Academic Journal

Effectiveness of new antiplatelets in the prevention of recurrent myocardial infarction

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Effectiveness of new antiplatelets in the prevention of recurrent myocardial infarction
Συγγραφείς: Grimaldi-Bensouda, Lamiae, Danchin, Nicolas, Dallongeville, Jean, Falissard, Bruno, Furber, Alain, Cottin, Yves, Bonello, Laurent, Morel, Olivier, Leclercq, Florence, Puymirat, Etienne, Ghanem, Fahmi, Delarche, Nicolas, Benichou, Jacques, Abenhaim, Lucien, the PGRx-Acute Coronary Syndrome Study Group, Aarras, Reda, Abdennbi, Kamel, Akar, Ramzi Abi, Eboule, Corine Aboa, Adda, Michel, Agbessi, Fifa, Agout, Bruno, Ahres, Saïd, Aissou, Linda, Albert, Franck, Alexandre, Joachim, Alies, Alexandre, Allaouchiche, Thierry, Amans, Jean-Marc, Amara, Walid, Amiar, Ahmed, Oster, Gladys Amiel, Amlaiky, Ahmed, Amzallag, Marc, Andrieu, Stephane, Annic, Jean Marie, Ansaldi, Sébastien, Anton, Cyprian, Ardouin, Luc, Armero, Sebastien, Assaf, Abderrahmane, Attali, Pierre, Audebert, Gilles, Auffray, Jean-Luc, Ayrivie, Pierre-Antoine, Azambourg, Jean-Claude, Azzano, Olivier, Baert, Margarita, Baguet, Jean-Philippe, Sepou, Souleyman Bai, Balaire, Xavier, Bali, Laurent, Banayan, Jonathan, Banus, Yves, Baranés, Charles, Barboteu, Michel, Barbou, Franck, Bardoux, Alain, Baron, Nicolas, Barri, Maruan, Olivier, Belhassane, Abdelkader, Bellefleur, Jean Paul, Belliard, Olivier, Bemba, Claudia, Cheikh M Hamed, Laurence Ben, Benchaa, Tewfik, Benhalima, Bouziane, Bensaad, Lamjed, Berland, Jacques, Bermond, Yves, Berneau, Jean Baptiste, Bert-Marcaz, Patrick, Bertora, David, Bertrand, Arnaud, Beurtheret, Sylvain, Biron, Yves, Bizieux, Pierre, Blicq, Elodie, Blondin, Benoit, Bocquillon, Gerard, Bogdanova, Vera, Boige, Emmanuel, Boire, Marie-Thérèse, Bonnet, Jacques, Bontemps, Thierry, Bosle, Sebastien, Bouchlaghem, Khaled Karim, Bouharb, Georges, Boukhsibi, Fatima, Bouleti, Claire, Bourdin, Valerie, Breard, Guillaume, Brunehaut, Myriam, Brunschwig, Claude, Cadoret, Martine, Camenen, Bruno, Canu, Guillaume, Carville, Claudine, Casassus, Frederic, Castera, Rozenn, Causse, Pierre, Cayron, Philippe, Centa, Isabelle, Chabrun, Alexandre, Chalani, Abdeslem, Champagne, Stephane, Chapon, Philippe, Chasseriaud, Warren, Chebahi, Nassim, Chedru, Nicolas, El Bouazzaoui, Saida Cheggour, Chemin, Philippe, Chemmam, Nouredine, Chennouf, Kamal, Cheriaa, Sami, Chiri, Paul, Chisseray-Pramotton, Claire, Chivoret, Guy, Chometon, Frederic, Codjia, Rene, Commeau, Philippe, Corbin, André, Crimizade, Ulun, Crousillat, Bernard, Curjol-Soto, Julie, Dabboura, Adib, Dacunto, Alphonse, Darmon, Bernard, Dary, Patrick, Dascotte, Olivier, Geeter, Guillaume De, Labriolle, Axel De, Ladreit, Roland De, Sauniere, Olivier De, Deaux, Jean Louis, Debonne, Matthieu, Decoulx, Eric, Delamare, Georges, Delfour, Bernard, Delsart, Dominique, Deltreuil, Mathieu, Dematteo, Philippe, Deramchi, Chems Eddine, Derbali, Mohamed, Derycke, Jacques, Palacci, Josyane Devico, Dibon, Olivier, Petit, Katy Didier, Didier, Romain, Djebabra, Abdelkader, Wandji, Charly Djeumen, Doucet, Bernard, Dromnelle, Christophe, Duc, Philippe, Duchatelle, Valerie, Duchemin, Audrey, Dumont, Agathe, Dumortier, Daniel, Dumoulin, Pierre, Dunica, Sylvie, Dupoizat, Arnauld, Biscaye, Catherine Dupont, Dupouy, Patrick, Durandet, Philippe, Duron, Pierre, Dutoit, Laurent, Damen, Fawaz El, Ghelbazouri, Fouad El, Hallak, Abdellatif El, Jabali, Adnan El, Mahmoud, Rami El, Elbaz, Meyer, Elkohen, Mariam, Elmkies, Frederic Gad, Enguehard, Pascale, Epicureo, Alfonso, Orthlieb, Michele Escande, Esna, Ghazaleh, Falquier, Jean-Francois, Farges, Jean Louis, Farza, Abderrazah, Fattah, Fouad, Fauvel, Maurice, Fawaz, Jihad, Fayard, Maxime, Fekhar, Zohir, Feldmann, Israel, Ferrari, Emile, Fhal, Gérard, Fichter, Pierre, Fischbein, Laurent, Flinois, Pascale, Fol, Stéphane, Forest, Eric, Fournier, Christian, Frances, Pierre, Francois, Eric, Frey, Jean-Marc, Friedmann, Reynald, Gacem, Karim, Gacon, Pierre-Henry, Gaillard, Olivier, Garban, Thierry, Garbarz, Eric, Garman, Waddah, Garnier Crussard, Jean-Pierre, Gartenlaub, Olivier, Gavrilina, Tatiana, Gehanne, Audrey, Gehanne, Michel, Geneves, Michel, Georges, Jean-Louis, Ghanem, Nachwan, Gigandet, Catherine, Gil, Jean-Marie, Gillet, Mathieu, Girard-Girod, Aude, Giuliani, Jean-pierre, Goburdhun, Chandrah, Gongora, Antonio, Goralski, Marc, Gourio, Hervé, Greciano, Stéphane, De vallerin, Michel Gudin, Guennioui, Hajar Lahbabi, Guéranger, Pierre, Gugenheim, Anne-Lise, Guillot, Philippe, Guillot, Jean-Paul, Haddad, Véronique, Hamani, Djamel, Hasni, Karim, Helms, Eric, Hersh, Richard, Hess, Sébastien, Hijazi, Bernard, Holeman, Agnès, Honore, Charlotte, Horovitz, Daniel, Houeze, Franck, Hulot, Jean-Sébastien, Hurson, Frédéric, Idir, Messaoud, Ikhlef, Karim, Issa, Adi, Jaboureck, Olivier, Jacob, Gildas, Jazayeri, Saed, Jego, Christophe, Jessen, Philippe, Duval, Marc Jobbe, Joseph, Thierry, Joubert, Jean-Philippe, Jourdain, Patrick, Juste, Rémy, Kabsel, Thomboj Theostyphyl, Kalaaji, Yasser, Karrillon, Gaetan, Kassehin, Didier, Kerebel, Sébastien, Khallaayoune, Ryad, Kioueh, Idriss, Kojfer, Alain, Koujan, Bassel, Kouzez, Mouhammad Mazen, Kozak, Jérome, Kremer, Hélène, Labombarda, Fabien, Roiron, Cécile Lacote, Lacroix, Alain, Lagiewka, Christian, Lamaze, Emmanuel, Lambert, Bruno, Lamy, Eric, Martin, Ingrid Landragin, Lauvergnat, Pascal, Lazizi, Tahar, Franc, Pierre Le, Le Hir, Jean-Michel, Leborgne, Laurent, Lecoq, Guillaume, Lefevre, Didier, Lemiere, Yves, Lesage, Gérard, Lesault, Pierre-Francois, Lhoest, Nicolas, Lize, Yann, Llaty, Pierre, Mansour, Judith Loeb, Long, Jean-Louis, Longere, Philippe, Lorentz, Christian, Louchart, Jean-Christophe, Louembe, Jules, Lounis, Arezki, Lozinguez, Olivier, Bore, Anne Luycx, Lysakowski, Jean-Louis, Bey, Daniel, Mabire, Pascal, Madi, Amine, Magnus, Patricia, Mahdjoub, Benaouda, Muhyjealdeen, Makki, Hamid, Malaterre, Henri, Malbranque, Gregory, Manne, Bernard, Mansour, Michel, Mantoux, Jacques, Manzi, Denis, Silberman, Stéphanie Manzo, Marchand, Arnaud, Maroun, Mounir, Marsaux, Michel, Martelet, Michael, Martin, Olivier, Mateus, Victor, Mazouz, Serge, M’bey, Daniel, Mear, Karine, Mehlal, Fatiha, Mellin, Dominique, Meme, Bruno, Menu, Paul, Meriaux, Francois-Xavier, Mesli, Zoubir, Messas, Nathan, Rivet, Charlotte Mestrallet, Metivier, Marie, Meurice, Thibaud, Meurice, Jonathan, Meurin, Philippe, Mielot, Stéphane, Mielot, Christopher, Mischie, Alexandre, Mlotek, Marcin, Montant, Patrick, Montaut, Daniel, Morillon, Claudine, Moro, Pierre-Julien, Mortada, Saleh, Morvan, Yann, Mouaci, Lakri, Mouallemm, Joseph, Moulla, Maan, Mouret, Jean-Philippe, Mousi, Samer, Muller, Gérard, Muller, Jean-Joseph, Munet, Melchior, Saidi, Lyassine Nait, Nallet, Olivier, Nejman, Marc, Tuan Nguyen, Le Anh, Nguyen, Van Hung, Nitu, Dorian, Nyom, Elisabeth, Ohanessian, Alice, Olariu, Codin, Olivieri, Bernard, Ouguoujil, Azeddine, Ovize, Michel, Pacaud, Didier, Paganelli, Franck, Pankert, Mathieu, Paparoni, Francesco, Pareathumby, Kumaressen, Pariente, Serge, Paule, Philippe, Peroz, Julie, Pichon, Eric, Pinzani, Alain, Piot, Christophe, Piquemal, Renaud, Plantrou, Eric, Pleskof, Alain, Poletti, Grégoire, Ponzio, Jean-Marc, Popescu, Iulia, Poulain, Francois, Pouzet, Bruno, Poyet, Raphael, Quaino, Gonzalo, Rachenne-Barthomeuf, Virginie, Ramanamamonjy, Benjamin, Randriamora, Mamy, Raymond, Patrice, Reins, Pierre, Richalet, Caroline, Roche, Christian, Roche, Nicolas Charles, Roncalli, Jérome, Rosario, Roger, Gretere, Chantal Rosati, Rosey, Guillaume, Roule, Vincent, Rouquette, Philippe, Rousseau, Olivier, Rousseau, Dorine, Roussel, Christophe, Saad, Simon, Blidi, Rim Saad, Saade, Maurice, Sabatier, Rémi, Saint-Pierre, Francois, Salem, Adrien, Salengro, Emmanuel, Saloux, Eric, Samadi, Ali Reza, Sandalian, Alain, Sander, Marc, Pop, Alexandru Sarbu, Sarrau, Virginie, Sayegh, Bachir, Sbaiti, Armand, Scemama, Antony, Schlageter, Patrick, Schoukroun, Gregory, Schraub, Philippe, Selton, Olivier, Seoud, Jamal, Sifaoui, Sylvain, Simonnet, Laurent, Sirbu, Cristina, Sissmann, Joelle, Sokic, Charles, Solanet, Renaud, Soulard, Jean-Pierre, Souyri, Jean, Steg, Philippe Gabriel, Tabet, Stéphane, Tabet, Jean-Yves, Taihi, Samira, Takla, Marc, Tan, Sunhok, Tanguy, Roger, Tanielian, Philippe, Targosz, Frédéric, Tartar, Jean, Teboul, Jacques, Terbah, Mohamed, Terrazzoni, Sébastien, Tessier, Pascal, Thiebaut, Catherine, Tixier, Denix, Toban, Pascal, Tonyiga, Kossi Lolonyo, Trehou, Philippe, Tricot, Olivier, Trouillet, Charlotte, Troussier, Xavier, Tsoumbou, Basile, Tuambilangana, Albert Mudiambi, Uge, Philippe, Unal, Clément, Uzan, Denis, Valero, Franck, Valla, Richard, Vallet, Frédéric, Valy, Yann, Vaquette, Bruno, Varenne, Olivier, Verbrugge, Eric, Villaceque, Marc, Vine, Fabrice, Violet, Thibaud, Vittecoq, Bruno, Wafo, Bernard Charlot, Wanly, Rana, Wazana, Michel, Weingrod, Michel, Werquin, Steve, Wuydin, Xavier, Yadouleton, Cossi Virgile, Yafi, Wael, Zemmour, Gilles
Στοιχεία εκδότη: BMJ Publishing Group Ltd
Έτος έκδοσης: 2018
Συλλογή: HighWire Press (Stanford University)
Θεματικοί όροι: Coronary artery disease
Περιγραφή: Objective To compare ticagrelor and prasugrel with clopidogrel for recurrent fatal and non-fatal myocardial infarction (reMI) in real-life conditions. Methods Case-referent study using the Pharmacoepidemiological General Research eXtension (PGRx)-acute coronary syndrome (ACS) registry. Cases were patients with reMI from a cohort with index ACS or external to the cohort (same sites). Referents from the cohort, without recurrent event, were matched on index ACS type and date, age and sex with reMI cases. Multivariate conditional logistic regression assessed the OR (95% CI) for reMI associated with ticagrelor and prasugrel vs clopidogrel, adjusted for aspirin use and cardiovascular risk factors. Results 1047 cases and 2234 matched referents were included. Compared with clopidogrel, ticagrelor and prasugrel were associated with respective ORs of 0.65 (95% CI 0.52 to 0.81) and 0.71 (95% CI 0.53 to 0.96) for reMI occurrence. ORs for ticagrelor and prasugrel vs clopidogrel were: 0.50 (95% CI 0.38 to 0.67) and 0.66 (95% CI 0.45 to 0.95), 0.39 (95% CI 0.24 to 0.62) and 0.44 (95% CI 0.26 to 0.75), 0.63 (95% CI 0.43 to 0.92) and 1.20 (95% CI 0.69 to 2.07), 1.11 (95% CI 0.72 to 1.72) and 0.82 (95% CI 0.44 to 1.54) when index ACS was a first MI, a first ST-elevated MI (STEMI), a first non-STEMI and a recurrent ACS, respectively, and 0.63 (95% CI 0.45 to 0.87) and 0.77 (95% CI 0.41 to 1.45) for patients aged ≥70 years. Conclusions This real-world study showed a significant reduction of reMI with new antiplatelets compared with clopidogrel, ticagrelor being associated with a greater decrease of risk notably for first, either STEMI or non-STEMI. The larger magnitude of effect may be attributed to potential residual confounding or higher effectiveness compared with efficacy reported in trials (EMA Post Authorisation Study Registry Number EUPAS5905).
Τύπος εγγράφου: text
Περιγραφή αρχείου: text/html
Γλώσσα: English
Relation: http://heart.bmj.com/cgi/content/short/104/19/1583; http://dx.doi.org/10.1136/heartjnl-2017-312534
DOI: 10.1136/heartjnl-2017-312534
Διαθεσιμότητα: http://heart.bmj.com/cgi/content/short/104/19/1583
https://doi.org/10.1136/heartjnl-2017-312534
Rights: Copyright (C) 2018, BMJ Publishing Group Ltd
Αριθμός Καταχώρησης: edsbas.D05E5574
Βάση Δεδομένων: BASE