Dissertation/Thesis
Προβολή σε EDS

Exploring appropriate offset values for pencil beam and Monte Carlo dose optimization in lung stereotactic body radiotherapy encompassing the effects of respiration and tumor location

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Exploring appropriate offset values for pencil beam and Monte Carlo dose optimization in lung stereotactic body radiotherapy encompassing the effects of respiration and tumor location
Συνεισφορές: Evans, Grant (author), Shang, Charles (Thesis advisor), Florida Atlantic University (Degree grantor), Charles E. Schmidt College of Science, Department of Physics
Στοιχεία εκδότη: Florida Atlantic University
Συλλογή: FAU Digital Collections (Florida Atlantic University Digital Library)
Θεματικοί όροι: Drug development -- Computer simulation, Image guided radiation therapy, Lung cancer -- Treatment, Monte Carlo method, Proton beams, Transport theory
Περιγραφή: Evaluation of dose optimization using the Pencil Beam (PB) and Monte Carlo (MC) algorithms may allow physicists to apply dosimetric offsets to account for inaccuracies of the PB algorithm for lung cancer treatment with Stereotactic Body Radiotherapy (SBRT). 20 cases of Non-Small Cell Lung Cancer (NSCLC) were selected. Treatment plans were created with Brainlab iPlanDose® 4.1.2. The D97 of the Planning Target Volume (PTV) was normalized to 50 Gy on the Average Intensity Projection (AIP) using the fast PB and compared with MC. This exact plan with the same beam Monitor Units (MUs) was recalculated over each respiratory phase. The results show that the PB algorithm has a 2.3-2.4% less overestimation at the maximum exhalation phase than the maximum inhalation phase when compared to MC. Significantly smaller dose difference between PB and MC is also shown in plans for peripheral lesions (7.7 ± 0.7%) versus central lesions (12.7±0.8%)(p< 0.01). ; Includes bibliography. ; Thesis (M.S.)--Florida Atlantic University, 2014. ; FAU Electronic Theses and Dissertations Collection
Τύπος εγγράφου: Thesis
Περιγραφή αρχείου: 83 p.; application/pdf; Electronic Thesis or Dissertation
Γλώσσα: English
Relation: FA00004105; http://purl.flvc.org/fau/fd/FA00004105; https://fau.digital.flvc.org/islandora/object/fau%3A13442/datastream/TN/view/%20Exploring%20appropriate%20offset%20values%20for%20pencil%20beam%20and%20Monte%20Carlo%20dose%20optimization%20in%20lung%20stereotactic%20body%20radiotherapy%20encompassing%20the%20effects%20of%20respiration%20and%20tumor%20location.jpg
Διαθεσιμότητα: http://purl.flvc.org/fau/fd/FA00004105
https://fau.digital.flvc.org/islandora/object/fau%3A13442/datastream/TN/view/%20Exploring%20appropriate%20offset%20values%20for%20pencil%20beam%20and%20Monte%20Carlo%20dose%20optimization%20in%20lung%20stereotactic%20body%20radiotherapy%20encompassing%20the%20effects%20of%20respiration%20and%20tumor%20location.jpg
Rights: Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. ; http://rightsstatements.org/vocab/InC/1.0/
Αριθμός Καταχώρησης: edsbas.8917C01D
Βάση Δεδομένων: BASE
FullText Text:
  Availability: 0
CustomLinks:
  – Url: http://purl.flvc.org/fau/fd/FA00004105#
    Name: EDS - BASE (ns324271)
    Category: fullText
    Text: View record from BASE
Header DbId: edsbas
DbLabel: BASE
An: edsbas.8917C01D
RelevancyScore: 672
AccessLevel: 3
PubType: Dissertation/Thesis
PubTypeId: unknown
PreciseRelevancyScore: 671.999938964844
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Exploring appropriate offset values for pencil beam and Monte Carlo dose optimization in lung stereotactic body radiotherapy encompassing the effects of respiration and tumor location
– Name: Author
  Label: Contributors
  Group: Au
  Data: Evans, Grant (author)&lt;br /&gt;Shang, Charles (Thesis advisor)&lt;br /&gt;Florida Atlantic University (Degree grantor)&lt;br /&gt;Charles E. Schmidt College of Science&lt;br /&gt;Department of Physics
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: Florida Atlantic University
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: FAU Digital Collections (Florida Atlantic University Digital Library)
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Drug+development+--+Computer+simulation%22&quot;&gt;Drug development -- Computer simulation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Image+guided+radiation+therapy%22&quot;&gt;Image guided radiation therapy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Lung+cancer+--+Treatment%22&quot;&gt;Lung cancer -- Treatment&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Monte+Carlo+method%22&quot;&gt;Monte Carlo method&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Proton+beams%22&quot;&gt;Proton beams&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Transport+theory%22&quot;&gt;Transport theory&lt;/searchLink&gt;
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Evaluation of dose optimization using the Pencil Beam (PB) and Monte Carlo (MC) algorithms may allow physicists to apply dosimetric offsets to account for inaccuracies of the PB algorithm for lung cancer treatment with Stereotactic Body Radiotherapy (SBRT). 20 cases of Non-Small Cell Lung Cancer (NSCLC) were selected. Treatment plans were created with Brainlab iPlanDose&#174; 4.1.2. The D97 of the Planning Target Volume (PTV) was normalized to 50 Gy on the Average Intensity Projection (AIP) using the fast PB and compared with MC. This exact plan with the same beam Monitor Units (MUs) was recalculated over each respiratory phase. The results show that the PB algorithm has a 2.3-2.4% less overestimation at the maximum exhalation phase than the maximum inhalation phase when compared to MC. Significantly smaller dose difference between PB and MC is also shown in plans for peripheral lesions (7.7 &#177; 0.7%) versus central lesions (12.7&#177;0.8%)(p&lt; 0.01). ; Includes bibliography. ; Thesis (M.S.)--Florida Atlantic University, 2014. ; FAU Electronic Theses and Dissertations Collection
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: Thesis
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: 83 p.; application/pdf; Electronic Thesis or Dissertation
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: FA00004105; http://purl.flvc.org/fau/fd/FA00004105; https://fau.digital.flvc.org/islandora/object/fau%3A13442/datastream/TN/view/%20Exploring%20appropriate%20offset%20values%20for%20pencil%20beam%20and%20Monte%20Carlo%20dose%20optimization%20in%20lung%20stereotactic%20body%20radiotherapy%20encompassing%20the%20effects%20of%20respiration%20and%20tumor%20location.jpg
– Name: URL
  Label: Availability
  Group: URL
  Data: http://purl.flvc.org/fau/fd/FA00004105&lt;br /&gt;https://fau.digital.flvc.org/islandora/object/fau%3A13442/datastream/TN/view/%20Exploring%20appropriate%20offset%20values%20for%20pencil%20beam%20and%20Monte%20Carlo%20dose%20optimization%20in%20lung%20stereotactic%20body%20radiotherapy%20encompassing%20the%20effects%20of%20respiration%20and%20tumor%20location.jpg
– Name: Copyright
  Label: Rights
  Group: Cpyrght
  Data: Copyright &#169; is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. ; http://rightsstatements.org/vocab/InC/1.0/
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsbas.8917C01D
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.8917C01D
RecordInfo BibRecord:
  BibEntity:
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: Drug development -- Computer simulation
        Type: general
      – SubjectFull: Image guided radiation therapy
        Type: general
      – SubjectFull: Lung cancer -- Treatment
        Type: general
      – SubjectFull: Monte Carlo method
        Type: general
      – SubjectFull: Proton beams
        Type: general
      – SubjectFull: Transport theory
        Type: general
    Titles:
      – TitleFull: Exploring appropriate offset values for pencil beam and Monte Carlo dose optimization in lung stereotactic body radiotherapy encompassing the effects of respiration and tumor location
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Evans, Grant (author)
      – PersonEntity:
          Name:
            NameFull: Shang, Charles (Thesis advisor)
      – PersonEntity:
          Name:
            NameFull: Florida Atlantic University (Degree grantor)
      – PersonEntity:
          Name:
            NameFull: Charles E. Schmidt College of Science
      – PersonEntity:
          Name:
            NameFull: Department of Physics
    IsPartOfRelationships:
      – BibEntity:
          Identifiers:
            – Type: issn-locals
              Value: edsbas
            – Type: issn-locals
              Value: edsbas.oa
ResultId 1