Bibliographic Details
| Title: |
Membrane curvature governs the distribution of Piezo1 in live cells |
| Authors: |
Shilong Yang, Xinwen Miao, Steven Arnold, Boxuan Li, Alan T. Ly, Huan Wang, Matthew Wang, Xiangfu Guo, Medha M. Pathak, Wenting Zhao, Charles D. Cox, Zheng Shi |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| Description: |
This study demonstrates that the curvature of the cell membrane directly regulates the spatial distribution of Piezo1, a widely expressed mechanosensitive ion channel. Piezo1 may flatten upon activation and can mechanically inhibit membrane dynamics |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-35034-6 |
| Access URL: |
https://doaj.org/article/7c6e40022e03487d9d2a0edfa393acce |
| Accession Number: |
edsdoj.7c6e40022e03487d9d2a0edfa393acce |
| Database: |
Directory of Open Access Journals |