Academic Journal
Associations of reallocating sedentary leisure-time to alternative discretionary movement behaviours with incident cardiometabolic diseases in 0.5 million Chinese adults
| Τίτλος: | Associations of reallocating sedentary leisure-time to alternative discretionary movement behaviours with incident cardiometabolic diseases in 0.5 million Chinese adults |
|---|---|
| Συγγραφείς: | Collings, PJ, Wang, M, Ho, HHS, Yeung, SLA, Siu, PM, Cowling, BJ, Sharp, SJ, Brage, S, Wareham, NJ, Du, H, Bennett, DA, Kim, Y |
| Συνεισφορές: | Group, China Kadoorie Biobank (CKB) Study Collaborative |
| Στοιχεία εκδότη: | Elsevier |
| Έτος έκδοσης: | 2025 |
| Συλλογή: | Oxford University Research Archive (ORA) |
| Περιγραφή: | Background In Chinese adults, there is a considerable burden of sedentary behaviour. This study aimed to estimate the implications of reallocating sedentary leisure-time to non-sedentary behaviours for incident cardiometabolic diseases. Methods A prospective cohort study of 462,370 Chinese adults (mean age 51 years; 59% female) who were free from diabetes and cardiovascular diseases at baseline. Isotemporal substitution Cox regression models were used to estimate the associations of reallocating self-reported sedentary leisure-time to the same amount of sleep, housework, Taichi, or conventional exercise (e.g., walking, jogging, ball games, swimming) with the risk of incident diabetes, stroke, and myocardial infarction (MI). The results are reported as adjusted hazard ratios and 95% confidence intervals per 30 min/day time exchanges. Potential impact fractions were calculated to estimate the proportional reductions in incident disease cases associated with time substitutions, assuming causality. Findings During >5.25 million person-years of follow-up, 19,738 incident diabetes, 51,460 stroke, and 6,767 MI cases were accrued. Lower disease risks were found for replacement of sedentary leisure-time by sleep (diabetes: 0.97 [0.95-0.99], stroke: 0.98 [0.97-0.99], MI: 0.97 [0.94-0.99]; in participants who slept <7 hours/day), housework (diabetes: 0.97 [0.97-0.98], stroke: 0.99 [0.98-0.99], MI: 0.97 [0.95-0.98]), Taichi (diabetes: 0.97 [0.95-0.99], stroke: 0.98 [0.97-0.99], MI: 0.95 [0.92-0.98]), or conventional exercise (diabetes: 0.97 [0.95-0.99], stroke: 0.97 [0.95-0.98], MI: 0.92 [0.88-0.96]). Potential impact fractions ranged from an estimated 3.5% (95% confidence interval: 3.1-3.9%) fewer cases of incident stroke when replacing sedentary leisure-time with housework, to an estimated 9.6% (5.9-13.3%) fewer cases of incident MI when reallocating sedentary leisure-time to conventional exercise. Interpretation Replacing sedentary leisure-time with behaviours such as housework, Taichi, sleep (in short sleepers) ... |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| Relation: | https://doi.org/10.1016/j.lanwpc.2025.101524 |
| DOI: | 10.1016/j.lanwpc.2025.101524 |
| Διαθεσιμότητα: | https://doi.org/10.1016/j.lanwpc.2025.101524 https://ora.ox.ac.uk/objects/uuid:64f20ec8-0aae-465a-b3ec-490196a85d7a |
| Rights: | info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) |
| Αριθμός Καταχώρησης: | edsbas.DE48A50B |
| Βάση Δεδομένων: | BASE |
| FullText | Text: Availability: 0 CustomLinks: – Url: https://doi.org/10.1016/j.lanwpc.2025.101524# Name: EDS - BASE (ns324271) Category: fullText Text: View record from BASE |
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| Items | – Name: Title Label: Title Group: Ti Data: Associations of reallocating sedentary leisure-time to alternative discretionary movement behaviours with incident cardiometabolic diseases in 0.5 million Chinese adults – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Collings%2C+PJ%22">Collings, PJ</searchLink><br /><searchLink fieldCode="AR" term="%22Wang%2C+M%22">Wang, M</searchLink><br /><searchLink fieldCode="AR" term="%22Ho%2C+HHS%22">Ho, HHS</searchLink><br /><searchLink fieldCode="AR" term="%22Yeung%2C+SLA%22">Yeung, SLA</searchLink><br /><searchLink fieldCode="AR" term="%22Siu%2C+PM%22">Siu, PM</searchLink><br /><searchLink fieldCode="AR" term="%22Cowling%2C+BJ%22">Cowling, BJ</searchLink><br /><searchLink fieldCode="AR" term="%22Sharp%2C+SJ%22">Sharp, SJ</searchLink><br /><searchLink fieldCode="AR" term="%22Brage%2C+S%22">Brage, S</searchLink><br /><searchLink fieldCode="AR" term="%22Wareham%2C+NJ%22">Wareham, NJ</searchLink><br /><searchLink fieldCode="AR" term="%22Du%2C+H%22">Du, H</searchLink><br /><searchLink fieldCode="AR" term="%22Bennett%2C+DA%22">Bennett, DA</searchLink><br /><searchLink fieldCode="AR" term="%22Kim%2C+Y%22">Kim, Y</searchLink> – Name: Author Label: Contributors Group: Au Data: Group, China Kadoorie Biobank (CKB) Study Collaborative – Name: Publisher Label: Publisher Information Group: PubInfo Data: Elsevier – Name: DatePubCY Label: Publication Year Group: Date Data: 2025 – Name: Subset Label: Collection Group: HoldingsInfo Data: Oxford University Research Archive (ORA) – Name: Abstract Label: Description Group: Ab Data: Background In Chinese adults, there is a considerable burden of sedentary behaviour. This study aimed to estimate the implications of reallocating sedentary leisure-time to non-sedentary behaviours for incident cardiometabolic diseases. Methods A prospective cohort study of 462,370 Chinese adults (mean age 51 years; 59% female) who were free from diabetes and cardiovascular diseases at baseline. Isotemporal substitution Cox regression models were used to estimate the associations of reallocating self-reported sedentary leisure-time to the same amount of sleep, housework, Taichi, or conventional exercise (e.g., walking, jogging, ball games, swimming) with the risk of incident diabetes, stroke, and myocardial infarction (MI). The results are reported as adjusted hazard ratios and 95% confidence intervals per 30 min/day time exchanges. Potential impact fractions were calculated to estimate the proportional reductions in incident disease cases associated with time substitutions, assuming causality. Findings During >5.25 million person-years of follow-up, 19,738 incident diabetes, 51,460 stroke, and 6,767 MI cases were accrued. Lower disease risks were found for replacement of sedentary leisure-time by sleep (diabetes: 0.97 [0.95-0.99], stroke: 0.98 [0.97-0.99], MI: 0.97 [0.94-0.99]; in participants who slept <7 hours/day), housework (diabetes: 0.97 [0.97-0.98], stroke: 0.99 [0.98-0.99], MI: 0.97 [0.95-0.98]), Taichi (diabetes: 0.97 [0.95-0.99], stroke: 0.98 [0.97-0.99], MI: 0.95 [0.92-0.98]), or conventional exercise (diabetes: 0.97 [0.95-0.99], stroke: 0.97 [0.95-0.98], MI: 0.92 [0.88-0.96]). Potential impact fractions ranged from an estimated 3.5% (95% confidence interval: 3.1-3.9%) fewer cases of incident stroke when replacing sedentary leisure-time with housework, to an estimated 9.6% (5.9-13.3%) fewer cases of incident MI when reallocating sedentary leisure-time to conventional exercise. Interpretation Replacing sedentary leisure-time with behaviours such as housework, Taichi, sleep (in short sleepers) ... – Name: TypeDocument Label: Document Type Group: TypDoc Data: article in journal/newspaper – Name: Language Label: Language Group: Lang Data: English – Name: NoteTitleSource Label: Relation Group: SrcInfo Data: https://doi.org/10.1016/j.lanwpc.2025.101524 – Name: DOI Label: DOI Group: ID Data: 10.1016/j.lanwpc.2025.101524 – Name: URL Label: Availability Group: URL Data: https://doi.org/10.1016/j.lanwpc.2025.101524<br />https://ora.ox.ac.uk/objects/uuid:64f20ec8-0aae-465a-b3ec-490196a85d7a – Name: Copyright Label: Rights Group: Cpyrght Data: info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) – Name: AN Label: Accession Number Group: ID Data: edsbas.DE48A50B |
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