Academic Journal
Multiple Severe Intracranial Stenoses with Ischemic Stroke in Neuroborreliosis-associated Cerebral Vasculitis: Endovascular Treatment Strategies and Literature Review
| Title: | Multiple Severe Intracranial Stenoses with Ischemic Stroke in Neuroborreliosis-associated Cerebral Vasculitis: Endovascular Treatment Strategies and Literature Review |
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| Authors: | Kamran Hajiyev, Michael Forsting, Alexandru Cimpoca, Ali Khanafer, Hansjörg Bäzner, Hans Henkes |
| Source: | Clin Neuroradiol |
| Publisher Information: | Springer Science and Business Media LLC, 2024. |
| Publication Year: | 2024 |
| Subject Terms: | Male, Adult, Endovascular Procedures, Medizin, Middle Aged, Cerebral Angiography, Anti-Bacterial Agents, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Humans, Lyme Neuroborreliosis, Original Article, Female, Female [MeSH], Ischemic Stroke/surgery [MeSH], Vasculitis, Central Nervous System/diagnostic imaging [MeSH], Anti-Bacterial Agents/therapeutic use [MeSH], Endovascular Procedures/methods [MeSH], Adult [MeSH], Lyme Neuroborreliosis/complications [MeSH], Humans [MeSH], Treatment Outcome [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Intracranial stenting, Vessel wall imaging, Male [MeSH], Cerebral Angiography/methods [MeSH], Ischemic Stroke/diagnostic imaging [MeSH], Cerebral vasculitis, Ischemic Stroke/etiology [MeSH], Vasculitis, Central Nervous System/complications [MeSH], Endovascular treatment, Child [MeSH], Ischemic stroke, Lyme neuroborreliosis, Vasculitis, Central Nervous System, Child, Ischemic Stroke, Retrospective Studies |
| Description: | Introduction Neuroborreliosis is the disseminated form of Lyme borreliosis and refers to the involvement of the central nervous system by Borrelia burgdorferi sensu lato spirochetes. Several reports suggest its emergence as a potential cause of cerebral vasculitis and stroke in children and young adults. The objective of this paper is to highlight endovascular treatment options within this context. Methods The medicinal and endovascular treatments of three patients—two adults and one child—with ischemic stroke resulting from neuroborreliosis-associated severe cerebral vasculitis were retrospectively assessed. Detailed descriptions of the clinical course, treatments, and follow-up data for each patient are provided. Additionally, a literature review focusing on endovascular treatment options within this topic was conducted. Results Both endovascular and medicinal treatments resulted in excellent clinical outcomes in all three patients, with no observed periprocedural complications. Significant clinical improvement was noted during mid-term follow-up. Follow-up angiographies confirmed stent patency. Conclusion Endovascular interventions as a bailout strategy may enhance clinical outcomes in patients with vascular complications of neuroborreliosis, especially when medicinal therapy alone fails to achieve further improvement. In the setting of severe ischemic stroke with sub-occlusive large vessel stenosis or occlusion, the cause of which is often unknown, it should be considered to prioritize prompt endovascular treatment, even if neuroborreliosis is suspected on admission. |
| Document Type: | Article Other literature type |
| Language: | English |
| ISSN: | 1869-1447 1869-1439 |
| DOI: | 10.1007/s00062-024-01447-7 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/39134673 https://repository.publisso.de/resource/frl:6505198 https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85201324452 https://doi.org/10.1007/s00062-024-01447-7 https://www.ncbi.nlm.nih.gov/pubmed/39134673 |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....9c2ac153b2b4f49562dca1a7c7fa4c31 |
| Database: | OpenAIRE |
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