Academic Journal
Predictive value of the PRAETORIAN score for defibrillation test success in patients with subcutaneous ICD: A subanalysis of the PRAETORIAN-DFT trial
| Τίτλος: | Predictive value of the PRAETORIAN score for defibrillation test success in patients with subcutaneous ICD: A subanalysis of the PRAETORIAN-DFT trial |
|---|---|
| Συγγραφείς: | Knops, RE, El-Chami, MF, Marquie, C, Nordbeck, P, Quast, AFBE, Tilz, RR, Brouwer, TF, Lambiase, PD, Cassidy, CJ, Boersma, LVA, Burke, MC, Pepplinkhuizen, S, de Veld, JA, de Weger, A, Bracke, FALE, Manyam, H, Probst, V, Betts, TR, Bijsterveld, NR, Defaye, P, Demming, T, Elders, J, Field, DC, Ghani, A, Golovchiner, G, de Jong, JSSG, Lewis, N, Marijon, E, Martin, CA, Miller, MA, Shaik, NA, van der Stuijt, W, Kuschyk, J, Olde Nordkamp, LRA, Arya, A, Borger van der Burg, AE, Boveda, S, van Doorn, DJ, Glikson, M, Kaiser, L, Maass, AH, van Woerkens, LJPM, Zaidi, A, Wilde, AAM, Smeding, L |
| Πηγή: | Heart Rhythm (2024) (In press). |
| Στοιχεία εκδότη: | Elsevier BV |
| Έτος έκδοσης: | 2024 |
| Συλλογή: | University College London: UCL Discovery |
| Θεματικοί όροι: | Defibrillation testing, PRAETORIAN score, Subcutaneous ICD, Transvenous ICD, Ventricular arrhythmia |
| Περιγραφή: | Background: The PRAETORIAN score estimates the risk of failure of subcutaneous implantable cardioverter-defibrillator (S-ICD) therapy by using generator and lead positioning on bidirectional chest radiographs. The PRospective randomized compArative trial of subcutanEous implanTable cardiOverter-defibrillatoR ImplANtation with and without DeFibrillation Testing (PRAETORIAN-DFT) investigates whether PRAETORIAN score calculation is noninferior to defibrillation testing (DFT) with regard to first shock efficacy in spontaneous events. Objective: This prespecified subanalysis assessed the predictive value of the PRAETORIAN score for defibrillation success in induced ventricular arrhythmias. Methods: This multicenter investigator-initiated trial randomized 965 patients between DFT and PRAETORIAN score calculation after de novo S-ICD implantation. Successful DFT was defined as conversion of induced ventricular arrhythmia in <5 seconds from shock delivery within 2 attempts. Bidirectional chest radiographs were obtained after implantation. The predictive value of the PRAETORIAN score for DFT success was calculated for patients in the DFT arm. Results: In total, 482 patients were randomized to undergo DFT. Of these patients, 457 (95%) underwent DFT according to protocol, of whom 445 (97%) had successful DFT and 12 (3%) had failed DFT. A PRAETORIAN score of ≥90 had a positive predictive value of 25% for failed DFT, and a PRAETORIAN score of <90 had a negative predictive value of 99% for successful DFT. A PRAETORIAN score of ≥90 was the strongest independent predictor for failed DFT (odds ratio 33.77; confidence interval 6.13–279.95; P <.001). Conclusion: A PRAETORIAN score of <90 serves as a reliable indicator for DFT success in patients with S-ICD, and a PRAETORIAN score of ≥90 is a strong predictor for DFT failure. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10190518/ |
| Διαθεσιμότητα: | https://discovery.ucl.ac.uk/id/eprint/10190518/1/1-s2.0-S1547527124001152-main.pdf https://discovery.ucl.ac.uk/id/eprint/10190518/ |
| Rights: | open |
| Αριθμός Καταχώρησης: | edsbas.899A7DE7 |
| Βάση Δεδομένων: | BASE |
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