Dissertation/ Thesis
Προβολή σε EDS

Methods for detecting structural similarities: characterisation of conserved motifs within structural families for genome annotation ; Méthodes de détection des similarités structurales : caractérisation des motifs conservés dans les familles de structures pour l’annotation des génomes

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Methods for detecting structural similarities: characterisation of conserved motifs within structural families for genome annotation ; Méthodes de détection des similarités structurales : caractérisation des motifs conservés dans les familles de structures pour l’annotation des génomes
Συγγραφείς: Carpentier, Mathilde
Συνεισφορές: Institut de Systématique, Evolution, Biodiversité (ISYEB), Muséum national d'Histoire naturelle (MNHN)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA), Atelier de BioInformatique (ABI), Sorbonne Université (SU), Université Pierre et Marie Curie (Paris VI), Dr Joël Pothier, Pr Pierre Netter
Πηγή: https://hal.sorbonne-universite.fr/tel-05711041 ; Bio-informatique [q-bio.QM]. Université Pierre et Marie Curie (Paris VI), 2005. Français. ⟨NNT : 2005PA066571⟩.
Στοιχεία εκδότη: CCSD
Έτος έκδοσης: 2005
Συλλογή: Université des Antilles (UAG): HAL
Θεματικοί όροι: Protein structure, structural alignment, multiple structural alignment, search for structural common patterns, protein structural classification, Structure des protéines, alignement structural, alignement structural multiple, recherche de motifs structuraux communs, classification des structures protéiques, familles structurales des protéines, protein structural families, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics, Phylogenetics and taxonomy
Περιγραφή: The identification of the structural similarities in proteins brings multiple information in connection with the relations between the sequences, the structures and the functions of proteins. A protein structural database scanning method and program has been developed that made possible to establish a procedure of classification of protein structures in families. The structural blocks preserved among the structures in the same family can be defined. Three methods of multiple structure comparison working at the local level were developped, each one answering different criteria. They were used to determine local structural blocks common to proteins of the same family. These common structural blocks will constitute a relevant base of cores intended to be integrated in a fold recognition method (threading). This method of prediction of the protein structures only from their sequences can be used at ends of annotation of unknown sequences, the identified similarities being undetectable by the methods using only sequence information. The analysis of these structural blocks will bring also many information about the conservation (and evolution) of the structures. ; L'identification des similarités structurales dans les protéines apporte de multiples informations à propos des relations entre les séquences, les structures et les fonctions. Une méthode de recherche de similarités structurales locales dans une banque de structures a été développée. Elle a permis d'établir une procédure de classification des structures en familles. Les blocs structuraux conservés parmi les structures de même famille peuvent ensuite être définis. Trois méthodes de comparaison multiple et locales de structures ont été mises en place, chacune répondant à des critères différents. Elles ont été utilisées pour déterminer des blocs structuraux locaux communs aux protéines d'une même famille. Ces blocs structuraux communs constitueront une base pertinente de \og c\oe urs\fg~destinée à être intégrée dans un logiciel de reconnaissance de repliement ...
Τύπος εγγράφου: doctoral or postdoctoral thesis
Γλώσσα: French
Relation: NNT: 2005PA066571
Διαθεσιμότητα: https://hal.sorbonne-universite.fr/tel-05711041
https://hal.sorbonne-universite.fr/tel-05711041v2/document
https://hal.sorbonne-universite.fr/tel-05711041v2/file/These.pdf
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/ ; info:eu-repo/semantics/OpenAccess
Αριθμός Καταχώρησης: edsbas.3AB18C5
Βάση Δεδομένων: BASE
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://hal.sorbonne-universite.fr/tel-05711041#
    Name: EDS - BASE (ns324271)
    Category: fullText
    Text: View record from BASE
Header DbId: edsbas
DbLabel: BASE
An: edsbas.3AB18C5
RelevancyScore: 757
AccessLevel: 3
PubType: Dissertation/ Thesis
PubTypeId: dissertation
PreciseRelevancyScore: 756.674377441406
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Methods for detecting structural similarities: characterisation of conserved motifs within structural families for genome annotation ; Méthodes de détection des similarités structurales : caractérisation des motifs conservés dans les familles de structures pour l’annotation des génomes
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Carpentier%2C+Mathilde%22">Carpentier, Mathilde</searchLink>
– Name: Author
  Label: Contributors
  Group: Au
  Data: Institut de Systématique, Evolution, Biodiversité (ISYEB)<br />Muséum national d'Histoire naturelle (MNHN)-École Pratique des Hautes Études (EPHE)<br />Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)<br />Atelier de BioInformatique (ABI)<br />Sorbonne Université (SU)<br />Université Pierre et Marie Curie (Paris VI)<br />Dr Joël Pothier<br />Pr Pierre Netter
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <i>https://hal.sorbonne-universite.fr/tel-05711041 ; Bio-informatique [q-bio.QM]. Université Pierre et Marie Curie (Paris VI), 2005. Français. ⟨NNT : 2005PA066571⟩</i>.
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: CCSD
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2005
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: Université des Antilles (UAG): HAL
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Protein+structure%22">Protein structure</searchLink><br /><searchLink fieldCode="DE" term="%22structural+alignment%22">structural alignment</searchLink><br /><searchLink fieldCode="DE" term="%22multiple+structural+alignment%22">multiple structural alignment</searchLink><br /><searchLink fieldCode="DE" term="%22search+for+structural+common+patterns%22">search for structural common patterns</searchLink><br /><searchLink fieldCode="DE" term="%22protein+structural+classification%22">protein structural classification</searchLink><br /><searchLink fieldCode="DE" term="%22Structure+des+protéines%22">Structure des protéines</searchLink><br /><searchLink fieldCode="DE" term="%22alignement+structural%22">alignement structural</searchLink><br /><searchLink fieldCode="DE" term="%22alignement+structural+multiple%22">alignement structural multiple</searchLink><br /><searchLink fieldCode="DE" term="%22recherche+de+motifs+structuraux+communs%22">recherche de motifs structuraux communs</searchLink><br /><searchLink fieldCode="DE" term="%22classification+des+structures+protéiques%22">classification des structures protéiques</searchLink><br /><searchLink fieldCode="DE" term="%22familles+structurales+des+protéines%22">familles structurales des protéines</searchLink><br /><searchLink fieldCode="DE" term="%22protein+structural+families%22">protein structural families</searchLink><br /><searchLink fieldCode="DE" term="%22[INFO%2EINFO-BI]Computer+Science+[cs]%2FBioinformatics+[q-bio%2EQM]%22">[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EBBM%2EBS]Life+Sciences+[q-bio]%2FBiochemistry%22">[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+Biology%2FStructural+Biology+[q-bio%2EBM]%22">Molecular Biology/Structural Biology [q-bio.BM]</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EBBM%2EGTP]Life+Sciences+[q-bio]%2FBiochemistry%22">[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+Biology%2FGenomics+[q-bio%2EGN]%22">Molecular Biology/Genomics [q-bio.GN]</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EBIBS]Life+Sciences+[q-bio]%2FQuantitative+Methods+[q-bio%2EQM]%22">[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EBID%2EEVO]Life+Sciences+[q-bio]%2FBiodiversity%2FPopulations+and+Evolution+[q-bio%2EPE]%22">[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EBID%2ESPT]Life+Sciences+[q-bio]%2FBiodiversity%2FSystematics%22">[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics</searchLink><br /><searchLink fieldCode="DE" term="%22Phylogenetics+and+taxonomy%22">Phylogenetics and taxonomy</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: The identification of the structural similarities in proteins brings multiple information in connection with the relations between the sequences, the structures and the functions of proteins. A protein structural database scanning method and program has been developed that made possible to establish a procedure of classification of protein structures in families. The structural blocks preserved among the structures in the same family can be defined. Three methods of multiple structure comparison working at the local level were developped, each one answering different criteria. They were used to determine local structural blocks common to proteins of the same family. These common structural blocks will constitute a relevant base of cores intended to be integrated in a fold recognition method (threading). This method of prediction of the protein structures only from their sequences can be used at ends of annotation of unknown sequences, the identified similarities being undetectable by the methods using only sequence information. The analysis of these structural blocks will bring also many information about the conservation (and evolution) of the structures. ; L'identification des similarités structurales dans les protéines apporte de multiples informations à propos des relations entre les séquences, les structures et les fonctions. Une méthode de recherche de similarités structurales locales dans une banque de structures a été développée. Elle a permis d'établir une procédure de classification des structures en familles. Les blocs structuraux conservés parmi les structures de même famille peuvent ensuite être définis. Trois méthodes de comparaison multiple et locales de structures ont été mises en place, chacune répondant à des critères différents. Elles ont été utilisées pour déterminer des blocs structuraux locaux communs aux protéines d'une même famille. Ces blocs structuraux communs constitueront une base pertinente de \og c\oe urs\fg~destinée à être intégrée dans un logiciel de reconnaissance de repliement ...
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: doctoral or postdoctoral thesis
– Name: Language
  Label: Language
  Group: Lang
  Data: French
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: NNT: 2005PA066571
– Name: URL
  Label: Availability
  Group: URL
  Data: https://hal.sorbonne-universite.fr/tel-05711041<br />https://hal.sorbonne-universite.fr/tel-05711041v2/document<br />https://hal.sorbonne-universite.fr/tel-05711041v2/file/These.pdf
– Name: Copyright
  Label: Rights
  Group: Cpyrght
  Data: https://creativecommons.org/licenses/by-nc-sa/4.0/ ; info:eu-repo/semantics/OpenAccess
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsbas.3AB18C5
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.3AB18C5
RecordInfo BibRecord:
  BibEntity:
    Languages:
      – Text: French
    Subjects:
      – SubjectFull: Protein structure
        Type: general
      – SubjectFull: structural alignment
        Type: general
      – SubjectFull: multiple structural alignment
        Type: general
      – SubjectFull: search for structural common patterns
        Type: general
      – SubjectFull: protein structural classification
        Type: general
      – SubjectFull: Structure des protéines
        Type: general
      – SubjectFull: alignement structural
        Type: general
      – SubjectFull: alignement structural multiple
        Type: general
      – SubjectFull: recherche de motifs structuraux communs
        Type: general
      – SubjectFull: classification des structures protéiques
        Type: general
      – SubjectFull: familles structurales des protéines
        Type: general
      – SubjectFull: protein structural families
        Type: general
      – SubjectFull: [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]
        Type: general
      – SubjectFull: [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry
        Type: general
      – SubjectFull: Molecular Biology/Structural Biology [q-bio.BM]
        Type: general
      – SubjectFull: [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry
        Type: general
      – SubjectFull: Molecular Biology/Genomics [q-bio.GN]
        Type: general
      – SubjectFull: [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
        Type: general
      – SubjectFull: [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
        Type: general
      – SubjectFull: [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics
        Type: general
      – SubjectFull: Phylogenetics and taxonomy
        Type: general
    Titles:
      – TitleFull: Methods for detecting structural similarities: characterisation of conserved motifs within structural families for genome annotation ; Méthodes de détection des similarités structurales : caractérisation des motifs conservés dans les familles de structures pour l’annotation des génomes
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Carpentier, Mathilde
      – PersonEntity:
          Name:
            NameFull: Institut de Systématique, Evolution, Biodiversité (ISYEB)
      – PersonEntity:
          Name:
            NameFull: Muséum national d'Histoire naturelle (MNHN)-École Pratique des Hautes Études (EPHE)
      – PersonEntity:
          Name:
            NameFull: Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)
      – PersonEntity:
          Name:
            NameFull: Atelier de BioInformatique (ABI)
      – PersonEntity:
          Name:
            NameFull: Sorbonne Université (SU)
      – PersonEntity:
          Name:
            NameFull: Université Pierre et Marie Curie (Paris VI)
      – PersonEntity:
          Name:
            NameFull: Dr Joël Pothier
      – PersonEntity:
          Name:
            NameFull: Pr Pierre Netter
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2005
          Identifiers:
            – Type: issn-locals
              Value: edsbas
            – Type: issn-locals
              Value: edsbas.oa
          Titles:
            – TitleFull: https://hal.sorbonne-universite.fr/tel-05711041 ; Bio-informatique [q-bio.QM]. Université Pierre et Marie Curie (Paris VI), 2005. Français. ⟨NNT : 2005PA066571⟩
              Type: main
ResultId 1