Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R

Bibliographic Details
Title: Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R
Description: Analyzing high-dimensional gene expression and DNA methylation data with R is the first practical book that shows a ``pipeline'of analytical methods with concrete examples starting from raw gene expression and DNA methylation data at the genome scale. Methods on quality control, data pre-processing, data mining, and further assessments are presented in the book, and R programs based on simulated data and real data are included. Codes with example data are all reproducible. Features: • Provides a sequence of analytical tools for genome-scale gene expression data and DNA methylation data, starting from quality control and pre-processing of raw genome-scale data. • Organized by a parallel presentation with explanation on statistical methods and corresponding R packages/functions in quality control, pre-processing, and data analyses (e.g., clustering and networks). • Includes source codes with simulated and real data to reproduce the results. Readers are expected to gain the ability to independently analyze genome-scaled expression and methylation data and detect potential biomarkers. This book is ideal for students majoring in statistics, biostatistics, and bioinformatics and researchers with an interest in high dimensional genetic and epigenetic studies.
Authors: Hongmei Zhang
Resource Type: eBook.
Subjects: Gene expression--Data processing, Gene expression--Statistical methods, DNA--Methylation, R (Computer program language), Epigenetics--Statistical methods
Categories: SCIENCE / Bioinformatics, COMPUTERS / Data Science / Data Analytics
Database: eBook Index
FullText Text:
  Availability: 0
Header DbId: edsebk
DbLabel: eBook Index
An: 2481948
RelevancyScore: 950
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 949.708740234375
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Analyzing high-dimensional gene expression and DNA methylation data with R is the first practical book that shows a ``pipeline'of analytical methods with concrete examples starting from raw gene expression and DNA methylation data at the genome scale. Methods on quality control, data pre-processing, data mining, and further assessments are presented in the book, and R programs based on simulated data and real data are included. Codes with example data are all reproducible. Features: • Provides a sequence of analytical tools for genome-scale gene expression data and DNA methylation data, starting from quality control and pre-processing of raw genome-scale data. • Organized by a parallel presentation with explanation on statistical methods and corresponding R packages/functions in quality control, pre-processing, and data analyses (e.g., clustering and networks). • Includes source codes with simulated and real data to reproduce the results. Readers are expected to gain the ability to independently analyze genome-scaled expression and methylation data and detect potential biomarkers. This book is ideal for students majoring in statistics, biostatistics, and bioinformatics and researchers with an interest in high dimensional genetic and epigenetic studies.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Hongmei+Zhang%22">Hongmei Zhang</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Gene+expression--Data+processing%22">Gene expression--Data processing</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression--Statistical+methods%22">Gene expression--Statistical methods</searchLink><br /><searchLink fieldCode="DE" term="%22DNA--Methylation%22">DNA--Methylation</searchLink><br /><searchLink fieldCode="DE" term="%22R+%28Computer+program+language%29%22">R (Computer program language)</searchLink><br /><searchLink fieldCode="DE" term="%22Epigenetics--Statistical+methods%22">Epigenetics--Statistical methods</searchLink>
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PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsebk&AN=2481948
RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 572.865
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Gene expression--Data processing
        Type: general
      – SubjectFull: Gene expression--Statistical methods
        Type: general
      – SubjectFull: DNA--Methylation
        Type: general
      – SubjectFull: R (Computer program language)
        Type: general
      – SubjectFull: Epigenetics--Statistical methods
        Type: general
    Titles:
      – TitleFull: Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Hongmei Zhang
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            NameFull: Hongmei Zhang
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          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2020
            – D: 21
              M: 10
              Type: profile
              Y: 2020
          Identifiers:
            – Type: isbn-print
              Value: 9780367495169
            – Type: isbn-print
              Value: 9781498772594
            – Type: isbn-electronic
              Value: 9780429532368
            – Type: isbn-electronic
              Value: 9781498772600
            – Type: isbn-electronic
              Value: 9780429155192
          Titles:
            – TitleFull: Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R
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