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A Perspective on the Added Value of Red Blood Cells during Cardiac Hypothermic Oxygenated Perfusion
| Τίτλος: | A Perspective on the Added Value of Red Blood Cells during Cardiac Hypothermic Oxygenated Perfusion |
|---|---|
| Συγγραφείς: | Vervoorn, Mats T, Ballan, Elisa M, Kaffka Genaamd Dengler, Selma E, Meijborg, Veronique M F, de Jager, Saskia C A, Van Wijk, Richard, van der Kaaij, Niels P, Arts Assistenten CTC, Innovatie CTC, Experimentele Afd. Cardiologie 2, Circulatory Health, Infection & Immunity, CDL Cluster Speciële Diagnostiek, Child Health, Regenerative Medicine and Stem Cells, CTC |
| Έτος έκδοσης: | 2025 |
| Θεματικοί όροι: | cardiac HOPE, donor heart preservation, ex-situ heart perfusion, heart transplantation, red blood cells, Taverne, Cardiology and Cardiovascular Medicine, Transplantation, Pulmonary and Respiratory Medicine, Surgery |
| Περιγραφή: | Hypothermic oxygenated perfusion (HOPE) is an emerging technique for donor heart preservation that is currently being studied in multiple clinical trials with promising results. When compared to HOPE for other organs, cardiac protocols involve red blood cell (RBC) supplementation, despite absence of comparative evidence for its benefits. In this perspective paper, we discuss the pros and cons of the addition of RBCs during cardiac HOPE. Although the current clinical results with RBC supplementation during HOPE seem promising, potential downsides of RBC supplementation cannot be ruled out. The impact of supplemented RBCs during cardiac HOPE requires further investigation to improve HOPE protocols, to optimize heart preservation using this promising technology. |
| Τύπος εγγράφου: | other non-article part of journal/newspaper |
| Περιγραφή αρχείου: | text/plain |
| Γλώσσα: | English |
| ISSN: | 1053-2498 |
| Relation: | https://dspace.library.uu.nl/handle/1874/458349 |
| Διαθεσιμότητα: | https://dspace.library.uu.nl/handle/1874/458349 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| Αριθμός Καταχώρησης: | edsbas.2BEB0804 |
| Βάση Δεδομένων: | BASE |
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