Academic Journal

Exploring the Latent Structure of Behavior Using the Human Connectome Project’s Data

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Exploring the Latent Structure of Behavior Using the Human Connectome Project’s Data
Συγγραφείς: Mikkel Schöttner, Thomas Bolton, Jagruti Patel, Anjali Tarun Nahálka, Sandra Viera, Patric Hagmann
Πηγή: Sci Rep
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Scientific reports, vol. 13, no. 1, pp. 713
Στοιχεία εκδότη: Center for Open Science, 2022.
Έτος έκδοσης: 2022
Θεματικοί όροι: 0301 basic medicine, Science, Brain, Magnetic Resonance Imaging, Article, 3. Good health, 03 medical and health sciences, Cognition, Mental Health, 0302 clinical medicine, Connectome, Medicine, Humans, Cluster Analysis, Connectome/methods, Brain/diagnostic imaging, Brain/physiology, Magnetic Resonance Imaging/methods
Περιγραφή: How behavior arises from brain physiology has been one central topic of investigation in neuroscience. Considering the recent interest in predicting behavior from brain imaging using open datasets, there is the need for a principled approach to the categorization of behavioral variables. However, this is not trivial, as the definitions of psychological constructs and their relationships—their ontology—are not always clear. Here, we propose to use exploratory factor analysis (EFA) as a data-driven approach to find robust and interpretable domains of behavior in the Human Connectome Project (HCP) dataset. Additionally, we explore the clustering of behavioral variables using consensus clustering.We find that four and five factors offer the best description of the data, a result corroborated by the consensus clustering. In the four-factor solution, factors for Mental Health, Cognition, Processing Speed, and Substance Use arise. With five factors, Mental Health splits into Well-Being and Internalizing. Clustering results show a similar pattern, with clusters for Cognition, Processing Speed, Positive Affect, Negative Affect, and Substance Use. The factor structure is replicated in an independent dataset using confirmatory factor analysis (CFA). We discuss how the content of the factors fits with previous conceptualizations of general behavioral domains.
Τύπος εγγράφου: Article
Conference object
Other literature type
Περιγραφή αρχείου: application/pdf
ISSN: 2045-2322
DOI: 10.31234/osf.io/3h987
DOI: 10.1038/s41598-022-27101-1
Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/36639406
https://doaj.org/article/e7615da06b594ae2a394b656619ed972
https://serval.unil.ch/notice/serval:BIB_1E1541AD189D
https://serval.unil.ch/resource/serval:BIB_1E1541AD189D.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1E1541AD189D8
Rights: CC BY
Αριθμός Καταχώρησης: edsair.doi.dedup.....88ae2af7f0d5d30cec0b99ae581e87eb
Βάση Δεδομένων: OpenAIRE
Περιγραφή
ISSN:20452322
DOI:10.31234/osf.io/3h987