DataSheet1_Skin temperature influence on transcutaneous carbon dioxide (CO2) conductivity and skin blood flow in healthy human subjects at the arm and wrist.PDF

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: DataSheet1_Skin temperature influence on transcutaneous carbon dioxide (CO2) conductivity and skin blood flow in healthy human subjects at the arm and wrist.PDF
Συγγραφείς: Emmanuel Dervieux, François Guerrero, Wilfried Uhring, Marie-Agnès Giroux-Metgès, Michaël Théron
Έτος έκδοσης: 2024
Συλλογή: Frontiers: Figshare
Θεματικοί όροι: Physiology, Exercise Physiology, Nutritional Physiology, Reproduction, Cell Physiology, Systems Physiology, Animal Physiology - Biophysics, Animal Physiology - Cell, Animal Physiology - Systems, Comparative Physiology, Physiology not elsewhere classified, carbon dioxide, ptCO2, tcpCO2, transcutaneous, exhalation rate, diffusion, blood flow, hyperaemia
Περιγραφή: Objective: present transcutaneous carbon dioxide (CO 2 )—tcpCO 2 —monitors suffer from limitations which hamper their widespread use, and call for a new tcpCO 2 measurement technique. However, the progress in this area is hindered by the lack of knowledge in transcutaneous CO 2 diffusion. To address this knowledge gap, this study focuses on investigating the influence of skin temperature on two key skin properties: CO 2 permeability and skin blood flow. Methods: a monocentric prospective exploratory study including 40 healthy adults was undertaken. Each subject experienced a 90 min visit split into five 18 min sessions at different skin temperatures—Non-Heated (NH), 35, 38, 41, and 44°C. At each temperature, custom sensors measured transcutaneous CO 2 conductivity and exhalation rate at the arm and wrist, while Laser Doppler Flowmetry (LDF) assessed skin blood flow at the arm. Results: the three studied metrics sharply increased with rising skin temperature. Mean values increased from the NH situation up to 44°C from 4.03 up to 8.88 and from 2.94 up to 8.11 m·s −1 for skin conductivity, and from 80.4 up to 177.5 and from 58.7 up to 162.3 cm 3 ·m −2 ·h −1 for exhalation rate at the arm and wrist, respectively. Likewise, skin blood flow increased elevenfold for the same temperature increase. Of note, all metrics already augmented significantly in the 35–38°C skin temperature range, which may be reached without active heating—i.e. only using a warm clothing. Conclusion: these results are extremely encouraging for the development of next-generation tcpCO 2 sensors. Indeed, the moderate increase (× 2) in skin conductivity from NH to 44°C tends to indicate that heating the skin is not critical from a response time point of view, i.e. little to no skin heating would only result in a doubled sensor response time in the worst case, compared to a maximal heating at 44°C. Crucially, a skin temperature within the 35–38°C range already sharply increases the skin blood flow, suggesting that tcpCO 2 correlates well with the ...
Τύπος εγγράφου: dataset
Γλώσσα: unknown
Relation: https://figshare.com/articles/dataset/DataSheet1_Skin_temperature_influence_on_transcutaneous_carbon_dioxide_CO2_conductivity_and_skin_blood_flow_in_healthy_human_subjects_at_the_arm_and_wrist_PDF/25048190
DOI: 10.3389/fphys.2023.1293752.s001
Διαθεσιμότητα: https://doi.org/10.3389/fphys.2023.1293752.s001
https://figshare.com/articles/dataset/DataSheet1_Skin_temperature_influence_on_transcutaneous_carbon_dioxide_CO2_conductivity_and_skin_blood_flow_in_healthy_human_subjects_at_the_arm_and_wrist_PDF/25048190
Rights: CC BY 4.0
Αριθμός Καταχώρησης: edsbas.CA396A81
Βάση Δεδομένων: BASE