Academic Journal
NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL
| Τίτλος: | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
|---|---|
| Συγγραφείς: | A. S. Galjavich, S. N. Merjasev, R. A. Galjavi, R. F. Merjaseva |
| Πηγή: | Рациональная фармакотерапия в кардиологии, Vol 5, Iss 5, Pp 17-21 (2016) |
| Στοιχεία εκδότη: | Столичная издательская компания, 2016. |
| Έτος έκδοσης: | 2016 |
| Συλλογή: | LCC:Therapeutics. Pharmacology LCC:Diseases of the circulatory (Cardiovascular) system |
| Θεματικοί όροι: | N-терминальный про-мозговой натрийуретический пептид, хроническая сердечная недостаточность, выживаемость, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| Περιγραφή: | Aim. To study an importance of plasma N-terminal pro-brain natriuretic peptide (N-proBNP) in evaluation of severity and prognosis in patients with chronic heart failure (CHF) of ischemic genesis.Material and methods. 77 patients (60 men and 17 women; 59,4±10,7 y.o.) with CHF of ischemic genesis were included in the study. All patients had sinus rhythm and history of Q wave myocardial infarction. Standard examination was performed to all patients. Besides N-proBNP plasma level and patients yearly survival were evaluated.Results. N-proBNP plasma level had direct correlation with clinical indices (exercise tolerance, blood pressure, heart rate) and echocardiographic heart sizes. N-proBNP plasma level had relationship with prognosis of CHF patients. Baseline N-proBNP level was more than 2 times higher in died patients in comparison with survived patients. The yearly survival rate of CHF patients was 51,3% if N-proBNP level had been more than 400 fmol/ml (>15% of normal value). The clinico-laboratory index (based on N-proBNP plasma level) of severity and prognosis in CHF patients was developed.Conclusion. The clinico-laboratory index based on N-proBNP plasma level is easy to use and can improve medical practice. |
| Τύπος εγγράφου: | article |
| Περιγραφή αρχείου: | electronic resource |
| Γλώσσα: | English Russian |
| ISSN: | 1819-6446 2225-3653 |
| Relation: | http://www.rpcardio.ru/jour/article/view/707; https://doaj.org/toc/1819-6446; https://doaj.org/toc/2225-3653 |
| DOI: | 10.1234/1819-6446-2009-5-17-21 |
| Σύνδεσμος πρόσβασης: | https://doaj.org/article/1a1f4ab8cc3c4d58bf38fa4398fd3c72 |
| Αριθμός Καταχώρησης: | edsdoj.1a1f4ab8cc3c4d58bf38fa4398fd3c72 |
| Βάση Δεδομένων: | Directory of Open Access Journals |
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