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Intraductal fully covered self-expanding metal stents in the management of post-liver transplant anastomotic strictures: a UK wide experience

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Τίτλος: Intraductal fully covered self-expanding metal stents in the management of post-liver transplant anastomotic strictures: a UK wide experience
Συγγραφείς: Ahmed, W, Kyle, D, Khanna, A, Devlin, J, Reffitt, D, Zeino, Z, Webster, G, Phillpotts, S, Gordon, R, Corbett, G, Gelson, W, Nayar, M, Khan, H, Cramp, M, Potts, J, Fateen, W, Miller, H, Paranandi, B, Huggett, M, Everett, SM, Hegade, VS, O’Kane, R, Scott, R, McDougall, N, Harrison, P, Joshi, D
Στοιχεία εκδότη: SAGE Publications
England
Έτος έκδοσης: 2022
Συλλογή: PEARL (Plymouth Electronic Archiv & ResearchLibrary, Plymouth University)
Θεματικοί όροι: biliary stricture, ERCP, intra-ductal fully covered metal stent, liver transplant
Περιγραφή: Background: Fully covered intraductal self-expanding metal stents (IDSEMS) have been well described in the management of post-liver transplant (LT) anastomotic strictures (ASs). Their antimigration waists and intraductal nature make them suited for deployment across the biliary anastomosis. Objectives: We conducted a multicentre study to analyse their use and efficacy in the management of AS. Design: This was a retrospective, multicentre observational study across nine tertiary centres in the United Kingdom. Methods: Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with IDSEMS insertion were analysed retrospectively. Recorded variables included patient demographics, procedural characteristics, response to therapy and follow-up data. Results: In all, 162 patients (100 males, 62%) underwent 176 episodes of IDSEMS insertion for AS. Aetiology of liver disease in this cohort included hepatocellular carcinoma ( n = 35, 22%), followed by alcohol-related liver disease ( n = 29, 18%), non-alcoholic steatohepatitis ( n = 20, 12%), primary biliary cholangitis ( n = 15, 9%), acute liver failure ( n = 13, 8%), viral hepatitis ( n = 13, 8%) and autoimmune hepatitis ( n = 12, 7%). Early AS occurred in 25 (15%) cases, delayed in 32 (20%) cases and late in 95 (59%) cases. Age at transplant was 54 years (range, 12–74), and stent duration was 15 weeks (range, 3 days–78 weeks). In total, 131 (81%) had complete resolution of stricture at endoscopic re-evaluation. Stricture recurrence was observed in 13 (10%) cases, with a median of 19 weeks ...
Τύπος εγγράφου: article in journal/newspaper
Περιγραφή αρχείου: 175628482211224-175628482211224; Electronic-eCollection; application/pdf
Γλώσσα: English
ISSN: 1756-283X
1756-2848
Relation: E-ISSN:1756-2848; http://hdl.handle.net/10026.1/19816
DOI: 10.1177/17562848221122473
Διαθεσιμότητα: http://hdl.handle.net/10026.1/19816
https://doi.org/10.1177/17562848221122473
Αριθμός Καταχώρησης: edsbas.28F12239
Βάση Δεδομένων: BASE
Περιγραφή
ISSN:1756283X
17562848
DOI:10.1177/17562848221122473