Academic Journal

Anisotropy of Longitudinal Relaxation in White Matter: Comparison of T1 and Magnetization Transfer

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Anisotropy of Longitudinal Relaxation in White Matter: Comparison of T1 and Magnetization Transfer
Συγγραφείς: Niklas Wallstein, André Pampel, Carsten Jäger, Roland Müller, Jens Stieler, Sven Martin, Markus Morawski, Harald Möller
Πηγή: ISMRM Annual Meeting.
Στοιχεία εκδότη: ISMRM, 2024.
Έτος έκδοσης: 2024
Περιγραφή: Motivation: Studies on the orientation dependence of T1 have led to contradictory observations, indicating that this effect is not well understood. Goal(s): Our primary objective was to meticulously explore the orientation dependency of T₁ under precisely controlled and stable conditions. Approach: Comprehensive T1 (inversion recovery) and magnetization-transfer (MT) experiments were performed in fixed spinal-cord samples, with systematic variation of the fiber-to-field angle θFB . Results: No relevant T1 variation with θFB was observed in the IR experiments. However, a clear orientation dependence was consistently observed in all MT experiments,Impact: Precise quantitative MR measurements in spinal cord with varying fiber-to-field angle showed no consistent orientation dependence of T1 but a clear effect for the MT saturation, indicating the MT effects may be responsible for the previously observed T1 anisotropy.
Τύπος εγγράφου: Article
ISSN: 1545-4428
DOI: 10.58530/2024/1311
Αριθμός Καταχώρησης: edsair.doi...........fbabe969c84af3f0cffe3cdee2967d5f
Βάση Δεδομένων: OpenAIRE
Περιγραφή
ISSN:15454428
DOI:10.58530/2024/1311