Academic Journal
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
| Τίτλος: | Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c |
|---|---|
| Συγγραφείς: | Zhou, B, Sheffer, KE, Bennett, JE, Gregg, EW, Danaei, G, Singleton, RK, Shaw, JE, Mishra, A, Lhoste, VPF, Carrillo-Larco, RM, Kengne, AP, Phelps, NH, Heap, RA, Rayner, AW, Stevens, GA, Paciorek, CJ, Riley, LM, Cowan, MJ, Savin, S, Vander Hoorn, S, Lu, Y, Pavkov, ME, Imperatore, G, Aguilar-Salinas, CA, Ahmad, NA, Anjana, RM, Davletov, K, Farzadfar, F, González-Villalpando, C, Khang, YH, Kim, HC, Laatikainen, T, Laxmaiah, A, Mbanya, JCN, Narayan, KMV, Ramachandran, A, Wade, AN, Zdrojewski, T, Abbasi-Kangevari, M, Rahim, HFA, Abu-Rmeileh, NM, Adambekov, S, Adams, RJ, Aekplakorn, W, Agdeppa, IA, Aghazadeh-Attari, J, Agyemang, C, Ahmadi, A, Ahmadi, N, Ahmed, SH, Ajlouni, K, Al-Hinai, H, Al-Lahou, B, Al-Lawati, JA, Asfoor, DA, Al Qaoud, NM, Alarouj, M, AlBuhairan, F, AlDhukair, S, Aldwairji, MA, Ali, MM, Alinezhad, F, Alkandari, A, Alomirah, HF, Aly, E, Amarapurkar, DN, Andersen, LB, Anderssen, SA, Andrade, DS, Ansari-Moghaddam, A, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Aryal, KK, Assah, FK, Assembekov, B, Auvinen, J, Avdičová, M, Azad, K, Azimi-Nezhad, M, Azizi, F, Bacopoulou, F, Balakrishna, N, Bamoshmoosh, M, Banach, M, Bandosz, P, Banegas, JR, Barbagallo, CM, Barceló, A, Baretić, M, Barrera, L, Basit, A, Batieha, AM, Batista, AP, Baur, LA, Belavendra, A, Ben Romdhane, H, Benet, M, Berkinbayev, S, Sundstorm, Johan, Simons, Leon, Woodward, Mark |
| Πηγή: | urn:ISSN:1078-8956 ; urn:ISSN:1546-170X ; Nature Medicine, 29, 11, 2885-2901 |
| Στοιχεία εκδότη: | Springer Nature |
| Έτος έκδοσης: | 2023 |
| Συλλογή: | UNSW Sydney (The University of New South Wales): UNSWorks |
| Θεματικοί όροι: | 4202 Epidemiology, 32 Biomedical and Clinical Sciences, 42 Health Sciences, Diabetes, 4.2 Evaluation of markers and technologies, Metabolic and endocrine, Humans, Glycated Hemoglobin, Glucose, Blood Glucose, Prevalence, Diabetes Mellitus, Fasting, NCD Risk Factor Collaboration (NCD-RisC), anzsrc-for: 4202 Epidemiology, anzsrc-for: 32 Biomedical and Clinical Sciences, anzsrc-for: 42 Health Sciences, anzsrc-for: 11 Medical and Health Sciences |
| Περιγραφή: | Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | unknown |
| Relation: | https://hdl.handle.net/1959.4/unsworks_85619 |
| DOI: | 10.1038/s41591-023-02610-2 |
| Διαθεσιμότητα: | https://hdl.handle.net/1959.4/unsworks_85619 https://unsworks.unsw.edu.au/bitstreams/6d555381-8a0e-44d3-98ae-38415a40c88b/download https://doi.org/10.1038/s41591-023-02610-2 |
| Rights: | open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY ; https://creativecommons.org/licenses/by/4.0/ ; free_to_read |
| Αριθμός Καταχώρησης: | edsbas.A56C21B8 |
| Βάση Δεδομένων: | BASE |
| FullText | Text: Availability: 0 CustomLinks: – Url: https://hdl.handle.net/1959.4/unsworks_85619# Name: EDS - BASE (ns324271) Category: fullText Text: View record from BASE |
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| IllustrationInfo | |
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term="%22anzsrc-for%3A+32+Biomedical+and+Clinical+Sciences%22">anzsrc-for: 32 Biomedical and Clinical Sciences</searchLink><br /><searchLink fieldCode="DE" term="%22anzsrc-for%3A+42+Health+Sciences%22">anzsrc-for: 42 Health Sciences</searchLink><br /><searchLink fieldCode="DE" term="%22anzsrc-for%3A+11+Medical+and+Health+Sciences%22">anzsrc-for: 11 Medical and Health Sciences</searchLink> – Name: Abstract Label: Description Group: Ab Data: Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance. – Name: TypeDocument Label: Document Type Group: TypDoc Data: article in journal/newspaper – Name: Format Label: File Description Group: SrcInfo Data: application/pdf – Name: Language Label: Language Group: Lang Data: unknown – Name: NoteTitleSource Label: Relation Group: SrcInfo Data: https://hdl.handle.net/1959.4/unsworks_85619 – Name: DOI Label: DOI Group: ID Data: 10.1038/s41591-023-02610-2 – Name: URL Label: Availability Group: URL Data: https://hdl.handle.net/1959.4/unsworks_85619<br />https://unsworks.unsw.edu.au/bitstreams/6d555381-8a0e-44d3-98ae-38415a40c88b/download<br />https://doi.org/10.1038/s41591-023-02610-2 – Name: Copyright Label: Rights Group: Cpyrght Data: open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY ; https://creativecommons.org/licenses/by/4.0/ ; free_to_read – Name: AN Label: Accession Number Group: ID Data: edsbas.A56C21B8 |
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urn:ISSN:1078-8956 ; urn:ISSN:1546-170X ; Nature Medicine, 29, 11, 2885-2901 Type: main |
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