Academic Journal

First Clade Ib Monkeypox Virus Infection Reported in the Americas — California, November 2024

Bibliographic Details
Title: First Clade Ib Monkeypox Virus Infection Reported in the Americas — California, November 2024
Authors: Levy, Vivian, Branzuela, Anna, Hsieh, Kristina, Getabecha, Shiffen, Berumen, Ricardo, Saadeh, Kayla, Snyder, Robert E., Marek, Gillian, Dodson, Daniel, Newman, Alyssa, Hacker, Jill K., Kath, Chantha, Minhaj, Faisal S., Gigante, Crystal M., Gearhart, Shannon, Kallen, Alexander, Hutson, Christina L., Jacobson, Kathleen, Avina, Robert, Bunao, Josh, Cayabyab, Jahara, Chojolan, Edwin, Epson, Erin, Espinosa, Alex, Gonzaga, Bianca, Haw, Monica, Johnson, Kelly A., Keinde, Awa, Lemoine, Deidra, Maccuish, Kelsey, McGonagle, Alexia, Ng, Rilene, Piper, Rachel, Probert, Will, Salas, Maria, Stavig, Brandon, Stoltey, Juliet, Tafolla, Orlanda, Tang, Eric C., Wadford, Debra A., Watson, Jessica, Wong, Vivian, Belay, Ermias, Cash-Goldwasser, Shama, Davidson, Whitni, Deng, Jiusheng, De Perio, Marie, Gertz, Alida, Hunter, David W., Kofman, Aaron, Lash, Ryan, McCollum, Andrea M., McNaghten, A.D., Rao, Agam K., Satheshkumar, Panayampalli S., Sims, Emily, Williams, Ian, Zecca, Italo
Source: MMWR Morb Mortal Wkly Rep
Publisher Information: Centers for Disease Control MMWR Office, 2025.
Publication Year: 2025
Subject Terms: Mpox, Monkeypox, Male, Adult, Travel, Humans, Full Report, Monkeypox virus, Middle Aged, Americas, Travel-Related Illness, California, Disease Outbreaks
Description: A clade I monkeypox virus (MPXV) outbreak is ongoing in the Democratic Republic of the Congo; travel-associated clade I MPXV infections have been reported in non-African countries. In November 2024, San Mateo County Health in California identified an electronic laboratory report of polymerase chain reaction results suggestive of clade I MPXV infection in a male traveler who had recently returned from East Africa. After conferring with the California Department of Public Health (CDPH), a county health department worker visited the patient that same day at his home and obtained skin pustule swab specimens for expedited clade I MPXV testing. Clade I MPXV was confirmed the following day by the CDPH Viral and Rickettsial Disease Laboratory. This was the first reported clade I MPXV infection in the Americas. Among 83 identified contacts, five received JYNNEOS vaccine as postexposure prophylaxis. All contacts were monitored for 21 days; no secondary cases were identified. Patients with mpox-compatible lesions or clinical features should receive MPXV testing, and health care providers should immediately notify public health authorities of suspected clade I MPXV infections (e.g., mpox manifestations and travel history to an area with ongoing clade I MPXV transmission) or upon receiving a nonvariola orthopoxvirus DNA detected, clade II MPXV DNA undetectable test result to trigger additional testing and facilitate the rapid implementation of transmission-based precautions and other preventive public health interventions.
Document Type: Article
Other literature type
ISSN: 1545-861X
0149-2195
DOI: 10.15585/mmwr.mm7404a1
Access URL: https://pubmed.ncbi.nlm.nih.gov/39946302
Rights: URL: http://creativecommons.org/publicdomain/zero/1.0/All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.
Accession Number: edsair.doi.dedup.....de5d4c9b16aef0cb48c7b0b9c86705ab
Database: OpenAIRE
Description
ISSN:1545861X
01492195
DOI:10.15585/mmwr.mm7404a1