Academic Journal
Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries
| Τίτλος: | Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries |
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| Συγγραφείς: | Li, C, Bishop, TRP, Imamura, F, Sharp, SJ, Pearce, M, Brage, S, Ong, KK, Ahsan, H, Bes-Rastrollo, M, Beulens, JWJ, den Braver, N, Byberg, L, Canhada, S, Chen, Z, Chung, H-F, Cortés-Valencia, A, Djousse, L, Drouin-Chartier, J-P, Du, H, Du, S, Duncan, BB, Gaziano, JM, Gordon-Larsen, P, Goto, A, Haghighatdoost, F, Härkänen, T, Hashemian, M, Hu, FB, Ittermann, T, Järvinen, R, Kakkoura, MG, Neelakantan, N, Knekt, P, Lajous, M, Li, Y, Magliano, DJ, Malekzadeh, R, Le Marchand, L, Marques-Vidal, P, Martinez-Gonzalez, MA, Maskarinec, G, Mishra, GD, Mohammadifard, N, O'Donoghue, G, O'Gorman, D, Popkin, B, Poustchi, H, Sarrafzadegan, N, Sawada, N, Schmidt, MI, Shaw, JE, Soedamah-Muthu, S, Stern, D, Tong, L, van Dam, RM, Völzke, H, Willett, WC, Wolk, A, Yu, C, Consortium, EPIC-InterAct, Forouhi, NG, Wareham, NJ |
| Στοιχεία εκδότη: | Elsevier |
| Έτος έκδοσης: | 2025 |
| Συλλογή: | Oxford University Research Archive (ORA) |
| Περιγραφή: | Background Meat consumption could increase the risk of type 2 diabetes. However, evidence is largely based on studies of European and North American populations, with heterogeneous analysis strategies and a greater focus on red meat than on poultry. We aimed to investigate the associations of unprocessed red meat, processed meat, and poultry consumption with type 2 diabetes using data from worldwide cohorts and harmonised analytical approaches. Methods This individual-participant federated meta-analysis involved data from 31 cohorts participating in the InterConnect project. Cohorts were from the region of the Americas (n=12) and the Eastern Mediterranean (n=2), European (n=9), South-East Asia (n=1), and Western Pacific (n=7) regions. Access to individual-participant data was provided by each cohort; participants were eligible for inclusion if they were aged 18 years or older and had available data on dietary consumption and incident type 2 diabetes and were excluded if they had a diagnosis of any type of diabetes at baseline or missing data. Cohort-specific hazard ratios (HRs) and 95% CIs were estimated for each meat type, adjusted for potential confounders (including BMI), and pooled using a random-effects meta-analysis, with meta-regression to investigate potential sources of heterogeneity. Findings Among 1 966 444 adults eligible for participation, 107 271 incident cases of type 2 diabetes were identified during a median follow-up of 10 (IQR 7–15) years. Median meat consumption across cohorts was 0–110 g/day for unprocessed red meat, 0–49 g/day for processed meat, and 0–72 g/day for poultry. Greater consumption of each of the three types of meat was associated with increased incidence of type 2 diabetes, with HRs of 1·10 (95% CI 1·06–1·15) per 100 g/day of unprocessed red meat (I2=61%), 1·15 (1·11–1·20) per 50 g/day of processed meat (I2=59%), and 1·08 (1·02–1·14) per 100 g/day of poultry (I2=68%). Positive associations between meat consumption and type 2 diabetes were observed in North America and in the ... |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| DOI: | 10.1016/s2213-8587(24)00179-7 |
| Διαθεσιμότητα: | https://doi.org/10.1016/s2213-8587(24)00179-7 https://ora.ox.ac.uk/objects/uuid:f140ed4d-9bce-4591-9a2f-5973f6b9a85f |
| Rights: | info:eu-repo/semantics/openAccess |
| Αριθμός Καταχώρησης: | edsbas.1ACE3CD5 |
| Βάση Δεδομένων: | BASE |
| DOI: | 10.1016/s2213-8587(24)00179-7 |
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