Academic Journal
Assessing the Stability of Routine Wastewater Parameters and Chemical Biomarkers as Population-Normalization Proxies in Wastewater-Based Epidemiology.
| Title: | Assessing the Stability of Routine Wastewater Parameters and Chemical Biomarkers as Population-Normalization Proxies in Wastewater-Based Epidemiology. |
|---|---|
| Authors: | Laicans, Juris, Bartkevics, Vadims, Pugajeva, Iveta, Dejus, Sandis, Zviedris, Maris, Dejus, Brigita, Juhna, Talis |
| Source: | Water (20734441); Jul2026, Vol. 18 Issue 14, p1766, 25p |
| Subject Terms: | Biomarkers, Public health surveillance, Effluent quality, Epidemiology |
| Geographic Terms: | Latvia |
| Abstract: | Wastewater-based epidemiology (WBE) is increasingly used to monitor public health trends and chemical consumption by analyzing biomarkers in untreated wastewater. As a complementary approach to traditional epidemiological surveillance, WBE provides insights into infectious disease spread, drug use, and pharmaceutical consumption. However, accurate population normalization remains a major challenge, because census-based population estimates often do not correspond to hydrologically defined wastewater catchments. This study evaluates whether routinely monitored wastewater quality parameters can serve as cost-effective population-normalization proxies in WBE. Using data from Latvia's national COVID-19 wastewater surveillance program, the performance of conventional wastewater parameters (BOD |
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| Database: | Biomedical Index |
| FullText | Text: Availability: 0 CustomLinks: – Url: https://resolver.ebsco.com/c/fiv2js/result?sid=EBSCO:edm&genre=article&issn=20734441&ISBN=&volume=18&issue=14&date=20260715&spage=1766&pages=1766-1790&title=Water (20734441)&atitle=Assessing%20the%20Stability%20of%20Routine%20Wastewater%20Parameters%20and%20Chemical%20Biomarkers%20as%20Population-Normalization%20Proxies%20in%20Wastewater-Based%20Epidemiology.&aulast=Laicans%2C%20Juris&id=DOI:10.3390/w18141766 Name: Full Text Finder (for New FTF UI) (ns324271) Category: fullText Text: Full Text Finder MouseOverText: Full Text Finder |
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| Header | DbId: edm DbLabel: Biomedical Index An: 195803975 RelevancyScore: 1061 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 1060.7685546875 |
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| Items | – Name: Title Label: Title Group: Ti Data: Assessing the Stability of Routine Wastewater Parameters and Chemical Biomarkers as Population-Normalization Proxies in Wastewater-Based Epidemiology. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Laicans%2C+Juris%22">Laicans, Juris</searchLink><br /><searchLink fieldCode="AR" term="%22Bartkevics%2C+Vadims%22">Bartkevics, Vadims</searchLink><br /><searchLink fieldCode="AR" term="%22Pugajeva%2C+Iveta%22">Pugajeva, Iveta</searchLink><br /><searchLink fieldCode="AR" term="%22Dejus%2C+Sandis%22">Dejus, Sandis</searchLink><br /><searchLink fieldCode="AR" term="%22Zviedris%2C+Maris%22">Zviedris, Maris</searchLink><br /><searchLink fieldCode="AR" term="%22Dejus%2C+Brigita%22">Dejus, Brigita</searchLink><br /><searchLink fieldCode="AR" term="%22Juhna%2C+Talis%22">Juhna, Talis</searchLink> – Name: TitleSource Label: Source Group: Src Data: Water (20734441); Jul2026, Vol. 18 Issue 14, p1766, 25p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Biomarkers%22">Biomarkers</searchLink><br /><searchLink fieldCode="DE" term="%22Public+health+surveillance%22">Public health surveillance</searchLink><br /><searchLink fieldCode="DE" term="%22Effluent+quality%22">Effluent quality</searchLink><br /><searchLink fieldCode="DE" term="%22Epidemiology%22">Epidemiology</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Latvia%22">Latvia</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Wastewater-based epidemiology (WBE) is increasingly used to monitor public health trends and chemical consumption by analyzing biomarkers in untreated wastewater. As a complementary approach to traditional epidemiological surveillance, WBE provides insights into infectious disease spread, drug use, and pharmaceutical consumption. However, accurate population normalization remains a major challenge, because census-based population estimates often do not correspond to hydrologically defined wastewater catchments. This study evaluates whether routinely monitored wastewater quality parameters can serve as cost-effective population-normalization proxies in WBE. Using data from Latvia's national COVID-19 wastewater surveillance program, the performance of conventional wastewater parameters (BOD<subscript>5</subscript>, COD, suspended solids, total phosphorus, and total nitrogen) was compared with endogenous and exogenous biomarkers, including 5-HIAA, caffeine, cotinine, ethyl sulfate, gabapentin, ibuprofen, and diclofenac. Population estimates based on census and operator data were assessed under varying weather conditions. The results indicate that routine wastewater parameters, particularly total nitrogen, may serve as suitable indicators for population normalization in WBE, with performance comparable to or exceeding that of commonly used biomarkers. These findings support the use of routinely monitored parameters as scalable and accessible tools for improving WBE reliability and strengthening public health surveillance and early warning systems. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Water (20734441) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/w18141766 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 25 StartPage: 1766 Subjects: – SubjectFull: Latvia Type: general – SubjectFull: Biomarkers Type: general – SubjectFull: Public health surveillance Type: general – SubjectFull: Effluent quality Type: general – SubjectFull: Epidemiology Type: general Titles: – TitleFull: Assessing the Stability of Routine Wastewater Parameters and Chemical Biomarkers as Population-Normalization Proxies in Wastewater-Based Epidemiology. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Laicans, Juris – PersonEntity: Name: NameFull: Bartkevics, Vadims – PersonEntity: Name: NameFull: Pugajeva, Iveta – PersonEntity: Name: NameFull: Dejus, Sandis – PersonEntity: Name: NameFull: Zviedris, Maris – PersonEntity: Name: NameFull: Dejus, Brigita – PersonEntity: Name: NameFull: Juhna, Talis IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: Jul2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 20734441 Numbering: – Type: volume Value: 18 – Type: issue Value: 14 Titles: – TitleFull: Water (20734441) Type: main |
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