Academic Journal
Ambient PM2.5, O3, and NO2 exposures and associations with mortality over 16 years of follow-up in the canadian census health and environment cohort (CanCHEC)
| Τίτλος: | Ambient PM2.5, O3, and NO2 exposures and associations with mortality over 16 years of follow-up in the canadian census health and environment cohort (CanCHEC) |
|---|---|
| Συγγραφείς: | Crouse, D.L. (Dan L.), Peters, P. (Paul A.), Hystad, P. (Perry), Brook, J.R. (Jeffrey R.), van Donkelaar, A. (Aaron), Martin, R.V. (Randall V.), Villeneuve, P. (Paul), Jerrett, M. (Michael), Goldberg, M.S. (Mark S.), Arden Pope, C. (C.), Brauer, M. (Michael), Brook, R.D. (Robert D.), Robichaud, A. (Alain), Menard, R. (Richard), Burnett, R.T. (Richard T.) |
| Πηγή: | Environmental Health Perspectives vol. 123 no. 11, pp. 1180-1186 |
| Έτος έκδοσης: | 2015 |
| Συλλογή: | Carleton University's Institutional Repository |
| Περιγραφή: | Background: Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up. Objective: We investigated associations between cause-specific mortality and ambient concentrations of fine particulate matter (≤ 2.5 μm; PM2.5), ozone (O3), and nitrogen dioxide (NO2) in a national cohort of about 2.5 million Canadians. Methods: We assigned estimates of annual concentrations of these pollutants to the residential postal codes of subjects for each year during 16 years of follow-up. Historical tax data allowed us to track subjects’ residential postal code annually. We estimated hazard ratios (HRs) for each pollutant separately and adjusted for the other pollutants. We also estimated the product of the three HRs as a measure of the cumulative association with mortality for several causes of death for an increment of the mean minus the 5th percentile of each pollutant: 5.0 μg/m3 for PM2.5, 9.5 ppb for O3, and 8.1 ppb for NO2. Results: PM2.5, O3, and NO2 were associated with nonaccidental and cause-specific mortality in single-pollutant models. Exposure to PM2.5 alone was not sufficient to fully characterize the toxicity of the atmospheric mix or to fully explain the risk of mortality associated with exposure to ambient pollution. Assuming additive associations, the estimated HR for nonaccidental mortality corresponding to a change in exposure from the mean to the 5th percentile for all three pollutants together was 1.075 (95% CI: 1.067, 1.084). Accounting for residential mobility had only a limited impact on the association between mortality and PM2.5 and O3, but increased associa-tions with NO2. conclusions: In this large, national-level cohort, we found positive associations between several common causes of death and exposure |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| Relation: | https://ir.library.carleton.ca/pub/22560 |
| DOI: | 10.1289/ehp.1409276 |
| Διαθεσιμότητα: | https://ir.library.carleton.ca/pub/22560 https://doi.org/10.1289/ehp.1409276 |
| Rights: | info:eu-repo/semantics/openAccess |
| Αριθμός Καταχώρησης: | edsbas.B9BA1548 |
| Βάση Δεδομένων: | BASE |
| FullText | Text: Availability: 0 CustomLinks: – Url: https://ir.library.carleton.ca/pub/22560# Name: EDS - BASE (ns324271) Category: fullText Text: View record from BASE |
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| Items | – Name: Title Label: Title Group: Ti Data: Ambient PM2.5, O3, and NO2 exposures and associations with mortality over 16 years of follow-up in the canadian census health and environment cohort (CanCHEC) – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Crouse%2C+D%2EL%2E+%28Dan+L%2E%29%22">Crouse, D.L. (Dan L.)</searchLink><br /><searchLink fieldCode="AR" term="%22Peters%2C+P%2E+%28Paul+A%2E%29%22">Peters, P. (Paul A.)</searchLink><br /><searchLink fieldCode="AR" term="%22Hystad%2C+P%2E+%28Perry%29%22">Hystad, P. (Perry)</searchLink><br /><searchLink fieldCode="AR" term="%22Brook%2C+J%2ER%2E+%28Jeffrey+R%2E%29%22">Brook, J.R. (Jeffrey R.)</searchLink><br /><searchLink fieldCode="AR" term="%22van+Donkelaar%2C+A%2E+%28Aaron%29%22">van Donkelaar, A. (Aaron)</searchLink><br /><searchLink fieldCode="AR" term="%22Martin%2C+R%2EV%2E+%28Randall+V%2E%29%22">Martin, R.V. (Randall V.)</searchLink><br /><searchLink fieldCode="AR" term="%22Villeneuve%2C+P%2E+%28Paul%29%22">Villeneuve, P. (Paul)</searchLink><br /><searchLink fieldCode="AR" term="%22Jerrett%2C+M%2E+%28Michael%29%22">Jerrett, M. (Michael)</searchLink><br /><searchLink fieldCode="AR" term="%22Goldberg%2C+M%2ES%2E+%28Mark+S%2E%29%22">Goldberg, M.S. (Mark S.)</searchLink><br /><searchLink fieldCode="AR" term="%22Arden+Pope%2C+C%2E+%28C%2E%29%22">Arden Pope, C. (C.)</searchLink><br /><searchLink fieldCode="AR" term="%22Brauer%2C+M%2E+%28Michael%29%22">Brauer, M. (Michael)</searchLink><br /><searchLink fieldCode="AR" term="%22Brook%2C+R%2ED%2E+%28Robert+D%2E%29%22">Brook, R.D. (Robert D.)</searchLink><br /><searchLink fieldCode="AR" term="%22Robichaud%2C+A%2E+%28Alain%29%22">Robichaud, A. (Alain)</searchLink><br /><searchLink fieldCode="AR" term="%22Menard%2C+R%2E+%28Richard%29%22">Menard, R. (Richard)</searchLink><br /><searchLink fieldCode="AR" term="%22Burnett%2C+R%2ET%2E+%28Richard+T%2E%29%22">Burnett, R.T. (Richard T.)</searchLink> – Name: TitleSource Label: Source Group: Src Data: Environmental Health Perspectives vol. 123 no. 11, pp. 1180-1186 – Name: DatePubCY Label: Publication Year Group: Date Data: 2015 – Name: Subset Label: Collection Group: HoldingsInfo Data: Carleton University's Institutional Repository – Name: Abstract Label: Description Group: Ab Data: Background: Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up. Objective: We investigated associations between cause-specific mortality and ambient concentrations of fine particulate matter (≤ 2.5 μm; PM2.5), ozone (O3), and nitrogen dioxide (NO2) in a national cohort of about 2.5 million Canadians. Methods: We assigned estimates of annual concentrations of these pollutants to the residential postal codes of subjects for each year during 16 years of follow-up. Historical tax data allowed us to track subjects’ residential postal code annually. We estimated hazard ratios (HRs) for each pollutant separately and adjusted for the other pollutants. We also estimated the product of the three HRs as a measure of the cumulative association with mortality for several causes of death for an increment of the mean minus the 5th percentile of each pollutant: 5.0 μg/m3 for PM2.5, 9.5 ppb for O3, and 8.1 ppb for NO2. Results: PM2.5, O3, and NO2 were associated with nonaccidental and cause-specific mortality in single-pollutant models. Exposure to PM2.5 alone was not sufficient to fully characterize the toxicity of the atmospheric mix or to fully explain the risk of mortality associated with exposure to ambient pollution. Assuming additive associations, the estimated HR for nonaccidental mortality corresponding to a change in exposure from the mean to the 5th percentile for all three pollutants together was 1.075 (95% CI: 1.067, 1.084). Accounting for residential mobility had only a limited impact on the association between mortality and PM2.5 and O3, but increased associa-tions with NO2. conclusions: In this large, national-level cohort, we found positive associations between several common causes of death and exposure – Name: TypeDocument Label: Document Type Group: TypDoc Data: article in journal/newspaper – Name: Language Label: Language Group: Lang Data: English – Name: NoteTitleSource Label: Relation Group: SrcInfo Data: https://ir.library.carleton.ca/pub/22560 – Name: DOI Label: DOI Group: ID Data: 10.1289/ehp.1409276 – Name: URL Label: Availability Group: URL Data: https://ir.library.carleton.ca/pub/22560<br />https://doi.org/10.1289/ehp.1409276 – Name: Copyright Label: Rights Group: Cpyrght Data: info:eu-repo/semantics/openAccess – Name: AN Label: Accession Number Group: ID Data: edsbas.B9BA1548 |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.B9BA1548 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1289/ehp.1409276 Languages: – Text: English Titles: – TitleFull: Ambient PM2.5, O3, and NO2 exposures and associations with mortality over 16 years of follow-up in the canadian census health and environment cohort (CanCHEC) Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Crouse, D.L. (Dan L.) – PersonEntity: Name: NameFull: Peters, P. (Paul A.) – PersonEntity: Name: NameFull: Hystad, P. (Perry) – PersonEntity: Name: NameFull: Brook, J.R. (Jeffrey R.) – PersonEntity: Name: NameFull: van Donkelaar, A. (Aaron) – PersonEntity: Name: NameFull: Martin, R.V. (Randall V.) – PersonEntity: Name: NameFull: Villeneuve, P. (Paul) – PersonEntity: Name: NameFull: Jerrett, M. (Michael) – PersonEntity: Name: NameFull: Goldberg, M.S. (Mark S.) – PersonEntity: Name: NameFull: Arden Pope, C. (C.) – PersonEntity: Name: NameFull: Brauer, M. (Michael) – PersonEntity: Name: NameFull: Brook, R.D. (Robert D.) – PersonEntity: Name: NameFull: Robichaud, A. (Alain) – PersonEntity: Name: NameFull: Menard, R. (Richard) – PersonEntity: Name: NameFull: Burnett, R.T. (Richard T.) IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2015 Identifiers: – Type: issn-locals Value: edsbas – Type: issn-locals Value: edsbas.oa Titles: – TitleFull: Environmental Health Perspectives vol. 123 no. 11, pp. 1180-1186 Type: main |
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