Academic Journal
Quantitative analysis of hemodynamics of congested island flaps under leech therapy
| Τίτλος: | Quantitative analysis of hemodynamics of congested island flaps under leech therapy |
|---|---|
| Συγγραφείς: | Kashiwagi, Keisuke, Hashimoto, Ichiro, Abe, Yoshiro, Kotsu, Kunio, Yamano, Masahiro, Nakanishi, Hideki |
| Έτος έκδοσης: | 2017 |
| Συλλογή: | Tokushima University Institutional Repository / 徳島大学機関リポジトリ |
| Θεματικοί όροι: | leech therapy, congestion, island flap, microcirculation, TcPO2 and TcPCO2 monitoring |
| Περιγραφή: | Background A congested flap is a good indication for leech therapy. However, determining the appropriate number of leeches as well as the appropriate application time in clinical cases is difficult. We analyzed hemodynamics in rabbit island flaps under leech therapy to find a suitable clinical procedure for determining the appropriate number of leeches to be used and the duration of therapy. Methods Island flaps were raised in 35 rabbit ears, and congestion was induced by venous clamping. Treatment involved use of 1 or 3 leeches and was begun 60 minutes after venous occlusion. Flaps were examined for area of surviving tissue, alterations in transcutaneous oxygen and carbon dioxide tension (TcPO2 and TcPCO2), and flow volume. Arteriole and venule diameters and flow velocities were examined microscopically. Results Flap survival area in the 3-leech therapy group was significantly larger than the 1-leech therapy group and the control group. With 3- leech therapy, TcPCO2 decreased significantly, as did arteriole and venule diameters. After clamp release, TcPCO2 and venule diameter continued to decrease in this group, and flow velocity increased significantly. Conclusions Leech therapy may salvage compromised flaps by replacing congested blood with new arterial blood and thus maintaining flap viability. TcPO2 and TcPCO2 monitoring may help evaluate the therapeutic effect and determine the appropriate number of leeches to apply and the duration of therapy. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| ISSN: | 13431420 |
| Relation: | http://repo.lib.tokushima-u.ac.jp/files/public/10/106359/20170929145100939535/LID201507305001.pdf; AA11166929 |
| Διαθεσιμότητα: | http://repo.lib.tokushima-u.ac.jp/106359 |
| Αριθμός Καταχώρησης: | edsbas.C904493 |
| Βάση Δεδομένων: | BASE |
| FullText | Text: Availability: 0 CustomLinks: – Url: http://repo.lib.tokushima-u.ac.jp/106359# Name: EDS - BASE (ns324271) Category: fullText Text: View record from BASE – Url: https://resolver.ebsco.com/c/fiv2js/result?sid=EBSCO:edsbas&genre=article&issn=13431420&ISBN=&volume=&issue=&date=20170101&spage=&pages=&title=Quantitative analysis of hemodynamics of congested island flaps under leech therapy&atitle=Quantitative%20analysis%20of%20hemodynamics%20of%20congested%20island%20flaps%20under%20leech%20therapy&aulast=Kashiwagi%2C%20Keisuke&id=DOI: Name: Full Text Finder (for New FTF UI) (ns324271) Category: fullText Text: Full Text Finder MouseOverText: Full Text Finder |
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| Header | DbId: edsbas DbLabel: BASE An: edsbas.C904493 RelevancyScore: 795 AccessLevel: 3 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 794.807434082031 |
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| Items | – Name: Title Label: Title Group: Ti Data: Quantitative analysis of hemodynamics of congested island flaps under leech therapy – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kashiwagi%2C+Keisuke%22">Kashiwagi, Keisuke</searchLink><br /><searchLink fieldCode="AR" term="%22Hashimoto%2C+Ichiro%22">Hashimoto, Ichiro</searchLink><br /><searchLink fieldCode="AR" term="%22Abe%2C+Yoshiro%22">Abe, Yoshiro</searchLink><br /><searchLink fieldCode="AR" term="%22Kotsu%2C+Kunio%22">Kotsu, Kunio</searchLink><br /><searchLink fieldCode="AR" term="%22Yamano%2C+Masahiro%22">Yamano, Masahiro</searchLink><br /><searchLink fieldCode="AR" term="%22Nakanishi%2C+Hideki%22">Nakanishi, Hideki</searchLink> – Name: DatePubCY Label: Publication Year Group: Date Data: 2017 – Name: Subset Label: Collection Group: HoldingsInfo Data: Tokushima University Institutional Repository / 徳島大学機関リポジトリ – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22leech+therapy%22">leech therapy</searchLink><br /><searchLink fieldCode="DE" term="%22congestion%22">congestion</searchLink><br /><searchLink fieldCode="DE" term="%22island+flap%22">island flap</searchLink><br /><searchLink fieldCode="DE" term="%22microcirculation%22">microcirculation</searchLink><br /><searchLink fieldCode="DE" term="%22TcPO2+and+TcPCO2+monitoring%22">TcPO2 and TcPCO2 monitoring</searchLink> – Name: Abstract Label: Description Group: Ab Data: Background A congested flap is a good indication for leech therapy. However, determining the appropriate number of leeches as well as the appropriate application time in clinical cases is difficult. We analyzed hemodynamics in rabbit island flaps under leech therapy to find a suitable clinical procedure for determining the appropriate number of leeches to be used and the duration of therapy. Methods Island flaps were raised in 35 rabbit ears, and congestion was induced by venous clamping. Treatment involved use of 1 or 3 leeches and was begun 60 minutes after venous occlusion. Flaps were examined for area of surviving tissue, alterations in transcutaneous oxygen and carbon dioxide tension (TcPO2 and TcPCO2), and flow volume. Arteriole and venule diameters and flow velocities were examined microscopically. Results Flap survival area in the 3-leech therapy group was significantly larger than the 1-leech therapy group and the control group. With 3- leech therapy, TcPCO2 decreased significantly, as did arteriole and venule diameters. After clamp release, TcPCO2 and venule diameter continued to decrease in this group, and flow velocity increased significantly. Conclusions Leech therapy may salvage compromised flaps by replacing congested blood with new arterial blood and thus maintaining flap viability. TcPO2 and TcPCO2 monitoring may help evaluate the therapeutic effect and determine the appropriate number of leeches to apply and the duration of therapy. – Name: TypeDocument Label: Document Type Group: TypDoc Data: article in journal/newspaper – Name: Language Label: Language Group: Lang Data: English – Name: ISSN Label: ISSN Group: ISSN Data: 13431420 – Name: NoteTitleSource Label: Relation Group: SrcInfo Data: http://repo.lib.tokushima-u.ac.jp/files/public/10/106359/20170929145100939535/LID201507305001.pdf; AA11166929 – Name: URL Label: Availability Group: URL Data: http://repo.lib.tokushima-u.ac.jp/106359 – Name: AN Label: Accession Number Group: ID Data: edsbas.C904493 |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.C904493 |
| RecordInfo | BibRecord: BibEntity: Languages: – Text: English Subjects: – SubjectFull: leech therapy Type: general – SubjectFull: congestion Type: general – SubjectFull: island flap Type: general – SubjectFull: microcirculation Type: general – SubjectFull: TcPO2 and TcPCO2 monitoring Type: general Titles: – TitleFull: Quantitative analysis of hemodynamics of congested island flaps under leech therapy Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kashiwagi, Keisuke – PersonEntity: Name: NameFull: Hashimoto, Ichiro – PersonEntity: Name: NameFull: Abe, Yoshiro – PersonEntity: Name: NameFull: Kotsu, Kunio – PersonEntity: Name: NameFull: Yamano, Masahiro – PersonEntity: Name: NameFull: Nakanishi, Hideki IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 13431420 – Type: issn-locals Value: edsbas |
| ResultId | 1 |