Academic Journal
Προβολή σε EDS

Imaging the eye as a window to brain health: frontier approaches and future directions

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Imaging the eye as a window to brain health: frontier approaches and future directions
Συγγραφείς: Banna, Hasan U., Slayo, Mary, Armitage, James A., del Rosal, Blanca, Vocale, Loretta, Spencer, Sarah J.
Πηγή: http://lobid.org/resources/99370676031606441#!, 21(1):309.
Έτος έκδοσης: 2024
Συλλογή: Publisso (ZB MED-Publikationsportal Lebenswissenschaften)
Θεματικοί όροι: Brain/pathology [MeSH], Brain/diagnostic imaging [MeSH], Brain Diseases/diagnosis [MeSH], Humans [MeSH], Optical Imaging/trends [MeSH], Review, Brain Diseases/pathology [MeSH], Brain Diseases/diagnostic imaging [MeSH], Retina/diagnostic imaging [MeSH], Animals [MeSH], Retina/pathology [MeSH], Optical Imaging/methods [MeSH]
Περιγραφή: Recent years have seen significant advances in diagnostic testing of central nervous system (CNS) function and disease. However, there remain challenges in developing a comprehensive suite of non- or minimally invasive assays of neural health and disease progression. Due to the direct connection with the CNS, structural changes in the neural retina, retinal vasculature and morphological changes in retinal immune cells can occur in parallel with disease conditions in the brain. The retina can also, uniquely, be assessed directly and non-invasively. For these reasons, the retina may prove to be an important 'window' for revealing and understanding brain disease. In this review, we discuss the gross anatomy of the eye, focusing on the sensory and non-sensory cells of the retina, especially microglia, that lend themselves to diagnosing brain disease by imaging the retina. We include a history of ocular imaging to describe the different imaging approaches undertaken in the past and outline current and emerging technologies including retinal autofluorescence imaging, Raman spectroscopy, and artificial intelligence image analysis. These new technologies show promising potential for retinal imaging to be used as a tool for the diagnosis of brain disorders such as Alzheimer's disease and others and the assessment of treatment success.
Τύπος εγγράφου: article in journal/newspaper
Γλώσσα: English
Relation: https://repository.publisso.de/resource/frl:6500954; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606158/
DOI: 10.1186/s12974-024-03304-3
Διαθεσιμότητα: https://repository.publisso.de/resource/frl:6500954
https://doi.org/10.1186/s12974-024-03304-3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606158/
Rights: https://creativecommons.org/licenses/by-nc-nd/4.0/
Αριθμός Καταχώρησης: edsbas.5563D97
Βάση Δεδομένων: BASE
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://repository.publisso.de/resource/frl:6500954#
    Name: EDS - BASE (ns324271)
    Category: fullText
    Text: View record from BASE
Header DbId: edsbas
DbLabel: BASE
An: edsbas.5563D97
RelevancyScore: 945
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 944.983581542969
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Imaging the eye as a window to brain health: frontier approaches and future directions
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Banna%2C+Hasan+U%2E%22">Banna, Hasan U.</searchLink><br /><searchLink fieldCode="AR" term="%22Slayo%2C+Mary%22">Slayo, Mary</searchLink><br /><searchLink fieldCode="AR" term="%22Armitage%2C+James+A%2E%22">Armitage, James A.</searchLink><br /><searchLink fieldCode="AR" term="%22del+Rosal%2C+Blanca%22">del Rosal, Blanca</searchLink><br /><searchLink fieldCode="AR" term="%22Vocale%2C+Loretta%22">Vocale, Loretta</searchLink><br /><searchLink fieldCode="AR" term="%22Spencer%2C+Sarah+J%2E%22">Spencer, Sarah J.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <i>http://lobid.org/resources/99370676031606441#!, 21(1):309</i>.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2024
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: Publisso (ZB MED-Publikationsportal Lebenswissenschaften)
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Brain%2Fpathology+[MeSH]%22">Brain/pathology [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Brain%2Fdiagnostic+imaging+[MeSH]%22">Brain/diagnostic imaging [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+Diseases%2Fdiagnosis+[MeSH]%22">Brain Diseases/diagnosis [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Humans+[MeSH]%22">Humans [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Optical+Imaging%2Ftrends+[MeSH]%22">Optical Imaging/trends [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Review%22">Review</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+Diseases%2Fpathology+[MeSH]%22">Brain Diseases/pathology [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+Diseases%2Fdiagnostic+imaging+[MeSH]%22">Brain Diseases/diagnostic imaging [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Retina%2Fdiagnostic+imaging+[MeSH]%22">Retina/diagnostic imaging [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Animals+[MeSH]%22">Animals [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Retina%2Fpathology+[MeSH]%22">Retina/pathology [MeSH]</searchLink><br /><searchLink fieldCode="DE" term="%22Optical+Imaging%2Fmethods+[MeSH]%22">Optical Imaging/methods [MeSH]</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Recent years have seen significant advances in diagnostic testing of central nervous system (CNS) function and disease. However, there remain challenges in developing a comprehensive suite of non- or minimally invasive assays of neural health and disease progression. Due to the direct connection with the CNS, structural changes in the neural retina, retinal vasculature and morphological changes in retinal immune cells can occur in parallel with disease conditions in the brain. The retina can also, uniquely, be assessed directly and non-invasively. For these reasons, the retina may prove to be an important 'window' for revealing and understanding brain disease. In this review, we discuss the gross anatomy of the eye, focusing on the sensory and non-sensory cells of the retina, especially microglia, that lend themselves to diagnosing brain disease by imaging the retina. We include a history of ocular imaging to describe the different imaging approaches undertaken in the past and outline current and emerging technologies including retinal autofluorescence imaging, Raman spectroscopy, and artificial intelligence image analysis. These new technologies show promising potential for retinal imaging to be used as a tool for the diagnosis of brain disorders such as Alzheimer's disease and others and the assessment of treatment success.
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article in journal/newspaper
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: https://repository.publisso.de/resource/frl:6500954; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606158/
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1186/s12974-024-03304-3
– Name: URL
  Label: Availability
  Group: URL
  Data: https://repository.publisso.de/resource/frl:6500954<br />https://doi.org/10.1186/s12974-024-03304-3<br />https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606158/
– Name: Copyright
  Label: Rights
  Group: Cpyrght
  Data: https://creativecommons.org/licenses/by-nc-nd/4.0/
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsbas.5563D97
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.5563D97
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s12974-024-03304-3
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: Brain/pathology [MeSH]
        Type: general
      – SubjectFull: Brain/diagnostic imaging [MeSH]
        Type: general
      – SubjectFull: Brain Diseases/diagnosis [MeSH]
        Type: general
      – SubjectFull: Humans [MeSH]
        Type: general
      – SubjectFull: Optical Imaging/trends [MeSH]
        Type: general
      – SubjectFull: Review
        Type: general
      – SubjectFull: Brain Diseases/pathology [MeSH]
        Type: general
      – SubjectFull: Brain Diseases/diagnostic imaging [MeSH]
        Type: general
      – SubjectFull: Retina/diagnostic imaging [MeSH]
        Type: general
      – SubjectFull: Animals [MeSH]
        Type: general
      – SubjectFull: Retina/pathology [MeSH]
        Type: general
      – SubjectFull: Optical Imaging/methods [MeSH]
        Type: general
    Titles:
      – TitleFull: Imaging the eye as a window to brain health: frontier approaches and future directions
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Banna, Hasan U.
      – PersonEntity:
          Name:
            NameFull: Slayo, Mary
      – PersonEntity:
          Name:
            NameFull: Armitage, James A.
      – PersonEntity:
          Name:
            NameFull: del Rosal, Blanca
      – PersonEntity:
          Name:
            NameFull: Vocale, Loretta
      – PersonEntity:
          Name:
            NameFull: Spencer, Sarah J.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-locals
              Value: edsbas
            – Type: issn-locals
              Value: edsbas.oa
          Titles:
            – TitleFull: http://lobid.org/resources/99370676031606441#!, 21(1):309
              Type: main
ResultId 1