Results: ZnO/CuNp had no effect on μTBS at T0 (p > 0.05) but improved μTBS at T2, compared to control (p < 0.05). Both UAs showed a significant decrease in μTBS over time (p < 0.05), except PBA with ZnO/CuNp in etch‐and‐rinse mode. NL was significantly lower in ZnO/CuNp‐containing UAs at both time points (p < 0.05), though all groups showed increased NL over time. ZnO/CuNp remained detectable in the hybrid layer at T2. Conclusions: Adding ZnO/CuNp to UAs decreased adhesive interface degradation on caries‐affected dentin, likely due to their presence within the hybrid layer even after 2 years. Clinical Significance: ZnO/Cu nanoparticles into UAs could enhance the stability of adhesive restorations on caries‐affected dentin by reducing interface degradation. [ABSTRACT FROM AUTHOR] |
| Database: |
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