Academic Journal
An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation
| Title: | An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation |
|---|---|
| Authors: | Smith, Moray, Kaur, Amanpreet, Singh, Vikrant, Jones, John T, Hein, Ingo |
| Source: | Smith, M, Kaur, A, Singh, V, Jones, J T & Hein, I 2026, 'An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation', G3: Genes, Genomes, Genetics, vol. 16, no. 6. https://doi.org/10.1093/g3journal/jkag089 |
| Publication Year: | 2026 |
| Collection: | Discovery - University of Dundee Online Publications |
| Subject Terms: | Solanum verrucosum, centromere, disease resistance, genome assembly, methylation, self-compatibility, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1311, name=Genetics, /dk/atira/pure/subjectarea/asjc/2700/2716, name=Genetics(clinical) |
| Description: | Solanum verrucosum is a wild diploid potato species notable for carrying the uncharacterized Rpi-ver1 gene conferring resistance to Phytophthora infestans, possessing unusually structured centromeres, and exhibiting the rare trait of self-compatibility, the genetic basis of which remains unknown. Here, we present a high-quality genome assembly and annotation of S. verrucosum accession CPC54. A comprehensive inventory of resistance genes is provided, and candidate genes for Rpi-ver1 are identified through remapping approaches. The sequence and epigenetic landscape of centromeres are resolved, revealing a mosaic of repeatless and repetitive domains. These centromeres consist of tandem arrays of kilobase-sized repeats, some of which show signatures of transposable element origin. Specific subfamilies of CRM and Tekay elements appear to have adapted to centromeric regions. The basis of self-compatibility in S. verrucosum is investigated with respect to the S-RNase gene, which is found to be present and intact but expressed at very low levels. Notably, upstream insertions of transposable elements are present that may interfere with its expression. |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 2160-1836 |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/41934284; info:eu-repo/semantics/altIdentifier/pissn/2160-1836 |
| DOI: | 10.1093/g3journal/jkag089 |
| Availability: | https://discovery.dundee.ac.uk/en/publications/3609c92b-315e-4103-8537-d277aca2ebf4 https://doi.org/10.1093/g3journal/jkag089 https://discovery.dundee.ac.uk/ws/files/172801250/jkag089.pdf |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.C4DF108E |
| Database: | BASE |
Be the first to leave a comment!