Academic Journal

EFFECT OF BRONCHODILATORS ON HEART RATE VARIABILITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Bibliographic Details
Title: EFFECT OF BRONCHODILATORS ON HEART RATE VARIABILITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: Array H. Shugushev, Array M. Vasilenko, Array V. Gurizeva
Source: Рациональная фармакотерапия в кардиологии, Vol 3, Iss 4, Pp 51-54 (2015)
Publisher Information: Silicea - Poligraf, 2007.
Publication Year: 2007
Subject Terms: 03 medical and health sciences, 0302 clinical medicine, аритмия, RC666-701, broncholytic therapy, бронхолитическая терапия, Diseases of the circulatory (Cardiovascular) system, Therapeutics. Pharmacology, RM1-950, хроническая обструктивная болезнь легких, arrhythmia, chronic obstructive pulmonary disease, 3. Good health
Description: Aim. To study effect of long-acting theophylline (Theotard, KRKA) and combination of salmeterol and fluticasone (Seretide, GlaxoSmithKline) on heart rhythm variability (HRV) and number of arrhythmic episodes in patients with chronic obstructive pulmonary disease (COPD).Material and methods. 144 patients with COPD and 35 patients of control group were examined. The analysis of HRV and Holter monitoring were made f on 2th and 14th days.Results. Treatment with both drugs led to increase in power of low- and high frequencies and their ratio (LF/HF), decrease in rate of supraventricular and ventricular arrhythmias. Theophylline therapy raised in a number of single and pair supraventricular extrasystoles. Treatment with combination of salmeterol and fluticasone did not change a number of extrasystoles.Conclusion. Combination of salmeterol and fluticasone is more preferable as a broncholytic therapy for patients with COPD and heart rhythm disorders.
Document Type: Article
ISSN: 2225-3653
1819-6446
DOI: 10.20996/1819-6446-2007-3-4-51-54
DOI: 10.1234/1819-6446-2007-4-51-54
Access URL: http://www.rpcardio.com/jour/article/download/505/526
https://doaj.org/article/b46f3c0cd3814ddaa6bb264898afc735
https://doaj.org/article/039a943eefe644c3b248f076ebdeff8c
https://www.rpcardio.com/jour/article/view/505
https://www.rpcardio.com/jour/article/download/505/526
Rights: CC BY
Accession Number: edsair.doi.dedup.....8a1c4748b105784bbb022ec57d59e4d0
Database: OpenAIRE
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