eBook
Gene Expression Data Analysis : A Statistical and Machine Learning Perspective
| Τίτλος: | Gene Expression Data Analysis : A Statistical and Machine Learning Perspective |
|---|---|
| Περιγραφή: | Development of high-throughput technologies in molecular biology during the last two decades has contributed to the production of tremendous amounts of data. Microarray and RNA sequencing are two such widely used high-throughput technologies for simultaneously monitoring the expression patterns of thousands of genes. Data produced from such experiments are voluminous (both in dimensionality and numbers of instances) and evolving in nature. Analysis of huge amounts of data toward the identification of interesting patterns that are relevant for a given biological question requires high-performance computational infrastructure as well as efficient machine learning algorithms. Cross-communication of ideas between biologists and computer scientists remains a big challenge.Gene Expression Data Analysis: A Statistical and Machine Learning Perspective has been written with a multidisciplinary audience in mind. The book discusses gene expression data analysis from molecular biology, machine learning, and statistical perspectives. Readers will be able to acquire both theoretical and practical knowledge of methods for identifying novel patterns of high biological significance. To measure the effectiveness of such algorithms, we discuss statistical and biological performance metrics that can be used in real life or in a simulated environment. This book discusses a large number of benchmark algorithms, tools, systems, and repositories that are commonly used in analyzing gene expression data and validating results. This book will benefit students, researchers, and practitioners in biology, medicine, and computer science by enabling them to acquire in-depth knowledge in statistical and machine-learning-based methods for analyzing gene expression data.Key Features: An introduction to the Central Dogma of molecular biology and information flow in biological systems A systematic overview of the methods for generating gene expression data Background knowledge on statistical modeling and machine learning techniques Detailed methodology of analyzing gene expression data with an example case study Clustering methods for finding co-expression patterns from microarray, bulkRNA, and scRNA data A large number of practical tools, systems, and repositories that are useful for computational biologists to create, analyze, and validate biologically relevant gene expression patterns Suitable for multidisciplinary researchers and practitioners in computer science and biological sciences |
| Συγγραφείς: | Pankaj Barah, Dhruba Kumar Bhattacharyya, Jugal Kumar Kalita |
| Resource Type: | eBook. |
| Θέματα: | Machine learning, Gene expression--Data processing, Gene expression--Statistical methods |
| Categories: | SCIENCE / Bioinformatics, SCIENCE / Life Sciences / Molecular Biology, COMPUTERS / Data Science / Machine Learning |
| Βάση Δεδομένων: | eBook Index |
| FullText | Text: Availability: 0 |
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| Header | DbId: edsebk DbLabel: eBook Index An: 2759780 RelevancyScore: 956 AccessLevel: 6 PubType: eBook PubTypeId: ebook PreciseRelevancyScore: 955.975708007813 |
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| Items | – Name: Title Label: Title Group: Ti Data: Gene Expression Data Analysis : A Statistical and Machine Learning Perspective – Name: Abstract Label: Description Group: Ab Data: Development of high-throughput technologies in molecular biology during the last two decades has contributed to the production of tremendous amounts of data. Microarray and RNA sequencing are two such widely used high-throughput technologies for simultaneously monitoring the expression patterns of thousands of genes. Data produced from such experiments are voluminous (both in dimensionality and numbers of instances) and evolving in nature. Analysis of huge amounts of data toward the identification of interesting patterns that are relevant for a given biological question requires high-performance computational infrastructure as well as efficient machine learning algorithms. Cross-communication of ideas between biologists and computer scientists remains a big challenge.Gene Expression Data Analysis: A Statistical and Machine Learning Perspective has been written with a multidisciplinary audience in mind. The book discusses gene expression data analysis from molecular biology, machine learning, and statistical perspectives. Readers will be able to acquire both theoretical and practical knowledge of methods for identifying novel patterns of high biological significance. To measure the effectiveness of such algorithms, we discuss statistical and biological performance metrics that can be used in real life or in a simulated environment. This book discusses a large number of benchmark algorithms, tools, systems, and repositories that are commonly used in analyzing gene expression data and validating results. This book will benefit students, researchers, and practitioners in biology, medicine, and computer science by enabling them to acquire in-depth knowledge in statistical and machine-learning-based methods for analyzing gene expression data.Key Features: An introduction to the Central Dogma of molecular biology and information flow in biological systems A systematic overview of the methods for generating gene expression data Background knowledge on statistical modeling and machine learning techniques Detailed methodology of analyzing gene expression data with an example case study Clustering methods for finding co-expression patterns from microarray, bulkRNA, and scRNA data A large number of practical tools, systems, and repositories that are useful for computational biologists to create, analyze, and validate biologically relevant gene expression patterns Suitable for multidisciplinary researchers and practitioners in computer science and biological sciences – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pankaj+Barah%22">Pankaj Barah</searchLink><br /><searchLink fieldCode="AR" term="%22Dhruba+Kumar+Bhattacharyya%22">Dhruba Kumar Bhattacharyya</searchLink><br /><searchLink fieldCode="AR" term="%22Jugal+Kumar+Kalita%22">Jugal Kumar Kalita</searchLink> – Name: TypePub Label: Resource Type Group: TypPub Data: eBook. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Machine+learning%22">Machine learning</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression--Data+processing%22">Gene expression--Data processing</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression--Statistical+methods%22">Gene expression--Statistical methods</searchLink> – Name: SubjectBISAC Label: Categories Group: Su Data: <searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Bioinformatics%22">SCIENCE / Bioinformatics</searchLink><br /><searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Life+Sciences+%2F+Molecular+Biology%22">SCIENCE / Life Sciences / Molecular Biology</searchLink><br /><searchLink fieldCode="ZK" term="%22COMPUTERS+%2F+Data+Science+%2F+Machine+Learning%22">COMPUTERS / Data Science / Machine Learning</searchLink> |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsebk&AN=2759780 |
| RecordInfo | BibRecord: BibEntity: Classifications: – Code: 572.865 Scheme: ddc Type: prePub Languages: – Code: eng Text: English Subjects: – SubjectFull: Machine learning Type: general – SubjectFull: Gene expression--Data processing Type: general – SubjectFull: Gene expression--Statistical methods Type: general Titles: – TitleFull: Gene Expression Data Analysis : A Statistical and Machine Learning Perspective Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pankaj Barah – PersonEntity: Name: NameFull: Dhruba Kumar Bhattacharyya – PersonEntity: Name: NameFull: Jugal Kumar Kalita – PersonEntity: Name: NameFull: Pankaj Barah – PersonEntity: Name: NameFull: Dhruba Kumar Bhattacharyya – PersonEntity: Name: NameFull: Jugal Kumar Kalita IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2021 – D: 16 M: 11 Type: profile Y: 2021 Identifiers: – Type: isbn-print Value: 9780367338893 – Type: isbn-print Value: 9781032055756 – Type: isbn-print Value: 9781041204237 – Type: isbn-electronic Value: 9780429322655 – Type: isbn-electronic Value: 9781000425734 – Type: isbn-electronic Value: 9781000425758 Titles: – TitleFull: Gene Expression Data Analysis : A Statistical and Machine Learning Perspective Type: main |
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