Academic Journal
Prognostic Variation Among Very High-Risk and High-Risk Individuals With Atherosclerotic Cardiovascular Disease
| Title: | Prognostic Variation Among Very High-Risk and High-Risk Individuals With Atherosclerotic Cardiovascular Disease |
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| Authors: | Mok, Y., Ballew, S.H., Stacey, R.B., Rossi, J., Koton, S., Kucharska-Newton, A.M., Chang, P.P., Coresh, J., Rosamond, W., Matsushita, K. |
| Source: | Journal of the American College of Cardiology, 76(3) |
| Publisher Information: | Elsevier USA |
| Publication Year: | 2020 |
| Collection: | Carolina Digital Repository (UNC - University of North Carolina) |
| Subject Terms: | prognosis, Risk Assessment, procedures, cardiovascular risk, heart infarction, Humans, Global Health, priority journal, brain ischemia, all cause mortality, clinical outcome, hazard ratio, male, Aged, practice guideline, Female, antilipemic agent, Middle Aged, Atherosclerosis, major clinical study, risk factor, Risk Factors, controlled study, heart failure, cardiovascular mortality, incidence, coronary artery atherosclerosis, human, Hypolipidemic Agents, Letter |
| Description: | Given the availability of an effective but expensive lipid-lowering medication, proprotein convertase subtilisin/kexin type 9 inhibitors, the American Heart Association and the American College of Cardiology 2018 cholesterol guideline introduced a new classification of “very high-risk” (i.e., multiple major atherosclerotic cardiovascular diseases [ASCVDs] or a major ASCVD þ multiple high-risk conditions) versus “high-risk” for patients with prior ASCVD. A few recent studies reported risk variation within very high-risk ASCVD, with multiple ASCVDs conferring higher risk than 1 ASCVD þ $2 high-risk conditions. However, these studies did not evaluate whether the constellation of high-risk conditions in 1 ASCVD may equate to the risk of multiple ASCVDs or whether the new classification has implications for heart failure. |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | https://cdr.lib.unc.edu/downloads/b85160644?file=thumbnail; https://cdr.lib.unc.edu/downloads/b85160644 |
| DOI: | 10.17615/mg4n-x653 |
| Availability: | https://doi.org/10.17615/mg4n-x653 https://cdr.lib.unc.edu/downloads/b85160644?file=thumbnail https://cdr.lib.unc.edu/downloads/b85160644 |
| Accession Number: | edsbas.B0C72143 |
| Database: | BASE |
| DOI: | 10.17615/mg4n-x653 |
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