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Draft Genome Sequence and Virulence Factors of Fusobacterium vincentii KCOM 2880 Isolated from Human Subgingival Plaque

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Title: Draft Genome Sequence and Virulence Factors of Fusobacterium vincentii KCOM 2880 Isolated from Human Subgingival Plaque
Authors: Park, SN, Lim, YK, Ji, S, Kook, JK
Contributors: 110562, Ji, S
Publication Year: 2025
Subject Terms: Fusobacterium vincentii, genome, periodontitis, virulence factors
Description: Fusobacterium vincentii, recently reclassified from subspecies to species status, is an oral anaerobe associated with periodontal disease. We report the draft genome sequence of strain KCOM 2880, isolated from human subgingival plaque. The genome (2,054,883 bp, three contigs) encodes 1,969 genes, including 1,848 protein-coding sequences, 56 pseudogenes, 65 RNA genes, and one CRISPR array. Virulence factor analysis identified 77 genes, including four FadA adhesins, five cell surface proteins, seven autotransporters, serine proteases, a type II secretion system, and TonB-dependent and hemin receptors. These results may provide genomic insights into the pathogenic potential of F. vincentii.
Document Type: article in journal/newspaper
Language: English
Relation: J01598642X; http://repository.ajou.ac.kr/handle/201003/34841
DOI: 10.48022/mbl.2510.10003
Availability: http://repository.ajou.ac.kr/handle/201003/34841
https://doi.org/10.48022/mbl.2510.10003
Accession Number: edsbas.60767439
Database: BASE
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  – Url: http://repository.ajou.ac.kr/handle/201003/34841#
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  Label: Title
  Group: Ti
  Data: Draft Genome Sequence and Virulence Factors of Fusobacterium vincentii KCOM 2880 Isolated from Human Subgingival Plaque
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Park%2C+SN%22">Park, SN</searchLink><br /><searchLink fieldCode="AR" term="%22Lim%2C+YK%22">Lim, YK</searchLink><br /><searchLink fieldCode="AR" term="%22Ji%2C+S%22">Ji, S</searchLink><br /><searchLink fieldCode="AR" term="%22Kook%2C+JK%22">Kook, JK</searchLink>
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  Data: 110562<br />Ji, S
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  Data: 2025
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  Data: <searchLink fieldCode="DE" term="%22Fusobacterium+vincentii%22">Fusobacterium vincentii</searchLink><br /><searchLink fieldCode="DE" term="%22genome%22">genome</searchLink><br /><searchLink fieldCode="DE" term="%22periodontitis%22">periodontitis</searchLink><br /><searchLink fieldCode="DE" term="%22virulence+factors%22">virulence factors</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Fusobacterium vincentii, recently reclassified from subspecies to species status, is an oral anaerobe associated with periodontal disease. We report the draft genome sequence of strain KCOM 2880, isolated from human subgingival plaque. The genome (2,054,883 bp, three contigs) encodes 1,969 genes, including 1,848 protein-coding sequences, 56 pseudogenes, 65 RNA genes, and one CRISPR array. Virulence factor analysis identified 77 genes, including four FadA adhesins, five cell surface proteins, seven autotransporters, serine proteases, a type II secretion system, and TonB-dependent and hemin receptors. These results may provide genomic insights into the pathogenic potential of F. vincentii.
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  Data: J01598642X; http://repository.ajou.ac.kr/handle/201003/34841
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  Data: 10.48022/mbl.2510.10003
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  Data: http://repository.ajou.ac.kr/handle/201003/34841<br />https://doi.org/10.48022/mbl.2510.10003
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      – SubjectFull: Fusobacterium vincentii
        Type: general
      – SubjectFull: genome
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      – SubjectFull: periodontitis
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      – TitleFull: Draft Genome Sequence and Virulence Factors of Fusobacterium vincentii KCOM 2880 Isolated from Human Subgingival Plaque
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