Bibliographic Details
| Title: |
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c |
| Authors: |
Zhou, B., Sheffer, K.E., Bennett, J.E., Gregg, E.W., Danaei, G., Singleton, R.K., Shaw, J.E., Mishra, A., Lhoste, V.P.F., Carrillo-Larco, R.M., Kengne, A.P., Phelps, N.H., Heap, R.A., Rayner, A.W., Stevens, G.A., Paciorek, C.J., Riley, L.M., Cowan, M.J., Savin, S., Vander Hoorn, S., Lu, Y., Pavkov, M.E., Imperatore, G., Aguilar-Salinas, C.A., Ahmad, N.A., Anjana, R.M., Davletov, K., Farzadfar, F., González-Villalpando, C., Khang, Y.-H., Kim, H.C., Laatikainen, T., Laxmaiah, A., Mbanya, J.C.N., Narayan, K.M.V., Ramachandran, A., Wade, A.N., Zdrojewski, T., Abbasi-Kangevari, M., Rahim, H.F.A., Abu-Rmeileh, N.M., Adambekov, S., Adams, R.J., Aekplakorn, W., Agdeppa, I.A., Aghazadeh-Attari, J., Agyemang, C., Ahmadi, A., Ahmadi, N., Ahmed, S.H., Ajlouni, K., Al-Hinai, H., Al-Lahou, B., Al-Lawati, J.A., Asfoor, D.A., Al Qaoud, N.M., Alarouj, M., AlBuhairan, F., AlDhukair, S., Aldwairji, M.A., Ali, M.M., Alinezhad, F., Alkandari, A., Alomirah, H.F., Aly, E., Amarapurkar, D.N., Andersen, L.B., Anderssen, S.A., Andrade, D.S., Ansari-Moghaddam, A., Aounallah-Skhiri, H., Aris, T., Arlappa, N., Aryal, K.K., Assah, F.K., Assembekov, B., Auvinen, J., Avdi?ová, M., Azad, K., Azimi-Nezhad, M., Azizi, F., Bacopoulou, F., Balakrishna, N., Bamoshmoosh, M., Banach, M., Bandosz, P., Banegas, J.R., Barbagallo, C.M., Barceló, A., Bareti?, M., Barrera, L., Basit, A., Batieha, A.M., Batista, A.P., Baur, L.A., Belavendra, A., Ben Romdhane, H., Benet, M., Berkinbayev, S., Bernabe-Ortiz, A., Berrios Carrasola, X., Bettiol, H., Beybey, A.F., Bhargava, S.K., Bika Lele, E.C., Bikbov, M.M., Bista, B., Bjerregaard, P., Bjertness, E., Bjertness, M.B., Björkelund, C., Bloch, K.V., Blokstra, A., Bo, S., Bobak, M., Boggia, J.G., Bonaccio, M., Bonilla-Vargas, A., Borghs, H., Bovet, P., Brajkovich, I., Brenner, H., Brewster, L.M., Brian, G.R., Briceño, Y., Brito, M., Bugge, A., Buntinx, F., Cabrera de León, A., Caixeta, R.B., Can, G., Cândido, A.P.C., Capanzana, M.V., apková, N., Capuano, E., Capuano, R., Capuano, V., Cardoso, V.C., Carlsson, A.C., Casanueva Freijo, Felipe, Censi, L., Cervantes-Loaiza, M., Chamnan, P., Chamukuttan, S., Chan, Q., Charchar, F.J., Chaturvedi, N., Chen, H., Cheraghian, B., Chirlaque, M.-D., Chudek, J., Cifkova, R., Cirillo, M., Claessens, F., Cohen, E., Concin, H., Cooper, C., Costanzo, S., Cowell, C., Crujeiras Martínez, Ana Belén, Cruz, J.J., Cureau, F.V., Cuschieri, S., D'Arrigo, G., d'Orsi, E., Dallongeville, J., Damasceno, A., Dastgiri, S., De Curtis, A., de Gaetano, G., De Henauw, S., Deepa, M., DeGennaro, V., Demarest, S., Dennison, E., Deschamps, V., Dhimal, M., Dika, Z., Djalalinia, S., Donfrancesco, C., Dong, G., Dorobantu, M., Dörr, M., Dragano, N., Drygas, W., Du, Y., Duante, C.A., Duboz, P., Dushpanova, A., Dziankowska-Zaborszczyk, E., Ebrahimi, N., Eddie, R., Eftekhar, E., Efthymiou, V., Egbagbe, E.E., Eghtesad, S., El-Khateeb, M., El Ati, J., Eldemire-Shearer, D., Elosua, R., Enang, O., Erasmus, R.T., Erbel, R., Erem, C., Ergor, G., Eriksen, L., Eriksson, J.G., Esmaeili, A., Evans, R.G., Fakhradiyev, I., Fall, C.H., Faramarzi, E., Farjam, M., Farzi, Y., Fattahi, M.R., Fawwad, A., Felix-Redondo, F.J., Ferguson, T.S., Fernández-Bergés, D., Ferrari, M., Ferreccio, C., Ferreira, H.S., Ferrer, E., Feskens, E.J.M., Flood, D., Forsner, M., Fosse, S., Fottrell, E.F., Fouad, H.M., Francis, D.K., Frontera, G., Furusawa, T., Gaciong, Z., Garnett, S.P., Gasull, M., Gazzinelli, A., Gehring, U., Ghaderi, E., Ghamari, S.-H., Ghanbari, A., Ghasemi, E., Gheorghe-Fronea, O.-F., Ghimire, A., Gialluisi, A., Giampaoli, S., Gianfagna, F., Gill, T.K., Gironella, G., Giwercman, A., Goltzman, D., Gomula, A., Gonçalves, H., Gonçalves, M., Gonzalez-Chica, D.A., Gonzalez-Gross, M., González-Rivas, J.P., González-Villalpando, M.-E., Gonzalez, A.R., Gottrand, F., Grafnetter, D., Grodzicki, T., Grøntved, A., Guerrero, R., Gujral, U.P., Gupta, R., Gutierrez, L., Gwee, X., Haghshenas, R., Hakimi, H., Hambleton, I.R., Hamzeh, B., Hanekom, W.A., Hange, D., Hantunen, S., Hao, J., Hari Kumar, R., Harooni, J., Hashemi-Shahri, S.M., Hata, J., Heidemann, C., Henrique, R.S., Herrala, S., Herzig, K.-H., Heshmat, R., Ho, S.Y., Holdsworth, M., Homayounfar, R., Hopman, W.M., Horimoto, A.R.V.R., Hormiga, C., Horta, B.L., Houti, L., Howitt, C., Htay, T.T., Htet, A.S., Htike, M.M.T., Huerta, J.M., Huhtaniemi, I.T., Huisman, M., Husseini, A., Huybrechts, I., Iacoviello, L., Iakupova, E.M., Iannone, A.G., Ibrahim Wong, N., Ijoma, C., Irazola, V.E., Ishida, T., Isiguzo, G.C., Islam, S.M.S., Islek, D., Ittermann, T., Iwasaki, M., Jääskeläinen, T., Jacobs, J.M., Jaddou, H.Y., Jadoul, M., Jallow, B., James, K., Jamil, K.M., Janus, E., Jarvelin, M.-R., Jasienska, G., Jelakovi?, A., Jelakovi?, B., Jennings, G., Jha, A.K., Jimenez, R.O., Jöckel, K.-H., Jokelainen, J.J., Jonas, J.B., Joshi, P., Josipovi?, J., Joukar, F., Jó?wiak, J., Kafatos, A., Kajantie, E.O., Kalmatayeva, Z., Karki, K.B., Katibeh, M., Kauhanen, J., Kazakbaeva, G.M., Kaze, F.F., Ke, C., Keinänen-Kiukaanniemi, S., Kelishadi, R., Keramati, M., Kersting, M., Khader, Y.S., Khaledifar, A., Khalili, D., Kheiri, B., Kheradmand, M., Khosravi, A., Kiechl-Kohlendorfer, U., Kiechl, S.J., Kiechl, S., Kingston, A., Klakk, H., Klanova, J., Knoflach, M., Kolsteren, P., König, J., Korpelainen, R., Korrovits, P., Kos, J., Koskinen, S., Kowlessur, S., Koziel, S., Kriemler, S., Kristensen, P.L., Kromhout, D., Kubinova, R., Kujala, U.M., Kulimbet, M., Kurjata, P., Kyobutungi, C., La, Q.N., Labadarios, D., Lachat, C., Laid, Y., Lall, L., Lankila, T., Lanska, V., Lappas, G., Larijani, B., Latt, T.S., Laurenzi, M., Lehmann, N., Lehtimäki, T., Lemogoum, D., Leung, G.M., Li, Y., Lima-Costa, M.F., Lin, H.-H., Lind, L., Lissner, L., Liu, X., Lopez-Garcia, E., Lopez, T., Lozano, J.E., Luksiene, D., Lundqvist, A., Lunet, N., Lustigová, M., Machado-Coelho, G.L.L., Machado-Rodrigues, A.M., Macia, E., Macieira, L.M., Madar, A.A., Maestre, G.E., Maggi, S., Magliano, D.J., Magriplis, E., Mahasampath, G., Maire, B., Makdisse, M., Malekpour, M.-R., Malekzadeh, F., Malekzadeh, R., Mallikharjuna Rao, K., Malyutina, S., Maniego, L.V., Manios, Y., Mannix, M.I., Mansour-Ghanaei, F., Manzato, E., Margozzini, P., Mariño, J., Marques, L.P., Martorell, R., Mascarenhas, L.P., Masinaei, M., Mathiesen, E.B., Matsha, T.E., Mc Donald Posso, A.J., McFarlane, S.R., McGarvey, S.T., Mediene Benchekor, S., Mehlig, K., Mehrparvar, A.H., Melgarejo, J.D., Méndez, F., Menezes, A.M.B., Mereke, A., Meshram, I.I., Meto, D.T., Minderico, C.S., Mini, G.K., Miquel, J.F., Miranda, J.J., Mirjalili, M.R., Modesti, P.A., Moghaddam, S.S., Mohamed, M.K., Mohammad, K., Mohammadi, M.R., Mohammadi, Z., Mohammadifard, N., Mohammadpourhodki, R., Mohan, V., Mohd Yusoff, M.F., Mohebbi, I., Møller, N.C., Molnár, D., Momenan, A., Mondo, C.K., Montenegro Mendoza, R.A., Monterrubio-Flores, E., Moosazadeh, M., Moradpour, F., Morejon, A., Moreno, L.A., Morgan, K., Morin, S.N., Moslem, A., Mosquera, M., Mossakowska, M., Mostafa, A., Mostafavi, S.-A., Motlagh, M.E., Motta, J., Msyamboza, K.P., Mu, T.T., Muiesan, M.L., Mursu, J., Musa, K.I., Mustafa, N., Muyer, M.T.M.C., Nabipour, I., Nagel, G., Naidu, B.M., Najafi, F., Náme?ná, J., Nangia, V.B., Naseri, T., Neelapaichit, N., Nejatizadeh, A., Nenko, I., Nervi, F., Ng, T.P., Nguyen, C.T., Nguyen, Q.N., Ni, M.Y., Nie, P., Nieto-Martínez, R.E., Ninomiya, T., Noale, M., Noboa, O.A., Noto, D., Nsour, M.A., Nuho?lu, I., O'Neill, T.W., Odili, A.N., Oh, K., Ohtsuka, R., Omar, M.A., Onat, A., Ong, S.K., Onodugo, O., Ordunez, P., Ornelas, R., Ortiz, P.J., Osmond, C., Ostovar, A., Otero, J.A., Ottendahl, C.B., Otu, A., Owusu-Dabo, E., Palmieri, L., Pan, W.-H., Panda-Jonas, S., Panza, F., Paoli, M., Park, S., Parsaeian, M., Patel, N.D., Pechlaner, R., Pe?in, I., Pedro, J.M., Peixoto, S.V., Peltonen, M., Pereira, A.C., Pessôa dos Prazeres, T.M., Peykari, N., Phall, M.C., Pham, S.T., Phan, H.H., Pichardo, R.N., Pikhart, H., Pilav, A., Piler, P., Pitakaka, F., Piwonska, A., Pizarro, A.N., Plans-Rubió, P., Plata, S., Porta, M., Poudyal, A., Pourfarzi, F., Pourshams, A., Poustchi, H., Pradeepa, R., Providencia, R., Puder, J.J., Puhakka, S., Punab, M., Qorbani, M., Quintana, H.K., Quoc Bao, T., Rahimikazerooni, S., Raitakari, O., Ramirez-Zea, M., Ramke, J., Ramos, R., Rampal, L., Rampal, S., Rangel Reina, D.A., Rashidi, M.-M., Redon, J., Renner, J.D.P., Reuter, C.P., Revilla, L., Rezaei, N., Rezaianzadeh, A., Rigo, F., Roa, R.G., Robinson, L., Rodríguez-Artalejo, F., Rodriguez-Perez, M.C., Rodríguez-Villamizar, L.A., Rodríguez, A.Y., Roggenbuck, U., Rohloff, P., Romeo, E.L., Rosengren, A., Rubinstein, A., Rust, P., Rutkowski, M., Sabbaghi, H., Sachdev, H.S., Sadjadi, A., Safarpour, A.R., Safi, S., Safiri, S., Saghi, M.H., Saidi, O., Saki, N., alaj, S., Salanave, B., Salonen, J.T., Salvetti, M., Sánchez-Abanto, J., Santos, D.A., Santos, L.C., Santos, M.P., Santos, T.R., Saramies, J.L., Sardinha, L.B., Sarrafzadegan, N., Saum, K.-U., Sbaraini, M., Scazufca, M., Schaan, B.D., Scheidt-Nave, C., Schipf, S., Schmidt, C.O., Schöttker, B., Schramm, S., Sebert, S., Sedaghattalab, M., Sein, A.A., Sepanlou, S.G., Sewpaul, R., Shamah-Levy, T., Shamshirgaran, S.M., Sharafkhah, M., Sharma, S.K., Sharman, A., Shayanrad, A., Shayesteh, A.A., Shimizu-Furusawa, H., Shiri, R., Shrestha, N., Si-Ramlee, K., Silva, D.A.S., Simon, M., Simons, J., Simons, L.A., Sjöström, M., Slowikowska-Hilczer, J., Slusarczyk, P., Smeeth, L., Sobngwi, E., Söderberg, S., Soemantri, A., Sofat, R., Solfrizzi, V., Somi, M.H., Soumaré, A., Sousa-Poza, A., Sparrenberger, K., Staessen, J.A., Stavreski, B., Steene-Johannessen, J., Stehle, P., Stein, A.D., Stessman, J., Stokwiszewski, J., Stronks, K., Suarez-Ortegón, M.F., Suebsamran, P., Sundström, J., Suriyawongpaisal, P., Sylva, R.C., Szklo, M., Tamosiunas, A., Tarawneh, M.R., Tarqui-Mamani, C.B., Taylor, A., Taylor, J., Tello, T., Thankappan, K.R., Theobald, H., Theodoridis, X., Thomas, N., Thrift, A.G., Timmermans, E.J., Tjandrarini, D.H., Tolonen, H.K., Tolstrup, J.S., Tomaszewski, M., Topbas, M., Torres-Collado, L., Traissac, P., Triantafyllou, A., Tuitele, J., Tuliakova, A.M., Tulloch-Reid, M.K., Tuomainen, T.-P., Tzala, E., Tzourio, C., Ueda, P., Ugel, E., Ukoli, F.A.M., Ulmer, H., Uusitalo, H.M.T., Valdivia, G., van den Born, B.-J., Van der Heyden, J., Van Minh, H., van Rossem, L., Van Schoor, N.M., van Valkengoed, I.G.M., van Zutphen, E.M., Vanderschueren, D., Vanuzzo, D., Vasan, S.K., Vega, T., Velasquez-Melendez, G., Verstraeten, R., Viet, L., Villalpando, S., Vioque, J., Virtanen, J.K., Viswanathan, B., Voutilainen, A., Wan Bebakar, W.M., Wan Mohamud, W.N., Wang, C., Wang, N., Wang, Q., Wang, Y.X., Wang, Y.-W., Wannamethee, S.G., Webster-Kerr, K., Wedderkopp, N., Wei, W., Westbury, L.D., Whincup, P.H., Widhalm, K., Widyahening, I.S., Wi?cek, A., Wilks, R.J., Willeit, J., Willeit, P., Wilsgaard, T., Wojtyniak, B., Wong, A., Wong, E.B., Woodward, M., Wu, F.C., Xu, H., Xu, L., Yaacob, N.A., Yan, L., Yan, W., Yoosefi, M., Yoshihara, A., Younger-Coleman, N.O., Yu, Y.-L., Yu, Y., Yusoff, A.F., Zainuddin, A.A., Zamani, F., Zambon, S., Zampelas, A., Zaw, K.K., Zeljkovic Vrkic, T., Zeng, Y., Zhang, Z.-Y., Zholdin, B., Zimmet, P., Zitt, E., Zoghlami, N., Zuñiga Cisneros, J., Ezzati, M. |
| Publication Year: |
2023 |
| Subject Terms: |
Humans, Glycated Hemoglobin, Glucose, Blood Glucose, Prevalence, Diabetes Mellitus, Fasting, AS Santiago, IDIS |
| Description: |
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance. ; This study was funded by the UK Medical Research Council (grant number MR/V034057/1 to M.E.), the UK Research and Innovation (Research England Policy Support Fund to M.E.) and the US Centers for Disease Control and Prevention (to E.W.G.). B. Zhou is supported by a fellowship from the Abdul Latif Jameel Institute for Disease and Emergency Analytics, funded by a donation from Community Jameel, at Imperial College London. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. For the purpose of open access, the author has applied a Creative Commons Attribution license to the Author Accepted ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
This study was funded by the UK Medical Research Council (grant number MR/V034057/1 to M.E.), the UK Research and Innovation (Research England Policy Support Fund to M.E.) and the US Centers for Disease Control and Prevention (to E.W.G.). B. Zhou is suppor [MR/V034057/1]; UK Medical Research Council; UK Research and Innovation (Research England Policy Support Fund); US Centers for Disease Control and Prevention; Abdul Latif Jameel Institute for Disease and Emergency Analytics; MRC [MR/V034057/1, MC_UU_12011/3] Funding Source: UKRI; British Heart Foundation [RG/19/4/34452, RG/13/16/30528] Funding Source: researchfish; Medical Research Council [MC_UU_12011/1, U1475000002, MC_UP_A620_1016, MC_UP_A620_1014, MC_UU_12011/2, U1475000001, MC_U147585819, MC_UU_12011/3, G0400491, MC_U147585824, MC_UP_A620_1015, MC_U147585827, G0601019, U1475000003] Funding Source: researchfish; National Institute for Health Research [NF-SI-0513-10085, NF-SI-0508-10082, 10/33/04] Funding Source: researchfish; Versus Arthritis [19583] Funding Source: researchfish; Grants-in-Aid for Scientific Research [20H00045] Funding Source: KAKEN; https://doi.org/10.1038/s41591-023-02610-2; https://portalcientifico.sergas.gal//documentos/656c717529159508cf237fd2; https://hdl.handle.net/20.500.11940/21608; 656c717529159508cf237fd2 |
| DOI: |
10.1038/s41591-023-02610-2 |
| Availability: |
https://hdl.handle.net/20.500.11940/21608
https://portalcientifico.sergas.gal//documentos/656c717529159508cf237fd2
https://doi.org/10.1038/s41591-023-02610-2 |
| Rights: |
Attribution 4.0 International (CC BY 4.0) ; http://creativecommons.org/licenses/by/4.0/ ; openAccess |
| Accession Number: |
edsbas.6341E046 |
| Database: |
BASE |