Academic Journal
Electrophysiologic Characteristics of Complex Fractionated Atrial Electrograms in Patients with Atrial Fibrillation
| Title: | Electrophysiologic Characteristics of Complex Fractionated Atrial Electrograms in Patients with Atrial Fibrillation |
|---|---|
| Authors: | Hui Nam Pak, Sook Kyoung Kim, Jae Hyung Park, Hong Euy Lim, Jong I. Choi, Jin K. Jang, Younghoon Kim, Chun Hwang |
| Contributors: | JAE H. PARK, HUI-NAM PAK, SOOK K. KIM, JIN K. JANG, JONG I. CHOI, HONG E. LIM, CHUN HWANG, YOUNG-HOON KIM, Pak, Hui Nam |
| Source: | Journal of Cardiovascular Electrophysiology. 20:266-272 |
| Publisher Information: | Wiley, 2009. |
| Publication Year: | 2009 |
| Subject Terms: | Male, Heart Atria/physiopathology, complex fractionated atrial electrogram, conduction, Heart Conduction System/surgery, Body Surface Potential Mapping, Atrial Fibrillation/surgery, Middle Aged, Body Surface Potential Mapping/methods, Atrial Fibrillation/physiopathology, 03 medical and health sciences, 0302 clinical medicine, Heart Conduction System/physiopathology, Heart Conduction System, voltage, Atrial Fibrillation, Atrial Fibrillation/diagnosis, Humans, atrial fibrillation, Female, Heart Atria/surgery, Heart Atria |
| Description: | Mechanisms of CFAE. Introduction: The underlying mechanisms of complex fractionated atrial electrogram (CFAE) during radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) have not yet been clearly elucidated. We explored the relationships between CFAE and left atrial (LA) voltage, or conduction velocity (CV). Methods and Results: In 50 patients with AF (23 paroxysmal AF [PAF], 41 males, mean age 55.76 ± 10.16 years), the CFAE (average index of fractionation of electrograms during AF by interval‐analysis algorithm, cycle length [CL]≤ 120 ms) areas, voltage, and CV were measured at eight different quadrants in each patient's LA by analyzing a NavX‐guided, color‐coded CFAE CL map, a voltage map, and an isochronal map (500 ms pacing) generated by contact bipolar electrograms (70–100 points in the LA). The results were: (1) CFAE areas were predominantly located in the septum, roof, and LA appendage; (2) CFAE area had lower voltage than those in non‐CFAE area and was surrounded by the areas of high voltage (P < 0.0001); (3) The CFAE areas had low CVs compared with non‐CFAE areas (P < 0.001); and (4) The percentage of CFAE area was lower in patients with persistent atrial fibrillation (PeAF) compared with those with PAF (P < 0.05). Conclusions: The CFAE area, which is primarily located at the septum, has a low voltage with a lower CV, and is surrounded by high‐voltage areas. Underlying electroanatomical complexity is associated with clustering of CFAEs. (J Cardiovasc Electrophysiol, Vol. 20, pp. 266‐272, March 2009) |
| Document Type: | Article |
| File Description: | 266~272 |
| Language: | English |
| ISSN: | 1540-8167 1045-3873 |
| DOI: | 10.1111/j.1540-8167.2008.01321.x |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/19175848 https://pubmed.ncbi.nlm.nih.gov/19175848/ https://onlinelibrary.wiley.com/doi/10.1111/j.1540-8167.2008.01321.x https://www.ncbi.nlm.nih.gov/pubmed/19175848 https://europepmc.org/article/MED/19175848 https://yonsei.pure.elsevier.com/en/publications/electrophysiologic-characteristics-of-complex-fractionated-atrial https://koreauniv.pure.elsevier.com/en/publications/electrophysiologic-characteristics-of-complex-fractionated-atrial |
| Rights: | Wiley Online Library User Agreement CC BY NC ND |
| Accession Number: | edsair.doi.dedup.....6ad4a2930a7a7b7318b7dddfda2e40f5 |
| Database: | OpenAIRE |
| ISSN: | 15408167 10453873 |
|---|---|
| DOI: | 10.1111/j.1540-8167.2008.01321.x |