Report
Biological Foundations of Universal Sexual Transition
| Title: | Biological Foundations of Universal Sexual Transition |
|---|---|
| Authors: | Blatt, Kate Lynn |
| Contributors: | Blatt, Kate Lynn |
| Publisher Information: | Zenodo |
| Publication Year: | 2025 |
| Collection: | Zenodo |
| Subject Terms: | Longevity, Longevity/genetics, Longevity/physiology, Longevity/ethics, Longevity/immunology, Longevity/drug effects, Longevity/radiation effects |
| Description: | The prevailing framework describes “menopause” in women and “andropause” in men as sex-specific declines in reproductive hormones that mark the end of fertility. This framing emphasizes deficit and loss. In this paper, I propose a corrective reinterpretation: menopause and its male analogues are not failures of the body but part of a universal, late-life sexual transition. Across sexes, aging brings systematic changes in hormone levels, secondary sex characteristics, psychological profiles, and social roles. These changes are not pathological but developmental. Late life is a transition from procreative sexual dimorphism to a convergent phenotype blending traits of both sexes. I trace the history of the menopause concept, present biological and sociological evidence for sex convergence with age, and compare these natural processes with gender-affirming hormone therapies to highlight mechanistic parallels. I then define metrics—the Transition Index (TI) and Sex-Characteristic Convergence Score (SCC)—to quantify transition trajectories. Candidate datasets and statistical models are described to make the hypothesis falsifiable. The implications are wide-ranging: new biomarkers for longevity research, new approaches to clinical care, challenges to rigid gender binaries, and recognition of elders as stabilizers in social systems. The central claim is radical but testable: there is no menopause or andropause. There is only universal sexual transition. |
| Document Type: | report |
| Language: | English |
| Relation: | https://zenodo.org/records/17203222; oai:zenodo.org:17203222; https://doi.org/10.5281/zenodo.17203222 |
| DOI: | 10.5281/zenodo.17203222 |
| Availability: | https://doi.org/10.5281/zenodo.17203222 https://zenodo.org/records/17203222 |
| Rights: | Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode ; Kate Lynn Blatt |
| Accession Number: | edsbas.10BA68FF |
| Database: | BASE |
| FullText | Text: Availability: 0 CustomLinks: – Url: https://doi.org/10.5281/zenodo.17203222# Name: EDS - BASE (ns324271) Category: fullText Text: View record from BASE |
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| Items | – Name: Title Label: Title Group: Ti Data: Biological Foundations of Universal Sexual Transition – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Blatt%2C+Kate+Lynn%22">Blatt, Kate Lynn</searchLink> – Name: Author Label: Contributors Group: Au Data: Blatt, Kate Lynn – Name: Publisher Label: Publisher Information Group: PubInfo Data: Zenodo – Name: DatePubCY Label: Publication Year Group: Date Data: 2025 – Name: Subset Label: Collection Group: HoldingsInfo Data: Zenodo – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Longevity%22">Longevity</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fgenetics%22">Longevity/genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fphysiology%22">Longevity/physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fethics%22">Longevity/ethics</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fimmunology%22">Longevity/immunology</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fdrug+effects%22">Longevity/drug effects</searchLink><br /><searchLink fieldCode="DE" term="%22Longevity%2Fradiation+effects%22">Longevity/radiation effects</searchLink> – Name: Abstract Label: Description Group: Ab Data: The prevailing framework describes “menopause” in women and “andropause” in men as sex-specific declines in reproductive hormones that mark the end of fertility. This framing emphasizes deficit and loss. In this paper, I propose a corrective reinterpretation: menopause and its male analogues are not failures of the body but part of a universal, late-life sexual transition. Across sexes, aging brings systematic changes in hormone levels, secondary sex characteristics, psychological profiles, and social roles. These changes are not pathological but developmental. Late life is a transition from procreative sexual dimorphism to a convergent phenotype blending traits of both sexes. I trace the history of the menopause concept, present biological and sociological evidence for sex convergence with age, and compare these natural processes with gender-affirming hormone therapies to highlight mechanistic parallels. I then define metrics—the Transition Index (TI) and Sex-Characteristic Convergence Score (SCC)—to quantify transition trajectories. Candidate datasets and statistical models are described to make the hypothesis falsifiable. The implications are wide-ranging: new biomarkers for longevity research, new approaches to clinical care, challenges to rigid gender binaries, and recognition of elders as stabilizers in social systems. The central claim is radical but testable: there is no menopause or andropause. There is only universal sexual transition. – Name: TypeDocument Label: Document Type Group: TypDoc Data: report – Name: Language Label: Language Group: Lang Data: English – Name: NoteTitleSource Label: Relation Group: SrcInfo Data: https://zenodo.org/records/17203222; oai:zenodo.org:17203222; https://doi.org/10.5281/zenodo.17203222 – Name: DOI Label: DOI Group: ID Data: 10.5281/zenodo.17203222 – Name: URL Label: Availability Group: URL Data: https://doi.org/10.5281/zenodo.17203222<br />https://zenodo.org/records/17203222 – Name: Copyright Label: Rights Group: Cpyrght Data: Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode ; Kate Lynn Blatt – Name: AN Label: Accession Number Group: ID Data: edsbas.10BA68FF |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.5281/zenodo.17203222 Languages: – Text: English Subjects: – SubjectFull: Longevity Type: general – SubjectFull: Longevity/genetics Type: general – SubjectFull: Longevity/physiology Type: general – SubjectFull: Longevity/ethics Type: general – SubjectFull: Longevity/immunology Type: general – SubjectFull: Longevity/drug effects Type: general – SubjectFull: Longevity/radiation effects Type: general Titles: – TitleFull: Biological Foundations of Universal Sexual Transition Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Blatt, Kate Lynn – PersonEntity: Name: NameFull: Blatt, Kate Lynn IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2025 Identifiers: – Type: issn-locals Value: edsbas – Type: issn-locals Value: edsbas.oa |
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