Report
A core outcome measurement set (COMS) for research and clinical practice in post COVID-19 condition (long COVID) in adults: an International Delphi Consensus study
| Τίτλος: | A core outcome measurement set (COMS) for research and clinical practice in post COVID-19 condition (long COVID) in adults: an International Delphi Consensus study |
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| Συγγραφείς: | Gorst, SL, Seylanova, N, Harman, N, O'Hara, M, Terwee, CB, Williamson, PR, Needham, DM, Munblit, D, Nicholson, T, Group, P-CS |
| Συνεισφορές: | Olliaro, P, Sigfrid, LA |
| Στοιχεία εκδότη: | SSRN |
| Έτος έκδοσης: | 2025 |
| Συλλογή: | Oxford University Research Archive (ORA) |
| Περιγραφή: | Background: Agreement is lacking regarding which instruments should be used for measurement of a recently-agreed core outcome set (COS) for clinical practice and research in post COVID-19 condition, also known as Long COVID. Methods: A rigorous multi-step consensus study was conducted, including a comprehensive literature review informing a three-round online modified Delphi process followed by an online consensus meeting to finalise measurement instruments for this COS, thereby developing a Core Outcome Measurement Set (COMS). 594 participants from 58 countries spanning six continents, participated in the consensus process. Findings: Consensus was reached for including the 'modified MRC Dyspnea Scale' for measuring the 'Respiratory functioning, symptoms, and conditions' outcome in the COMS. Two outcome measures from the acute COVID-19 COMS were included in this post COVID-19 conditionCOMS, namely 'Time until death' (for the Survival outcome) and 'Recovery Scale for COVID-19' (for the Recovery outcome). Consensus, based on predefined criteria, was not reached for the other 9 outcomes of the COS. However, based on the study results, suggested measurement instruments are provided for 'Fatigue', 'Post-exertion symptoms'; 'Pain', 'Physical function', 'Work/occupational and study changes' and for 'Cardiovascular', 'Nervous system', 'Cognition' and 'Mental' functioning, symptoms and conditions. Interpetation: This international COMS provides a framework for assessing post COVID-19 condition in global clinical research and practice settings. Further evaluation is warranted as new data emerges on the performance of measurement instruments for the COS for this new clinical condition. |
| Τύπος εγγράφου: | report |
| Γλώσσα: | English |
| Relation: | https://doi.org/10.2139/ssrn.4317875 |
| DOI: | 10.2139/ssrn.4317875 |
| Διαθεσιμότητα: | https://doi.org/10.2139/ssrn.4317875 https://ora.ox.ac.uk/objects/uuid:92391915-e835-4618-9c81-f76444797e07 |
| Rights: | info:eu-repo/semantics/openAccess |
| Αριθμός Καταχώρησης: | edsbas.DA522C26 |
| Βάση Δεδομένων: | BASE |
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